growth hormone
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TítuloTreatment with growth hormone for adults with growth hormone deficiency syndrome: benefits and risks
... of growth hormone deficiency (GHD) in adults began in clinical practice more than 20 years ...this hormone in patients who have completed longitudinal ...GH hormone receptor polymorphism could ...
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Ten years' clinical experience with biosimilar human growth hormone: a review of efficacy data
... A summary of the clinical studies in the Omnitrope devel- opment program is provided in Table 1. The objectives of the Phase III clinical development program for biosimilar rhGH were to demonstrate its therapeutic ...
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TítuloGhrelin and growth hormone secretagogues, physiological and pharmacological aspect
... “growth hormone secretagogues” (GHSs) were discovered by Bowers et ...stimulate growth hormone (GH) release, via a separate pathway distinct from GH releasing hormone ...
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Growth Hormone Releasing Peptide 6 (GHRP6) reduces liver fibrosis in CCl4 chronically intoxicated rats
... ABSTRACT Tissue fibrosis is a leading cause of morbidity and mortality. Current treatments for conditions such as hepatic fibrosis have been unsuccessful. The growth hormone relasing peptide 6 (GHRP6) is ...
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TítuloSexual dimorphism on growth hormone secretion after oral glucose administration
... seems to disrupt the feedback loop of ghrelin and GH, leading to elevated ghrelin levels, but does not modify leptin levels [41]. In addition, treatment with recombinant growth hormone in patients with ...
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TítuloInfluence of ghrelin and growth hormone deficiency on AMP activated protein kinase and hypothalamic lipid metabolism
... peptide hormone from the ...the growth hormone (GH) secretagogue receptor (GHS-R) (13), which in the hypothalamus, is expressed in NPY/AGRP-, POMC-, and growth hormone releasing ...
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TítuloEffect of oral glucose administration on rebound growth hormone release in normal and obese women: the role of adiposity, insulin sensitivity and ghrelin
... decreased growth hormone (GH) secretion ...releasing hormone (GHRH) plus GH-Releasing Peptide-6, which resulted in a massive GH re- sponse for obese subjects ...
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Insulin like growth factor I restores the reduced somatostatinergic tone controlling growth hormone secretion in cirrhotic rats
... 1. Growth hormone (GH) response to pyridostigmine or sa- line bolus in the three experimental ...lin-like growth factor-I (IGF-I) (CIπIGFπPD, nΩ6) as com- pared to the control group (CO, nΩ6) and the ...
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Melatonin and growth hormone deficiency: a contribution to the evaluation of neuroendocrine disorders
... Melatonin, a hormone secreted by the pineal gland, constitutes a landmark in neuroendocrine integration. The relationship between melatonin and different pituitary hormones and sex steroids has been studied; ...
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Human Growth Hormone (GH) Receptor and the High Affinity GH Binding Protein
... circulating growth hormone (GH) is partly bound to a high-affinity binding protein (GHBP) which is derived from proteolytical cleavage of the extracellular domain of the GH ...
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TítuloOral glucose stimulated growth hormone (GH) test in adult GH deficiency patients and controls: potential utility of a novel test
... with growth hormone (GH) deficiency (GHD) have increased fat mass and reduced muscle mass, low energy, and reduced quality of ...pituitary hormone deficiencies are at risk for ...as growth ...
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Assessment of growth hormone secretagogues in anti-doping
... all growth hormone secretagogues and the competition against the labeled ligand for the receptor, this screening test is applicable for current GHS but already anticipates future pharmaceutical developments ...
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Metabolic Abnormalities in growth hormone deficiency
... cents we were unable to find any abnormalities in cardiac mass, as the interventricular septal thic- kness, the left ventricular posterior wall thickness and the left ventricular mass after correction for body surface ...
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TítuloThe decreased growth hormone response to growth hormone releasing hormone in obesity is associated to cardiometabolic risk factors
... Hindawi Publishing Corporation Mediators of Inflammation Volume 2010, Article ID 434562, 8 pages doi 10 1155/2010/434562 Research Article The Decreased Growth Hormone Response to Growth Hormone Releas[.] ...
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Improvement in growth after two years of growth hormone therapy in very young children born small for gestational age and without spontaneous catch-up growth: results of a multicenter, controlled, randomized, open clinical trial.
... catch-up growth (as defined below) at the time of inclusion and who were recruited from 14 participating ...catch-up growth [height ⬍ 3rd centile for CA according to the growth curves of Herna´ndez ...
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TítuloGastrointestinal Spatiotemporal mRNA Expression of Ghrelin vs Growth Hormone Receptor and New Growth Yield Machine Learning Model Based on Perturbation Theory
... the growth yield using new Ghrelin and Growth mRNA expressions measured under the model experimental conditions: one of the eight segments of the GIT, one of the seven sampling time points and one of the ...
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A novel controlled drug delivery system for growth hormone applied to healing skin wounds in diabetic rats
... Although wound repair is a complex process involving several cell types [2, 3], the degree and quality of repair can been modulated using different types of growth factors. The ef ciency of controlled release ...
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TítuloCentral ghrelin regulates peripheral lipid metabolism in a growth hormone independent fashion
... peptide hormone from the stomach and acts as the endogenous ligand to GH secretagogue receptor (GHS-R) (8–11), which is expressed in the brain and peripheral tissues ...
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E180splice Mutation in the Growth Hormone Receptor Gene in a Chilean Family with Growth Hormone Insensitivity: A Probable Common Mediterranean Ancestor
... The determination of the intron 9 haplotype revealed a co-segregation of the E180splice mutation with haplotype I in the Chilean family, as described for the Ecuadorian cohort, and the I[r] ...
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TítuloGrowth hormone, ghrelin and peptide YY secretion after oral glucose administration in healthy and obese women
... The mechanism of the altered GH secretion in obesity is unclear. There is evidence that oral glucose (OG) administration initially decreases and subsequently stimulates GH secretion. Ghrelin is a peptide that displays ...
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