G Protein-coupled Receptor
G protein coupled receptor 30/adenylyl cyclase/protein kinase A pathway is involved in estradiol 17ß D glucuronide induced cholestasis
... dependent protein kinase C, phosphoinositide 3-kinase/protein kinase B, mitogen- activated protein kinases [MAPKs] p38 and extracellular signal-related kinase 1/2, and estrogen receptor alpha) ...
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G Protein Coupled Receptor Family C 6A (GPRC6A): Possible molecular target in Bone
... that this chimera prefers basic L-alpha-amino acids such as arginine, lysine and ornithine, they searched for commercially available analogues of these and other L-alpha-amino acids, and tested them for activity in a ...
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G Protein-coupled receptors as targets for drug design Ania de la Nuez Veulens , Rolando Rodrguez
... Rummel G, Rosen- busch JP, Landau ...in G protein-coupled recep- tors: implications of the high-resolution structure of rhodopsin for structure- function analysis of rhodopsin-like recep- ...
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Analisis de la expresión y la función del receptor sensor de calcio en tumores del desarrollo
... El receptor sensor de calcio (CaR o CaSR, del inglés calcium-sensing receptor) es un receptor acoplado a proteínas G (G-protein coupled receptor, GPCR) que se ...
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The Role of Bile Acids in Glucose Metabolism and Their Relation with Diabetes
... cytoplasmic G protein-coupled receptor TGR5 (TGR5/ M-BAR) and nuclear farnesoid X receptor (FXR) activat- ing different signaling pathways in distinct organs and tis- sues that have ...
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The lipid habitats of neurotransmitter receptors in brain
... the G-protein coupled recep- tors (GPCR) on the ...the receptor with a G protein, triggering a signaling cascade, which takes the form of a metabolic ...
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Cell based high throughput screening assay for identification of G protein coupled receptors agonists and antagonists
... the receptor, Ca 2+ is released into the cytoplasm of the ...no receptor inhibition by the test compound, a normal agonist response will be observed to a known ...
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THE CARBOXY-TERMINAL TAIL OF THE STE2 RECEPTOR IS INVOLVED IN ACTIVATION OF THE G PROTEIN IN THE SACCHAROMYCES CEREVISIAE Α-PHEROMONE RESPONSE PATHWAY
... of G protein-coupled re- ceptors have suggested that not only their intracellular loops but also their carboxy-terminal tails play a crucial role in maintaining a productive G protein ...
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Receptores del hospedero implicados en la invasión del merozoito de Plasmodium falciparum: Revisión
... al receptor de basi- gina (BSG), desencadenando la liberación de las proteínas de las roptrias, proceso mediado por el flujo de Ca 2+ en la interfaz parásito-huésped ...
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Relación de los polimorfismos genéticos OPRM1 y COMT con la eficacia y seguridad del tratamiento con opiáceos en dolor crónico
... En el momento actual,los opioides se han incorporado al tratamiento del dolor crónico no oncológico de intensidad moderada o grave. Sin embargo el uso de opioides no está exento de efectos adversos, especialmente ...
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Estudi dels mecanismes moleculars implicats en l’associació entre inflamació i alteracions metabòliques en cèl∙lules cardíaques
... PGC-1a binds nuclear receptors through the leucine-rich LXXLL motifs designated L2 and L3, which are located within the N terminus of the coactivator. 24 In contrast, NF-kB requires the binding to specific LXXLL motifs ...
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Functional study of potential sHSPs in Arabidopsis and tomato under environmental stress
... each protein sample were loaded on a 10 % SDS polyacrylamide gel and a subject to a current of 30 Milliamperes until samples had migrated 1 cm into the running ...Blue G-250 [Neuhoff, 1988] and distained in ...
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Cycling Dof Factors: Molecular and functional characterization of Arabidopsis thaliana AtCDF3 and tomato (Solanum lycopersicum L.) SlCDF3 in response to abiotic stress
... The family of DOF TFs evolved from a common ancestor in green unicellular algae such as Chlamydomonas reinhardtii, where only one gene has been found, and rapidly expanded in mosses, ferns and vascular plants ...
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Efecto de la sobre-expresión de DNMT3B en la actividad transcripcional de genes relacionados con el cáncer
... Epigenetic and genetic alterations are common in the genesis and progression of various types human cancer. The abnormal expression of genes related to cell cycle, DNA repair, cellular metabolism and tumor suppressor are ...
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Building functional surfaces for biosensors development
... The protein used in this work was lacease, a copper-containing redox enzyme that catalyse the oxidation of a broad range of polyphenols and aromatic substrates, coupled to the reduction[r] ...
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Elastin like polypeptides in drug delivery
... copolymer was incubated with a plasmid containing the Green Fluorescent Protein gene, the resulting polyplexes (Rh ≈ 100 nm) were able to transfect cells and its cytotoxicity was clearly reduced. Therefore, the ...
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Cambios en los niveles de Albúmina Sérica, Proteína C reactiva en sangre y su relación con la Morbimortalidad en varones críticos (caso: pacientes hospitalizados en los Servicios de Medicina Interna del Hospital Arzobispo Loayza 2015)
... UNIVERSIDAD NACIONAL DEL CALLAO ESCUELA DE POSGRADO ?024 SECCION DE POSGRADO FACULTAD DE CIENCIAS EcoN?MIcAs La ' ' ~?f ? 3 ?030? A g \\?030 g ,, // "CAMBlOS EN LOS NIVELES DE ALBUMINA SERICA, PROTEIN[.] ...
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Polarity protein Par3 controls B cell receptor dynamics and antigen extraction at the immune synapse
... fluorescent protein [RFP]) in control and Par3-silenced ...motor protein by TIRFM showed that the duration of single dynein trajectories was significantly reduced in Par3-silenced cells as compared with ...
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Human conditions of insulin like growth factor I (IGF I) deficiency
... Consistently, a large number of studies have previously suggested that the IGF system is involved in mammalian reproductive functions [108,126,127]. First, it has been emphasized the importance of insulin receptor ...
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Lack of association between the protein tyrosine phosphatase non-receptor type 22 R263Q and R620W functional genetic variants and endogenous non-anterior uveitis.
... Riemekasten G, Hunzelmann N, Hesselstrand R, Tan FK, Reveille JD, Assassi S, Garcia-Hernandez FJ, Carreira P, Camps MT, Fernandez-Nebro A, de la Pena PG, Nearney T, Hilda D, Gonzalez-Gay MA, Airo P, Beretta L, ...
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