Gene regulatory networks
TítuloTransient hysteresis and inherent stochasticity in gene regulatory networks
... by gene regulatory motifs with mutually exclusive expression ...to gene expression dynamics is not compatible with hysteresis, since the stationary solution of the governing Chemical Master Equation ...
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Graphlet Based Metrics for the Comparison of Gene Regulatory Networks
... of gene expression remains one of the main challenges in the post-genomic ...in gene expression ...of gene expression is usu- ally depicted in the form of a gene regulatory network ...
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Evolution of form and function in a model of differentiated multicellular organisms with gene regulatory networks
... of gene expression (Levine and Tjian, ...developmental regulatory programs (Davidson, 2006), suggesting that diversity can be better explained by variation in the regulation of gene expres- sion than ...
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Reverse engineering directed gene regulatory networks from transcriptomics and proteomics data of biomining bacterial communities with approximate Bayesian computation and steady state signalling simulations
... undirected networks and used to infer network causality, ...directed networks that can be used for several modelling approaches in order to per- form forward simulations of specific biological functions ...
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Research article Comparative analysis of the transcription-factor gene regulatory networks of E. coli and S. cerevisiae
... despite the strong similarities observed in the bipartite- network link distributions (see Figure 3). Furthermore, the connectivity distributions of the original and rand- omized RG-projected networks are very ...
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Análisis funcional de genes cruciales para el desarrollo de sitios de alimentación inducidos por nematodos agalladores (Meloidogyne spp.) en arabidopsis
... the regulatory module miR172-AP2 also plays a role during the formation of nodules in legumes (Yan et ...common regulatory networks mediated by miR172 in apparently distant processes of development ...
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The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis
... Systemic sclerosis (SSc) is a chronic multisystem connective tissue disorder characterized by fibrotic events, vascular damage and autoantibody production. Two main clinical subtypes have been defined based on the extent ...
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Genomics and Systems Biology Approaches in the Study of Lipid Disorders
... identify gene coexpression modules summarizing the main trends in a variation on the transcriptome data and subsequently the coexpression modules can be linked to clinical traits or binary outcomes and DNA/ RNA ...
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Synthetic Biology: Opportunities for Chilean Bioindustry and education
... molecular networks (Pedraza and van Oudenaarden, 2005; Elowitz et ...of gene regulation (Damle and Davidson 2012; Becskei and Serrano, 2000; Cantone et ...
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TítuloThe 5S rDNA gene family in mollusks: characterization of transcriptional regulatory regions, prediction of secondary structures, and long term evolution, with special attention to Mytilidae mussels
... According to the 3 phylogenies obtained (α, β, and δ, Figures 1–3), many sequences showed a between- species gene clustering pattern (e.g., α type topology, Figure 1). In fact, an M. edulis (PE) clone clustered ...
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Up-regulation of placental leptin by human chorionic gonadotropin.
... leptin gene was identified that works in choriocarcinoma lines but not adipose cells ...leptin gene is actively engaged by hypoxia through mechanisms that are common to other hypoxia-inducible genes ...
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Reconstruction problems for LGT networks
... LGT networks for an arbitrary choice of F ...restricted networks have isomorphic reduced principal subtrees, then the nodes and arcs of both trees can be ...different networks are “the same”, ...
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Blending networks networks in translation
... Non-set relation between linguistic form and conceptual structure makes language more flexible in meaning construction in basically four ways (Gille Fauconnier and Mark Turner 2002:119-135): simplex networks, ...
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Aprendizaje profundo aplicado a problemas de predicción de supervivencia en cáncer
... each gene-expression-profile conforms a treemap image in which the expression of those genes belonging to the same chromosome are placed in the same area of the ...equip gene-expression-profiles with ...
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VirtualPlant: A Software Platform to Support Systems Biology Research
... or gene products that cannot be associated to another gene in the genome by any known or predicted molecular interaction are not included in the ...predicted regulatory network contains 21,698,658 ...
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Modelling transcriptional regulation using switched dynamical latent force models
... As we described in section 7.2, E.coli is a robust organism that can adapt remarkably well to changes in its environment [23]. The sudden oxygen starvation in the environment provokes the necessity of routinely ...
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Estudio de la variabilidad de la tolerancia a bajas temperaturas en trigo candeal (Triticum turgidum ssp. durum) y genes asociados
... Cultivated germplasm in our country is reduced to a few varieties with spring habit, with scarce description about determinants of flowering date and performance under low temperatures. The complex inheritance of this ...
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BZIP transcription factors and transcriptional regulatory networks in the neurospora circadian system
... different inputs that each gene has, under different conditions, which could override (or mask) their control by the clock. When integrating data then, from different studies using various experimental settings, ...
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Apolipoprotein D alters the early transcriptional response to oxidative stress in the adult cerebellum
... RNAs for qRT-PCR experiments were extracted with TRIzol (Invitrogen) either from the pooled samples of mouse cerebella described above, from homogenized mouse diencephalons, or from cultured astroglial cells. Total RNA ...
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TítuloInterplay between cardiac transcription factors and non coding RNAs in predisposing to atrial fibrillation
... putative gene regulatory networks including cardio-enriched transcription factors, such as PITX2, TBX5, ZFHX3, and SHOX2, and their effector/target genes along with downstream non-coding RNAs can ...
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