Embryonic stem cells (ESC)
Cancer genes hypermethylated in human embryonic stem cells.
... Intriguingly, not all the genes frequently hypermethylated in CCLs were completely unmethylated in all the NTTs analyzed (Figure 1, and Tables 1 and S1). The frequency of hypermethylation in normal tissues is only of ...
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Resveratrol ameliorates the maturation process of β-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells.
... Human embryonic stem cells (hESCs) retain the extraordinary capacity to differentiate into different cell types of an adult organism, including pancreatic β ...differentiating cells assembled ...
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Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival.
... to embryonic stem cell (ESC) biology has not been ...in cells overexpressing ...in cells exposed to LIF deprivation maintained the expression of self-renewal markers, whereas the ...
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Transient Downregulation of Nanog and Oct4 Induced by DETA/NO Exposure in Mouse Embryonic Stem Cells Leads to Mesodermal/Endodermal Lineage Differentiation.
... the pluripotent epigenome keeps the chromatin structure open to allow for rapid genetic regulation [19]. Nitric oxide (NO) is a signalling molecule that plays a role in developmen- tal processes, but the mechanisms ...
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Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder.
... From 106 human blastocyts donate for research after in vitro fertilization (IVF) and preimplantation genetic di- agnosis (PGD) for monogenetic disorder, 3 human embryonic stem cells (hESCs) HVR1, ...
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Rhythmic profile assessment of breast cancer cell lines and adipose derived stem cells after circadian entrainment
... of stem cells is closely related to the cancer and aberrant ...adult stem cells share certain transcriptomic characteristics with Embryonic Stem Cells regulated by master ...
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Las patentes de células madre embrionarias humanas: ¿Amigas o enemigas de las barreras morales?
... later, following the rulings from the Edinburgh case, the enlarged board of appeal of the european Patent office rejected the WARF patent app- lication (ePo board of appeal decision G002/06, 2008), related to an ...
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Las células madre y la medicina regenerativa. De las células madre embrionarias a la reprogramación celular
... so-called stem cells is perhaps an experimental subject of the greatest importance ...Adult stem cells (ASC) are currently used for various ...and embryonic stem cells ...
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Bioethical implications of research on embryonic stem-cells
... Abstract: Embryonic stem-cells are capable of differentiation in diverse cellular types and be used, in the future, for treating degenerative pathologies and ...with embryonic stem ...
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The future of stem cells in liver diseases
... of stem/precursor ...transplanted cells should also be assessed in animal models, with respect to func- tion, possible extra-hepatic localization, genetic/epigenet- ic stability and especially ...hepatic ...
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The concept of pre-embryonic genes
... For example, the bacteriophage lamda repressor does not act at a distance as contrasted with eukaryotic DNA protein promoter factors which interact via distant enhancers. It is believed that this arrangement allows for ...
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TítuloNotch signalling in cancer stem cells
... contain stem cells (called cancer stem cells) and arise from ...for stem cells such as BMP, Notch, Hedgehog and Wnt would allow stem cells to undergo uncontrolled ...
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TítuloWnt signalling and cancer stem cells
... During the process of wound healing in the heart, changes in components of the WNT-Fzd signalling pathway, such as WNT, FZD, DVL1, GSK3B, β-catenin and SFRP can occur. For example, during myoblast proliferation and ...
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Nichos hematopoyéticos en médula osea
... these cells. Are they the same mesenchymal-stem-cell-derived osteoblasts that continue to differentiate into osteocytes, or have they branched off to generate a distinct ‘niche-osteoblast’? ...
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TítuloHedgehog signalling as a target in cancer stem cells
... The structure of the Hh molecule itself is very similar to that of zinc hydrolases and other enzymes, including bacterial ones. This similarly has fuelled speculation that the Hh signalling system is derived from an ...
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Comportamiento de clulas mesenquimales obtenidas de tejidos dentales: Revisin de literatura
... the cells found ...by cells, can increase the proliferation and differentiation of PDLSC ...dental-follicle cells can stimulate the behavior of periodontal- ligament fibroblasts (46), and that ...
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Qu son las clulas troncales o clulas madre?
... of cells has been the most extensive and has been conducted in ...and stem cells antigen ...since cells not showing it presented few cell ...hematopoietic cells repopulation in ...
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Cancer Stem Cells are Depolarized Relative to Normal Stem Cells Derived from Human Livers
... of cells from a primitive to well differentiated phenotype is dependent on a simulta- neous transition from a depolarized to hyperpolarized state, activation of CSCs with GABAergic agents could conceivably result ...
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Adipose derived mesenchymal stem cells : are they a good therapeutic strategy for osteoarthritis? / Elena Damiá, Deborah Chicharro, Sergio López, Belén Cuervo, Mónica Rubio, Joaquín Sopena, José Manuel Vilar and José María Carrillo
... Mesenchymal stem cells (MSCs) are considered to be a promising candidate for cartilage regeneration, due to their ability to differentiate towards cartilage and bone cells and secrete trophic factors ...
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Characterization of Adult Stem/Progenitor Cell Populations From Bone Marrow in a Three-Dimensional Collagen Gel Culture System.
... culture-derived cells, it became very difficult to distinguish the boundaries between the chamber wall and the newly formed tissues, indicating an active remodeling ...ADH cells, we observed that cartilage ...
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