... Humanembryonicstemcells (hESCs) retain the extraordinary capacity to differentiate into different cell types of an adult organism, including pancreatic β ...differentiating cells ...
... Intriguingly, not all the genes frequently hypermethylated in CCLs were completely unmethylated in all the NTTs analyzed (Figure 1, and Tables 1 and S1). The frequency of hypermethylation in normal tissues is only of ...
... allogenic stemcells has been suggested as an alternative therapeutic approach for treatment of cartilage defects (Jung et ...using humanembryonicstemcells ...in ...
... later, following the rulings from the Edinburgh case, the enlarged board of appeal of the european Patent office rejected the WARF patent app- lication (ePo board of appeal decision G002/06, 2008), related to an ...
... 106 human blastocyts donate for research after in vitro fertilization (IVF) and preimplantation genetic di- agnosis (PGD) for monogenetic disorder, 3 humanembryonicstemcells (hESCs) ...
... early embryonic period is replication-coupled dilution of 5mC [199, 200], an active mechanism dependent on TET enzymes has recently been uncovered to erase DNA methylation at specific loci in this period [170, ...
... context, stem cell-based therapy represents a novel alternative to attenuate radiation-induced brain injury (Acharya et ...neural stemcells (NSCs), which were injected via tail vein 24 h after ...
... Mesenchymal stemcells (MSCs) are undifferentiated cells with an unlimited capacity for self-renewal and able to differentiate towards specific lineages under appropriate ...to embryonic ...
... cardiac stemcells (Messina et ...and cells weren’t able to electrically integrate, arising chances of arrhythmias (Menasche et ...of embryonicstemcells, which are derived from ...
... For the different sets of experiments, cultures were made only in a serum- free medium (400 μ l per dish) as negative controls, or alternatively they were supplemented with the following: (1) E-CSF from H.H. 25 chick ...
... to embryonicstem cell (ESC) biology has not been ...in cells overexpressing ...in cells exposed to LIF deprivation maintained the expression of self-renewal markers, whereas the ...
... ripotent stemcells (iPSC). These cells demonstrated some of the typical characteristics of ESC: pluripotency markers, capacity to form teratomas and to produce fetal chimeras when injected in a ...
... Abstract: Embryonicstem-cells are capable of differentiation in diverse cellular types and be used, in the future, for treating degenerative pathologies and ...with embryonicstem ...
... mouse embryonicstemcells (mESC) overexpressing Lmx1a, where the authors showed higher levels of mDA neurons in overexpressing cells (Friling et ...
... Embryonicstemcells represent an interesting alternative to treat dia- betes due to their two main properties: self-renewal by symmetric divisions, and the potential for cell differentiation into ...
... The results of the present study indicate that primary CSCs derived from human HCC are significantly depo- larized relative to NSCs derived from the same livers. They also indicate that the differences in membrane ...
... of stemcells in the post-natal inner ear appears contradictory with the observed lack of regeneration in the mature cochlea following otic ...sphere-forming cells in early postnatal cochleae ...
... mesenchymal stemcells (MSCs) were recognized as an important therapeutic alternative for diseases characterized by acute or chronic loss of tissue, thanks to their proliferation and differentiation ...
... Stemcells, as classically defined, are cells with a capacity to self-renew and to generate daughter cells that can differentiate down several cell lineages to form all of the cell types that ...
... 6 shape the experiences of clinicians and researchers who come into contact with them. In countering the universalizing tendencies of the ELSI literatures to view embryos, researchers and clinicians as abstract entities ...