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Insulin-like Growth Factor-I (IGF-I)

Human conditions of insulin like growth factor I (IGF I) deficiency

Human conditions of insulin like growth factor I (IGF I) deficiency

... and insulin, IGF-I is a nat- ural peptide already produced in humans, what facilitates the elucidation of possible secondary effects due to rhIGF-I ...the insulin like action of ...

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Hepatoprotective effects of insulin like growth factor I in rats with carbon tetrachloride induced cirrhosis

Hepatoprotective effects of insulin like growth factor I in rats with carbon tetrachloride induced cirrhosis

... / IGF animals these parameters did not differ from healthy ...rats, IGF-I treatment significantly increased clotting factor activity and nor- malized prothrombin ...for IGF-I, 8 ...

10

Enhanced actions of insulin like growth factor I and interferon  alfa co administration in experimental cirrhosis

Enhanced actions of insulin like growth factor I and interferon alfa co administration in experimental cirrhosis

... of IGF-I on the cirrhotic liver (10–13). Low doses of IGF-I induced a hepatoprotective effect with several antioxidant and anti-inflammatory actions, redu- cing hepatic lipid peroxidation, ...

10

Low doses of insulin like growth factor I improve insulin resistance, lipid metabolism and oxidative damage in aging rats

Low doses of insulin like growth factor I improve insulin resistance, lipid metabolism and oxidative damage in aging rats

... of IGF-I may be caused by decreased peroxidative cell ...by IGF-I against free radical damage, we investigated the effect of IGF-I on anti- oxidant enzymes and mitochondrial ...

10

Antifibrogenic effect in vivo of low doses of insulin like growth factor I in cirrhotic rats / Inma Castilla Cortázar     [et al ]

Antifibrogenic effect in vivo of low doses of insulin like growth factor I in cirrhotic rats / Inma Castilla Cortázar [et al ]

... Liver hydroxyproline levels were determined as a rough index of collagen content by multiplying the hydroxyproline content by the factor 7.46 [28]. Brie£y, 50 mg aliquots of liver tissue were hydrolyzed for 22 h ...

11

Low doses of insulin like growth factor I induce mitochondrial protection in aging rats

Low doses of insulin like growth factor I induce mitochondrial protection in aging rats

... Serum IGF-I levels decline with ...of IGF-I restores IGF-I circulating levels and age related- changes, improving glucose and lipid metabolisms, increasing testosterone levels ...

8

Impaired intestinal sugar transport in cirrhotic rats correction by low doses of insulin like growth factor I

Impaired intestinal sugar transport in cirrhotic rats correction by low doses of insulin like growth factor I

... as healthy controls; one of them (CO group) received saline, formed at 0 – 4 7 C. The everted jejunum was placed in 2 mmol/ and the other was treated with IGF-I (CO / IGF ) at the same L Tris-HCl (pH ...

8

Effect of insulin like growth factor I on in vivo intestinal absorption of D galactose in cirrhotic rats

Effect of insulin like growth factor I on in vivo intestinal absorption of D galactose in cirrhotic rats

... Although IGF-I is synthesized in many tissues, it is mainly produced in the liver on stimulation by growth hormone ...(11). IGF-I receptors are densely expressed in the intestinal tract ...

6

Altered intestinal transport of amino acids in cirrhotic rats : the effect of insulin like growth factor I

Altered intestinal transport of amino acids in cirrhotic rats : the effect of insulin like growth factor I

... of IGF-I (7, 12, 17, 37), a hormone that exerts important trophic activities on the intestine (25, 39, ...42). IGF-I receptors are densely expressed in the intestinal tract (24, 27, 33, 35, ...

6

Altered liver gene expression in CC14 cirrhotic rats is partially normalized by insulin like growth factor I

Altered liver gene expression in CC14 cirrhotic rats is partially normalized by insulin like growth factor I

... [40]. IGF-I administration partially counteracted the induction of this gene, suggesting that this growth factor is capable of modulating the hepatic inflammatory response elicited in this ...

11

Insulin like growth factor I restores the reduced somatostatinergic tone controlling growth hormone secretion in cirrhotic rats

Insulin like growth factor I restores the reduced somatostatinergic tone controlling growth hormone secretion in cirrhotic rats

... 1. Growth hormone (GH) response to pyridostigmine or sa- line bolus in the three experimental ...lin-like growth factor-I (IGF-I) (CIπIGFπPD, nΩ6) as com- pared to the ...

5

Little effects of Insulin like Growth Factor I on testicular atrophy induced by hipoxia

Little effects of Insulin like Growth Factor I on testicular atrophy induced by hipoxia

... 0.001). IGF-I therapy induced a significant improvement of this parameter ...receiving IGF-I (see Figure 2 for morphological compari- son among ...

10

Antioxidant effects of insulin like growth factor I (IGF I) in rats with advanced liver cirrosis

Antioxidant effects of insulin like growth factor I (IGF I) in rats with advanced liver cirrosis

... Normally the average of transferrin iron saturation is about one third of the full capacity, thereby ensuring that there is virtually no free iron circulating in the extracellu- lar fluids. At pH 7.4, the ...

8

Mitochondrial protection by low doses of insulin like growth factor I (IGF I) in experimental cirrosis

Mitochondrial protection by low doses of insulin like growth factor I (IGF I) in experimental cirrosis

... of IGF- Ⅰ treatment, groups CI and CI + IGF- Ⅰ showed similar serum levels of alanine aminotransferase, aspartate aminotransferase, glucose, cholesterol, alkaline phosphatase, bilirrubin, total protein and ...

9

Insulin like growth factor I reverts testicular atrophy in rats with advanced cirrhosis

Insulin like growth factor I reverts testicular atrophy in rats with advanced cirrhosis

... Statistical Analysis. Data are expressed as mean 6 SEM. To assess the homogeneity among the 3 groups of rats, a Kruskal-Wallis test was used, followed by multiple post-hoc comparisons using the Mann-Whitney U test ...

9

Insulin like growth factor I (IGF I) replacement therapy increases albumin concentration in liver cirrhosis : results of a pilot randomized controlled clinical trial

Insulin like growth factor I (IGF I) replacement therapy increases albumin concentration in liver cirrhosis : results of a pilot randomized controlled clinical trial

... total IGF- I, free IGF-I and IGFBP-3 are decreased while GH is increased, indicating resistance to GH and reduced hepatic functional reserve ...an IGF- I deficiency state, the ...

7

Characterization of the ANGPT1/TIE2 axis in cancer cell  dormancy  Caracterización del eje ANGPT1 / TIE2 en la dormancia de las células cancerosas

Characterization of the ANGPT1/TIE2 axis in cancer cell dormancy Caracterización del eje ANGPT1 / TIE2 en la dormancia de las células cancerosas

... further growth depends on the ability of the tumor to gain access to the circulatory system, via ...cells like macrophages and lymphocytes which serve as growth promoters in this ...

120

Trastornos de la conducta alimentaria como factor de riesgo para osteoporosis

Trastornos de la conducta alimentaria como factor de riesgo para osteoporosis

... Eating disorders (TCA per its abbreviation in Spanish) are common in young women, with an estimated prevalence of 4-5%. One of the physical complications of eating disorders, especially anorexia nervosa (AN) and eating ...

11

Mecanismos de las acciones neuroprotectoras inducidas por Insulin like Growth Factor 1 (IGF 1) en animales con deficiencia de esta hormona : efectos de la administración exógena de IGF 1 / Juan Enrique Puche García; [directora Inma Castilla de Cortázar La

Mecanismos de las acciones neuroprotectoras inducidas por Insulin like Growth Factor 1 (IGF 1) en animales con deficiencia de esta hormona : efectos de la administración exógena de IGF 1 / Juan Enrique Puche García; [directora Inma Castilla de Cortázar Larrea]

... La evidencia del importante papel que tienen los radicales libres y los sistemas antioxidantes en el envejecimiento ha llevado a estudiar el posible control sistémico de estas enzimas y, quizás, del envejecimiento. Un ...

182

Factores que influyen en la eficiencia de la técnica de producción in vitro de embriones en pequeños rumiantes

Factores que influyen en la eficiencia de la técnica de producción in vitro de embriones en pequeños rumiantes

... específicamente para fecundar los ovocitos. El mercado actual de embriones producidos in vitro crece rápidamente en el bovino y, sin embargo, es prácticamente inexistente en pequeños rumiantes debido al carácter ...

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