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Human embryonic stem cells

Resveratrol ameliorates the maturation process of β-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells.

Resveratrol ameliorates the maturation process of β-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells.

... Human embryonic stem cells (hESCs) retain the extraordinary capacity to differentiate into different cell types of an adult organism, including pancreatic β ...differentiating cells ...

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Cancer genes hypermethylated in human embryonic stem cells.

Cancer genes hypermethylated in human embryonic stem cells.

... Intriguingly, not all the genes frequently hypermethylated in CCLs were completely unmethylated in all the NTTs analyzed (Figure 1, and Tables 1 and S1). The frequency of hypermethylation in normal tissues is only of ...

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TítuloHuman amniotic membrane as an alternative source of stem cells for regenerative medicine

TítuloHuman amniotic membrane as an alternative source of stem cells for regenerative medicine

... allogenic stem cells has been suggested as an alternative therapeutic approach for treatment of cartilage defects (Jung et ...using human embryonic stem cells ...in ...

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Las patentes de células madre embrionarias humanas: ¿Amigas o enemigas de las barreras morales?

Las patentes de células madre embrionarias humanas: ¿Amigas o enemigas de las barreras morales?

... later, following the rulings from the Edinburgh case, the enlarged board of appeal of the european Patent office rejected the WARF patent app- lication (ePo board of appeal decision G002/06, 2008), related to an ...

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Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder.

Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder.

... 106 human blastocyts donate for research after in vitro fertilization (IVF) and preimplantation genetic di- agnosis (PGD) for monogenetic disorder, 3 human embryonic stem cells (hESCs) ...

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The impact of transposable element activity on therapeutically relevant human stem cells

The impact of transposable element activity on therapeutically relevant human stem cells

... early embryonic period is replication-coupled dilution of 5mC [199, 200], an active mechanism dependent on TET enzymes has recently been uncovered to erase DNA methylation at specific loci in this period [170, ...

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Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy

Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy

... context, stem cell-based therapy represents a novel alternative to attenuate radiation-induced brain injury (Acharya et ...neural stem cells (NSCs), which were injected via tail vein 24 h after ...

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TítuloProteomic applications in the study of human mesenchymal stem cells

TítuloProteomic applications in the study of human mesenchymal stem cells

... Mesenchymal stem cells (MSCs) are undifferentiated cells with an unlimited capacity for self-renewal and able to differentiate towards specific lineages under appropriate ...to embryonic ...

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Biotechnological approaches to cardiac differentiation of human induced pluripotent stem cells

Biotechnological approaches to cardiac differentiation of human induced pluripotent stem cells

... cardiac stem cells (Messina et ...and cells weren’t able to electrically integrate, arising chances of arrhythmias (Menasche et ...of embryonic stem cells, which are derived from ...

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FGF2 plays a key role in embryonic cerebrospinal fluid trophic properties over chick embryo neuroepithelial stem cells

FGF2 plays a key role in embryonic cerebrospinal fluid trophic properties over chick embryo neuroepithelial stem cells

... For the different sets of experiments, cultures were made only in a serum- free medium (400 μ l per dish) as negative controls, or alternatively they were supplemented with the following: (1) E-CSF from H.H. 25 chick ...

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Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival.

Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival.

... to embryonic stem cell (ESC) biology has not been ...in cells overexpressing ...in cells exposed to LIF deprivation maintained the expression of self-renewal markers, whereas the ...

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Proposals for embryonic stem cell production without destroying human embryos: scientific and bioethical challenges

Proposals for embryonic stem cell production without destroying human embryos: scientific and bioethical challenges

... ripotent stem cells (iPSC). These cells demonstrated some of the typical characteristics of ESC: pluripotency markers, capacity to form teratomas and to produce fetal chimeras when injected in a ...

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Bioethical implications of research on embryonic stem-cells

Bioethical implications of research on embryonic stem-cells

... Abstract: Embryonic stem-cells are capable of differentiation in diverse cellular types and be used, in the future, for treating degenerative pathologies and ...with embryonic stem ...

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Generation of human dopaminergic neurons from induced pluripotent stem cells to model Parkinson's disease

Generation of human dopaminergic neurons from induced pluripotent stem cells to model Parkinson's disease

... mouse embryonic stem cells (mESC) overexpressing Lmx1a, where the authors showed higher levels of mDA neurons in overexpressing cells (Friling et ...

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Protocols to differentiate embryonic stem cells into insulin-producing cells

Protocols to differentiate embryonic stem cells into insulin-producing cells

... Embryonic stem cells represent an interesting alternative to treat dia- betes due to their two main properties: self-renewal by symmetric divisions, and the potential for cell differentiation into ...

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Cancer Stem Cells are Depolarized Relative to Normal Stem Cells Derived from Human Livers

Cancer Stem Cells are Depolarized Relative to Normal Stem Cells Derived from Human Livers

... The results of the present study indicate that primary CSCs derived from human HCC are significantly depo- larized relative to NSCs derived from the same livers. They also indicate that the differences in membrane ...

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Terapia celular dirigida contra la sordera: estudio de la capacidad de transdiferenciación de células madre mesenquimales humanas y de fibroblastos hacia células sensoriales del oído interno

Terapia celular dirigida contra la sordera: estudio de la capacidad de transdiferenciación de células madre mesenquimales humanas y de fibroblastos hacia células sensoriales del oído interno

... of stem cells in the post-natal inner ear appears contradictory with the observed lack of regeneration in the mature cochlea following otic ...sphere-forming cells in early postnatal cochleae ...

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Células madre mesenquimales para la regeneración de tejidos: ¿Por qué siguen siendo una promesa sin cumplir?

Células madre mesenquimales para la regeneración de tejidos: ¿Por qué siguen siendo una promesa sin cumplir?

... mesenchymal stem cells (MSCs) were recognized as an important therapeutic alternative for diseases characterized by acute or chronic loss of tissue, thanks to their proliferation and differentiation ...

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TítuloProstate carcinoma and stem cells

TítuloProstate carcinoma and stem cells

... Stem cells, as classically defined, are cells with a capacity to self-renew and to generate daughter cells that can differentiate down several cell lineages to form all of the cell types that ...

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Material agency in the laboratory and the clinic

Material agency in the laboratory and the clinic

... 6 shape the experiences of clinicians and researchers who come into contact with them. In countering the universalizing tendencies of the ELSI literatures to view embryos, researchers and clinicians as abstract entities ...

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