Mesenchymal stem cells
TítuloEffects of severe hypoxia on bone marrow mesenchymal stem cells differentiation potential
... of stem cells like Oct-4, Rex-1, and SSEA4 ...HIF-1𝛼, cells proliferation, and stem cell markers could explicate our results and the absence of differentiation under severe hypoxic ...reduce ...
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TítuloInfluence of age on rat bone marrow mesenchymal stem cells potential
... Mesenchymal stem cells promising role in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor ...marrow ...
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Human mesenchymal stem cells enhance the systemic effects of radiotherapy.
... off-target cells (bystander and ascopal effects) [8-11] can be crucial to the effect of radiotherapy [12, ...damaged cells after radiotherapy and surviving tumor cells leads to a reduction in the ...
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Chondrogenic Differentiation of Bone Marrow Mesenchymal Stem Cells First Successful Latin American Report
... of Mesenchymal Stem Cells. These cells are an attractive source for cartilage repair because of their availability to chodrogenic differentiation by progressing sequentially through the ...
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TítuloEffect of aging on behaviour of mesenchymal stem cells
... in mesenchymal stem ...young mesenchymal stem cells (MSCs) is influenced by their autophagy capacity to regulate the good levels of oncogenic factors like p53 and inflammatory signals ...
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Treatment of Knee Osteoarthritis with Autologous Mesenchymal Stem Cells: A Pilot Study
... FIGURE 2. Cartilage quality improvement resulting from MSC treatment. Cartilage quality was assessed by MRI T2 mapping and is quantified as the PCI (computed as the percentage of sample points with a T2 relaxation value ...
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Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy
... context, stem cell-based therapy represents a novel alternative to attenuate radiation-induced brain injury (Acharya et ...neural stem cells (NSCs), which were injected via tail vein 24 h after ...
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Adipose derived mesenchymal stem cells : are they a good therapeutic strategy for osteoarthritis? / Elena Damiá, Deborah Chicharro, Sergio López, Belén Cuervo, Mónica Rubio, Joaquín Sopena, José Manuel Vilar and José María Carrillo
... [17]. Mesenchymal stem cells (MSCs) are considered to be a promising candidate for cartilage regeneration, due to their ability to differentiate towards cartilage and bone cells and secrete ...
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TítuloIsolation and characterization of mesenchymal stem cells from human amniotic membrane
... of mesenchymal and hematopoietic markers in hAMSCs isolated using both ...amniotic cells by immunofluorescence was performed using the antibody FITC- CD44 (IM7 clone; BD ...
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TítuloProteomic applications in the study of human mesenchymal stem cells
... The protein expression profile of MSCs may reveal potential hazards associated with senescence and tumoral transformation that may occur during culture. Proteomic is a valuable tool for human MSC characterization ...
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MatrigelBD, A Biocompatible Scaffold that Improves Gingival Mesenchymal Stem Cells Proliferation.
... that cells isolated from gingival tissue under culture conditions exhibited a spindle-shaped fibroblast appearance, similar to bone marrow-derived MSC (BMSC) the cells adhered to the surface of tissue ...
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TítuloCD105+ mesenchymal stem cells migrate into osteoarthritis joint: an animal model
... of cells labelled with different dyes and ...candidate cells for the treatment of arthritic joint diseases both as a struc- tural substitute and as a stand-alone cell therapy or as a combination thereof[17, ...
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TítuloLamin A deregulation in human mesenchymal stem cells promotes an impairment in their chondrogenic potential and imbalance in their response to oxidative stress
... Spheroids engineered from MSCs following their differentiation into chondrocyte-like cells were frozen in OCT embedding matrix (BDH Chemicals, Poole, UK). Full-depth sections (4 μm) were cut with a cryostat and ...
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A proof of concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency
... Limbal stem cell deficiency-related symptoms and their impact on daily life activities were evaluated with three self-administered questionnaires. The Single Item Dry Eye Questionnaire (SIDEQ) gives a 0-4 score to ...
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TítuloMolecular profile and cellular characterization of human bone marrow mesenchymal stem cells: donor influence on chondrogenesis
... mimic mesenchymal condensation and cell–cell interactions, MSCs are cultured in high density aggregates (pellet culture) ( Johnstone et ...vitro stem cell differentiation into the chondrogenic ...
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TítuloHuman amniotic membrane as an alternative source of stem cells for regenerative medicine
... A comparison between placental cells and bone marrow-derived mesenchymal stem cells (BM-MSCs) was the aim of the paper published by Barlow et al. (2008). These authors compared human placenta- ...
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Mesenchymal stem cell therapy in retinal and optic nerve diseases: An update of clinical trials
... Retinal and optic nerve diseases are degenerative ocular pathologies which lead to irreversible visual loss. Since the advanced therapies availability, cell-based therapies offer a new all-encompassing approach. Advances ...
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Comportamiento de clulas mesenquimales obtenidas de tejidos dentales: Revisin de literatura
... tissue. Mesenchymal Stem Cells (MSC) can be isolated from the umbilical cord and bone marrow; however, the behavior of Dental Pulp Stem Cells (DPSC) has been shown to have a high ...
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TítuloQuantification of cells expressing mesenchymal stem cell markers in healthy and osteoarthritic synovial membranes
... The culture conditions used to isolate MSC from the synovium are similar to those used to obtain fibroblastic synoviocytes and are based, in part, on the fact that synoviocytes require more time to attach to the culture ...
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Characterization of Adult Stem/Progenitor Cell Populations From Bone Marrow in a Three-Dimensional Collagen Gel Culture System.
... rat cells were inoculated into deminer- alized bone matrix (DBM), chambers made of cylin- ders from bone diaphysis with a capacity of 40 µl in volume (37), and then implanted subdermally into syn- geneic ...
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