... of stemcells like Oct-4, Rex-1, and SSEA4 ...HIF-1𝛼, cells proliferation, and stem cell markers could explicate our results and the absence of differentiation under severe hypoxic ...reduce ...
... Mesenchymalstemcells promising role in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor ...marrow ...
... off-target cells (bystander and ascopal effects) [8-11] can be crucial to the effect of radiotherapy [12, ...damaged cells after radiotherapy and surviving tumor cells leads to a reduction in the ...
... of MesenchymalStemCells. These cells are an attractive source for cartilage repair because of their availability to chodrogenic differentiation by progressing sequentially through the ...
... in mesenchymalstem ...young mesenchymalstemcells (MSCs) is influenced by their autophagy capacity to regulate the good levels of oncogenic factors like p53 and inflammatory signals ...
... FIGURE 2. Cartilage quality improvement resulting from MSC treatment. Cartilage quality was assessed by MRI T2 mapping and is quantified as the PCI (computed as the percentage of sample points with a T2 relaxation value ...
... context, stem cell-based therapy represents a novel alternative to attenuate radiation-induced brain injury (Acharya et ...neural stemcells (NSCs), which were injected via tail vein 24 h after ...
... [17]. Mesenchymalstemcells (MSCs) are considered to be a promising candidate for cartilage regeneration, due to their ability to differentiate towards cartilage and bone cells and secrete ...
... of mesenchymal and hematopoietic markers in hAMSCs isolated using both ...amniotic cells by immunofluorescence was performed using the antibody FITC- CD44 (IM7 clone; BD ...
... The protein expression profile of MSCs may reveal potential hazards associated with senescence and tumoral transformation that may occur during culture. Proteomic is a valuable tool for human MSC characterization ...
... that cells isolated from gingival tissue under culture conditions exhibited a spindle-shaped fibroblast appearance, similar to bone marrow-derived MSC (BMSC) the cells adhered to the surface of tissue ...
... of cells labelled with different dyes and ...candidate cells for the treatment of arthritic joint diseases both as a struc- tural substitute and as a stand-alone cell therapy or as a combination thereof[17, ...
... Spheroids engineered from MSCs following their differentiation into chondrocyte-like cells were frozen in OCT embedding matrix (BDH Chemicals, Poole, UK). Full-depth sections (4 μm) were cut with a cryostat and ...
... Limbal stem cell deficiency-related symptoms and their impact on daily life activities were evaluated with three self-administered questionnaires. The Single Item Dry Eye Questionnaire (SIDEQ) gives a 0-4 score to ...
... mimic mesenchymal condensation and cell–cell interactions, MSCs are cultured in high density aggregates (pellet culture) ( Johnstone et ...vitro stem cell differentiation into the chondrogenic ...
... A comparison between placental cells and bone marrow-derived mesenchymalstemcells (BM-MSCs) was the aim of the paper published by Barlow et al. (2008). These authors compared human placenta- ...
... Retinal and optic nerve diseases are degenerative ocular pathologies which lead to irreversible visual loss. Since the advanced therapies availability, cell-based therapies offer a new all-encompassing approach. Advances ...
... tissue. MesenchymalStemCells (MSC) can be isolated from the umbilical cord and bone marrow; however, the behavior of Dental Pulp StemCells (DPSC) has been shown to have a high ...
... The culture conditions used to isolate MSC from the synovium are similar to those used to obtain fibroblastic synoviocytes and are based, in part, on the fact that synoviocytes require more time to attach to the culture ...
... rat cells were inoculated into deminer- alized bone matrix (DBM), chambers made of cylin- ders from bone diaphysis with a capacity of 40 µl in volume (37), and then implanted subdermally into syn- geneic ...