... in human adipocytes revealed GIP as an insulin-sensitizer ...in human fat cells cultured in ...in humanadipose-derived stem cells from lean ...in human fat cells obtained from an obese ...
... Our study design also allowed us to investigate the relationship between FASN mRNA expression and serum concentrations of adipocytokines (leptin and adi- ponectin). We found a correlation between FASN and serum ...
... Interestingly, we found that ASCs from obese mouse and humanadiposetissue contained a greater quantity of mitochondria and produce more ROS (Fig 2). It is acknowledged that mito- chondrial function ...
... in human preadipocytes and adipocytes and in 3T3-L1 ...of adiposetissue to circulating irisin concentration, we found a significant as- sociation between AT FNDC5 mRNA and circulating iri- sin ...of ...
... Da Silva Meirelles, L., Malta, T. M., De Deus Wagatsuma, V. M., Palma, P. V., Aráujo, A. G., Ribeiro, Malmegrim, K. C., Morato de Oliveira, F., Panepucci, R. A., Silva, W. A. Jr., Kashima Haddad, S. y Covas, D. T. ...
... In conclusion, our data demonstrate for the first time that the level of Munc18c gene expression in humanadiposetissue is down-regulated in morbid obesity. We found that Munc18c gene expression was ...
... Despite using similar pathways and mediators, the inflammatory response in obesity differs substantially in duration and intensity from that observed in the more familiar setting of infection. For instance, infectious ...
... The localization of circulating leukocytes within inflamed tissues occurs as the result of interactions with and migration across vascular endothelium, and is governed, in part, by the expression of adhesion molecules on ...
... Fat tissue was homogenized in radioimmunoprecipitation assay buffer as we described previously (10). Protein extracts (10 g) were loaded, resolved on 10% SDS-PAGE, and trans- ferred to Hybond ECL nitrocellulose ...
... esperar que las CMM estimulen la proliferación de los linfocitos T, por lo tanto, sean rechazadas por el receptor en caso de células alogénicas o xenogénicas. Sin embargo, diversos experimentos demuestran que no estimula ...
... non-tumoral tissue (Makale et ...tumoral tissue has promoted the development of strategies to minimize radiotherapy side ...Similarly, human embryonic stem cell-derived oligodendrocyte progenitors ...
... For protein detection in Western blot, fat tissue and cellular debris were homogenized in radioimmnuno precipitation assay (RIPA) buffer (0.1% SDS, 0.5% sodium deoxycholate, 1% Nonidet P-40, 150 mM NaCl, 50 mM ...
... either adiposetissue or Validation results are summarised in Table ...of tissue. ranges. In adiposetissue a small bias in sample A 50-ml volume of the vitamin K working solution 1 ...
... White adiposetissue (WAT) mainly stores large amount of lipids as a buffer for energy supply during fasting and secrete a vast number of protein products with hormone function ...brown adipose ...
... against human EGF (Z-‐12) (sc-‐275) (Santa Cruz Biotechnology, Dallas, TX, USA) and a secondary antibody coupled to horseradish peroxidase (Dako, Glostrup, ...
... 52. Bruun JM, Helge JW, Richelsen B, Stallknecht B. Diet and exercise reduce low-grade inflammation and macrophage infiltration in adiposetissue but not in skeletal muscle in severely obese subjects. Am J ...
... In this study, we have used gene expression and western blot analyses to investigate the mitochondrial FAO cap- acity of maternal and fetal blood. We took advantage of comparing different tissues from the same pregnant ...
... The relationship between obesity and cardiovas- cular disease is complex due to the several patho- physiological mechanisms involved and the large number of interrelated factors 4 . Obesity can cause high blood pressure, ...
... MSCs are being used to facilitate the engraftment of trans- planted HSCs and to treat graft-versus-host disease (GVHD) after allogeneic haematopoietic stem cell transplantation (HSCT) based on their immunomodulatory ...