... modified antibodies and data analysis. JF: Production of TA3-MTXR murine mammary tumor cell line and data discussion. AF: Analysis, interpretation of data, manuscript writing, drafting, revision for intellectual content ...
... CB[7]NPs were used to adsorb, deliver and release the anti- cancer therapeutic doxorubicin. Intracellular delivery, with gradual (low pH, GSH) or fast and on-demand (heat) release of Dox, was demonstrated in HeLa cells ...
... The appearance of free radicals induced by ASW can cause the changes described above. However, we suppose that the nonlinear nature of these effects can be due not only to the free radicals generated by ASW, but also the ...
... the growthinhibition at higher acetate or malonate concentrations, it is important to note the strong effect on the stimulation of astaxanthin synthesis and accumulation being astaxanthin concentration ...
... methanol solutions, the solvent was removed under reduced pressure to yield 124.0 g of combined extract. This extract was analyzed for anti-amoebic activity, showing a 90.5% growthinhibition on ...
... vitro growthinhibition of sev- eral tumor cell lines, whereas it induced proliferation and activation of peripheral blood lymphocytes ...this inhibition were identified as cell cycle arrest and ...
... overlapping growth curves of Figure ...colony, growth of the cells of the facing edge stops completely and the colony grows, extending its area in the non-facing ...that growthinhibition ...
... population growth rate and the immigrant population/total population ratio will also be consid- ered as stochastic variables, given the uncertain elements affecting fertility and mortality rates and ...lation ...
... the inhibition of UGT1A1 by levothyroxine which is clinically used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid ...the inhibition of UGT1A1 by levothyroxine was ...
... The growth of rat hepatoma 7288CTC in vivo is stimulated by the uptake of linoleic acid (LA) and its metabolism to 13-hydroxyoctadecadi- enoic acid (13-HODE), an important mitogenic signaling molecule within this ...
... Transforming growth factor b1 (TGF-b1) is a pleiotropic cytokine, which displays potent profibrogenic effects and is highly expressed in fibrotic ...TGF-b1-dependent inhibition of MV1Lu proliferation in vitro ...
... that inhibition of Gal-1 expression using siGal-1 RNA markedly decreases tPA induced ERK1/2 activation and proliferation, confirming the crucial role of Gal-1 in tPA induced mitogenic process in pancreatic cancer ...
... Business growth and its determining factors are relevant for multiple reasons; for example, high-growth businesses promote a country’s economic growth because more high-growth businesses ...
... the growth period is mainly accounted for by an increase in capital accumulation and knowledge transfer associated with foreign investment in the booming oil industry whereas the collapse period is accounted for ...
... In this study, we were interested in establishing the importance of the TCA cycle enzyme succinate dehydrogenase, which catalyzes the conversion of succinate to fumarate, in the func- tioning of the illuminated leaf. ...
... development. Inhibition of mTOR with rapalogs has shown clinical efficacy against some solid tumors, including everolimus for angiomyolipoma associated with tuberous sclerosis, metastatic renal cell carcinoma, ...
... transforming growth factor (TGF)-b1 has been shown to restore damaged skin and increase epidermal thickening and the Grenz zone layer; histologic studies have shown in- creased epidermal thickness and fibroblast ...
... Fibrosis is a pathological condition characterized by the replacement of normal and functional tissue by connec- tive tissue with excessive accumulation of extracellular matrix (ECM) proteins (Graham et al. 2010; Leask ...