Lupus erythematosus
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TítuloLack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus
... 17. Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S, Lee AT, Chung SA, Ferreira RC, Pant PV, Ballinger DG, Kosoy R, Demirci FY, Kamboh MI, Kao AH, Tian C, Gunnarsson I, Bengtsson AA, Rantapää-Dahlqvist S, ...
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The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis
... Outside the HLA region, interferon (IFN) pathway genes, which encode cytokines with critical modulatory effects on innate and adaptive immunity, have been shown to represent a key component of the genetic network leading ...
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Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility
... Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five ...
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High Throughput Sequencing Reveals Circulating miRNAs as Potential Biomarkers of Kidney Damage in Patients with Systemic Lupus Erythematosus
... Systemic lupus erythematosus is a chronic autoimmune inflammatory disease characterized by a myriad of immunoregulatory abnormalities that lead to injuries of tissues and ...of lupus nephritis is ...
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Evidence of new risk genetic factor to systemic lupus erythematosus: the UBASH3A gene
... The ubiquitin associated and Src-homology 3 (SH3) domain containing A (UBASH3a) is a suppressor of T-cell receptor signaling, underscoring antigen presentation to T-cells as a critical shared mechanism of diseases ...
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Relationship between QT Interval Length and Arterial Stiffness in Systemic Lupus Erythematosus (SLE): A Cross-Sectional Case-Control Study.
... in Lupus Erythematosus National Assessment version of the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) [21] and the Systemic Lupus International Collaborating ...
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Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
... systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial,” Arthritis and Rheumatism, ...
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IL 21 signaling pathway modulation in B lymphocytes by vitamin D in systemic lupus erythematosus
... Systemic Lupus Erythematosus (SLE) is an autoimmune disease, characterized by autoantibodies generation and B lymphocyte activation, with a variety of clinical ...
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Cardiovascular disease in latin american patients with systemic lupus erythematosus: a cross-sectional study and a systematic review
... “Lupus Erythematosus, Systemic,” “Cardiovascular Diseases;” “Latin America,” “Ethnic Groups,” “Brazil,” “Mexico,” “Colombia,” “Chile,” “Cuba,” “Panama,” “Venezuela,” “Bolivia,” “Peru,” “Argentina,” ...
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Association study of genetic variants of pro-inflammatory chemokine and cytokine genes in systemic lupus erythematosus
... 8. Andersen LS, Petersen J, Svenson M, Bendtzen K: Production of IL- 1beta, IL-1 receptor antagonist and IL-10 by mononuclear cells from patients with SLE. Autoimmunity 1999, 30(4):235-242. 9. Lit LC, Wong CK, Tam LS, Li ...
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MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated with Systemic Lupus Erythematosus
... Systemic lupus erythematosus (SLE [OMIM 152700]) is a complex and heterogeneous autoimmune disease with a strong genetic component that is modified by environmental ...
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Analysis of ancestral and functionally relevant CD5 variants in systemic lupus erythematosus patients.
... status. Lupus Nephritis (LN) is defined as clinical and laboratory manifestations that meet ACR criteria (persistent proteinuria and/ or cellular casts including red blood cells [RBCs], hemoglobin, granular, ...
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Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations
... the Lupus Family Registry and Repository (86) at the Oklahoma Medical Research Foundation (OMRF), the Cincinnati Children’s Hospital Medical Center (CCHMC), the University of Texas SouthWestern (UTSW), the Center ...
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PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes
... Funding: This work was supported by grants from the US National Institutes of Health (AR060366, AR053483, AR43814, AR049084, AR002138, AR030692, AR053308, AR057172, AI094377, AI101934, AI082714, AI063274, AI070304, ...
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High ACSL5 transcript levels associate with systemic lupus erythematosus and apoptosis in Jurkat T lymphocytes and peripheral blood cells
... attended the out-patient clinic of the University Hospital Virgen de las Nieves of Granada, Spain, were included (Table 1). Exclusion criteria were less than 1 year of follow-up in our unit. Current clinical assessment ...
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Premisas de la tautología autoinmune en la esclerosis múltiple
... de lupus, se ha demostrado como la administración de análogos de la vitamina D reduce la severidad de la proteinuria, la formación de granulomas y mejora la arteritis renal y la alopecia ...del lupus como ...
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Anticuerpos antifosfolípidos
... The relationship of anti-DNA antibody idiotypes and anticardiolipin antibodies to disease activity in systemic lupus erythematosus.. Weidmann CE, Wallace DJ, Peter JB, Knight PT, Bear M[r] ...
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Lupus erimatoso cutaneo subagudo de adecuada respuesta a hidroxicloroquina(planquinol) (Presentacin de caso clinico)
... Cutaneous lupus erythematosus includes a variety of lupus erythematosus-specific skin lesions that are subdivided into three categories: acute lupus erythematosus, subacute ...
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Epigenetics and autoimmune diseases
... Systemic Lupus Erythematosus. Studies have shown that most lupus-related genes contain at least one miRNA target site for more than hundred ...in lupus T cells ...
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