in vitro drug release
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A comparative in vitro drug release prospective with two different polymers for the development of floating single unit dosage form of imatinib mesylate for chronic myelogenous leukemia
... K15M in various proportions. FTIR spectrogram of pure drug Imatinib and two formulations of both grades of HPMC were comparable with respect to the peek intensity, revealed there is no interaction of the ...
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Estudio de estabilidad realizado en tabletas de Raloxifeno
... Results: in the accelerated stability study, the percentages of dissolved drug were more than 90 % and drug content porcentages were between 90 % and 110 ...months in the studied containers ...
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Development and characterization of controlled release mucoadhesive tablets of captopril
... K15M in various ...and in-vitro drug ...slow release up to 11-12 ...and in vitro drug release was found to be ...change in bioadhesive strength and ...
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Hydrophilic polymers as release modifiers for primaquine phosphate: effect of polymeric dispersion
... the release through diffusion and erosion process by forming a gelatinous swollen mass, the rate of swelling and erosion is related and may also affect the mechanism and kinetics of drug ...medium in ...
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Design and in vitro evaluation of chlorpheniramine maleate from different eudragit based matrix patches: Effect of platicizer and chemical enhancers
... shown in experiments involving two different moist atmospheres namely in 75% and 93% ...patch in higher percentage during the moisture content and water absorption ...contents in the matrix ...
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Miconazole microsponges based topical delivery system for diaper dermatitis
... Microsponges were prepared by quasi emulsion solvent diffusion as shown in Table 2. The required amount of miconazole nitrate and Eudragit RS100 polymer were weighed accurately and dissolved in 5ml of ...
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Development and Evaluation of Isoniazid Loaded Silk Fibroin Microsphere
... soaring drug dose has essential to be managed since merely little slice of the entire dose reaches the ...out in: (i) Express drug deliv- ery to the unhealthy person; (ii) The targeting of alveolar ...
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Quality by design (QbD) approach to formulate in situ gelling system for nose to brain delivery of Fluoxetine hydrochloride: Ex vivo and In vivo study
... strength, drug content, ex-vivo drug permeation, in vivo pharmacodynamic and stability ...increase in viscosity and mucoadhesive strength and decrease in percent ...highest drug ...
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Desarrollo de un novedoso protocolo para el monitoreo preclnico de sistemas de liberacin mucosal con capacidad adyuvante
... of in-vitro monitoring model in vaccine downstream preparation: In vaccine research generally and specifically the mucosal vaccine development, up-to-date there is a gap in checking the ...
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Design and evaluation of cedrela gum based microparticles of theophilline
... and drug. These studies are valuable in the investigation of the crystallinity of drugs in polymeric ...and drug-loaded microparticles at the same range, indicating amorphous nature of ...
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Dissolution behaviour of aceclofenac PVP coprecipitates
... the drug in melted carrier. Amorphous nature of the drug in coprecipitates was confirmed by scanning electron microscopy and a decrease in enthalpy of drug melting in ...
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