drug release
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A comparative in vitro drug release prospective with two different polymers for the development of floating single unit dosage form of imatinib mesylate for chronic myelogenous leukemia
... vitro drug release profile of all the formulations could be better expressed by Korsemeyer- Peppas model as they showed a good linearity with ‘R’ value of ...
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Efecto del CIDR (Controlled Internal Drug Release) aplicado después de la inseminación artificial sobre la tasa de preñez en vacas de carne.
... Los objetivos principales de este trabajo fueron aumentar los porcentajes de gestación en bovinos productores de carne en el noreste de México, estableciendo el uso del CIDR (Controlled Internal Drug ...
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Biological Validation of Isorhamnetin Glycosides Loaded Nanofibers as a Drug Release System
... Nanofibers have emerged as a potential novel platform due to its physicochemical properties for healthcare application. Nanofibers advantage rely in their high specific surface area-to- volume ratio and porosity. Their ...
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Enantiomeric separation and determination of stereospecific drug release from marketed racemic omeprazole products by chiral HPLC
... From the S/R ratios of different racemic omeprazole marketed products it was concluded that at 5 and 10 min disso- lution time points there was a stereospecific drug release between the [r] ...
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Formulación y Optimización del Sistema Flotante de Amoxicilina para el tratamiento efectivo de la infección por Helicobacter pylori
... Amoxicillin FRS was successfully developed and optimized by factorial Design with replicates to enhance gastric resi- dence time and drug release to effectively target Helicobacter pylori. It can be ...
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Influence of polymethacrylates and compritol on release profile of a highly water soluble drug metformin hydrochloride
... the drug leading to side effects or toxicities, irregular profile of the plasma drug level, and poor patient ...Controlled release drug delivery systems have the potential of solving these ...
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Encapsulation of olanzapine into beeswax microspheres: preparation, characterization and release kinetics
... The drug release from the bees wax microspheres was found sufficient for oral delivery and the drug release profile was significantly affected by the properties of wax used in the prepar[r] ...
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Preparación y caracterización de 5-FU microesferas cargadas de Eudragit y acetato de celulosa
... The dissolution rate of 5-FU from the microspheres were studied using phosphate buffer solution (PBS) pH 7.4 by paddle method (USP XXIII). Accurately weighed microspheres (equivalent to 10 mg of 5-FU) were taken for ...
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Optimization of Lovastatin Self Nanoemulsifying Solid Dosage Form
... To validate the evolved mathematical models, two check points were selected. Two batches CH1 and CH2 were prepared and evaluated (Table 3). As a confirmation process, a fresh formulation of Lovastatin SNCDF was prepared ...
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Co assembly of tetrapeptides into complex pH responsive molecular hydrogel networks
... Molecular hydrogels – supramolecular hydrogels formed by self- assembly of low-molecular weight compounds – have been widely studied in the last few years because of their potential application in elds as diverse as ...
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Quality by design (QbD) approach to formulate in situ gelling system for nose to brain delivery of Fluoxetine hydrochloride: Ex vivo and In vivo study
... fect of different variables. The optimized formulation F4 containing 0.4% gellan gum and 0.1% HPMC showed high- est drug release (94.24 %) through sheep nasal mucosa. In pharmacodynamic study, the in situ ...
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Formulation and evaluation of baclofen liposome vesicles using lecithin
... cumulative drug release ...cumulative drug release due to the maximum entrapment of drug in the ...(pure drug-about 92 % ...pure drug taken as standard. Therefore, the ...
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Formulation development and Optimization of Diclofenac Sodium Extended release Matrix tablets as per USP standards
... that drug release from optimized formulation (M3) was independent of drug ...the drug released from the formulation by anomalous (non-Fickians) ...
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