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metronomic chemotherapy

Metronomic chemotherapy: changing the paradigm that more is better

Metronomic chemotherapy: changing the paradigm that more is better

... “metronomic chemotherapy” has been pro- ...of metronomic chemotherapy, plus the increasing experience that is being obtained in the clinical setting, will help to lead a change in the design ...

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The Immune Response and the Therapeutic Effect of Metronomic Chemotherapy With Cyclophosphamide

The Immune Response and the Therapeutic Effect of Metronomic Chemotherapy With Cyclophosphamide

... Metronomic chemotherapy (MCT) is a novel therapeutic strategy for cancer treatment endowed with an antiangiogenic effect. It refers to regular administration of low doses of cytotoxic drugs, with minimal or ...

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Therapeutic efficacy of metronomic chemotherapy with cyclophosphamide and doxorubicin on murine mammary adenocarcinomas

Therapeutic efficacy of metronomic chemotherapy with cyclophosphamide and doxorubicin on murine mammary adenocarcinomas

... Metronomic chemotherapy (MCT) involves the chronic administration of doses of chemotherapy drugs that are below the maximum tolerated dose (MTD), at frequent and regular intervals, without extended ...

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Safety and therapeutic effect of metronomic chemotherapy with cyclophosphamide and celecoxib in advanced breast cancer patients

Safety and therapeutic effect of metronomic chemotherapy with cyclophosphamide and celecoxib in advanced breast cancer patients

... Metronomic chemotherapy (MCT), the chronic administration, at regular intervals, of low doses of chemotherapeutic drugs, without extended rest periods, allows chronic treatment with therapeutic efficacy and ...

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Comparative Effectiveness of Two Metronomic Chemotherapy Schedules  Our Experience in the Preclinical Field

Comparative Effectiveness of Two Metronomic Chemotherapy Schedules Our Experience in the Preclinical Field

... 14. Mainetti L. E., Rozados V. R., Rossa A., Bonfil R. D., Scharovsky O. G. Antitumoral and antimetastatic effects of metronomic chemotherapy with cyclophosphamide combined with celecoxib on murine mammary ...

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Metastatic breast cancer patients treated with low dose metronomic chemotherapy with cyclophosphamide and celecoxib: clinical outcomes and biomarkers of response

Metastatic breast cancer patients treated with low dose metronomic chemotherapy with cyclophosphamide and celecoxib: clinical outcomes and biomarkers of response

... Metronomic chemotherapy (MCT) poses a new paradigm in cancer therapy: “less is more when administered chronically” [3]. The antitumor effect is achieved through an antiangiogenic mechanism demonstrated in ...

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Clinical response in patients with ovarian cancer treated with  metronomic chemotherapy

Clinical response in patients with ovarian cancer treated with metronomic chemotherapy

... the chemotherapy schemes, but also on others factors like response to first line chemotherapy, disease free survival upon surgery, and number of previous treatments ...[22]. Metronomic ...

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Association between baseline VEGF/sVEGFR 2 and VEGF/TSP 1 ratios and response to metronomic chemotherapy using cyclophosphamide and celecoxib in patients with advanced breast cancer

Association between baseline VEGF/sVEGFR 2 and VEGF/TSP 1 ratios and response to metronomic chemotherapy using cyclophosphamide and celecoxib in patients with advanced breast cancer

... BACKGROUND: Metronomic chemotherapy (MCT) with cyclophosphamide (Cy) and celecoxib (Cel) has therapeutic efficacy and low toxicity profile in advanced breast cancer patients (ABCP), but no reliable ...

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Lessons from the Fourth Metronomic and Anti angiogenic Therapy Meeting, 24–25 June 2014, Milan

Lessons from the Fourth Metronomic and Anti angiogenic Therapy Meeting, 24–25 June 2014, Milan

... of metronomic cyclophosphamide plus capecitabine and bevacizumab whereas the standard arm consisted of weekly paclitaxel plus ...the metronomic cyclophosphamide plus UFT regimen in combination with ...

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Metronomic therapy with cyclophosphamide induces rat lymphoma and sarcoma regression, and is devoid of toxicity

Metronomic therapy with cyclophosphamide induces rat lymphoma and sarcoma regression, and is devoid of toxicity

... treatment. The novel component comprised a cell target switch, which now aims towards the genetically stable tumour endothelial cells, along with a change in the schedule and dose of drug administration, thereby ...

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Cholestatic hepatitis C after chemotherapy containing rituximab in diffuse large B cell lymphoma

Cholestatic hepatitis C after chemotherapy containing rituximab in diffuse large B cell lymphoma

... month of treatment, HCV RNA level decreased to 1,810 IU/mL (reduction of 4.96 log 10 ), but there was only a slight reduction in cholestasis (GGT, x15 nv; bilirubin, x10 nv; ALP, x10 nv). The patient contin- ued the ...

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Globe salvage with intra arterial topotecan melphalan chemotherapy in children with a single eye

Globe salvage with intra arterial topotecan melphalan chemotherapy in children with a single eye

... artery chemotherapy for retinoblastoma in children : 3-years Lausanne ...intra-arterial chemotherapy using simultaneous carbopla- tin, topotecan and melphalan for intraocular retinoblastoma: preliminary ...

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Askin tumor: Case report and literature review

Askin tumor: Case report and literature review

... neoadjuvant chemotherapy in association with surgical resection and/or postoperative radiotherapy, with which a decreased local recurrence and a greater disease- free period can be ...

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Eficacia de la radioterapia y la quimioterapia combinadas comparada con la radioterapia en el carcinoma oral de clulas escamosas

Eficacia de la radioterapia y la quimioterapia combinadas comparada con la radioterapia en el carcinoma oral de clulas escamosas

... Two reviewers assessed all articles that met the selection criteria, methodological quality and factors of the clinical process. Each included investigation they read for the topics: randomization, blinding and bias. It ...

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Melatonin induced oncostasis, mechanisms and clinical relevance

Melatonin induced oncostasis, mechanisms and clinical relevance

... 1997 A randomized study of chemotherapy with cisplatin plus etoposide versus chemoendocrine therapy with cisplatin, etoposide and the pineal hormone melatonin as a first-line treatment o[r] ...

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Patterns of bacterial resistance in urinary isolates at a public health care center

Patterns of bacterial resistance in urinary isolates at a public health care center

... Trends in Antimicrobial Resistance among Urinary Tract Infection Isolates of Escherichia coli from Female Outpatients in the United States.. Antimicrobial Agents and Chemotherapy.[r] ...

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Thymosin β10 as a predictive biomarker of response to 5 fluorouracil chemotherapy in cholangiocarcinoma

Thymosin β10 as a predictive biomarker of response to 5 fluorouracil chemotherapy in cholangiocarcinoma

... CCAs are heterogenous cancers with a very poor prog- nosis. Adjuvant therapy is widely recommended for post- operative patients who have positive margins or those who have had a complete resection but with node-positives ...

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Circulating Tumor Cells Following First Chemotherapy Cycle: An Early and Strong Predictor of Outcome in Patients With Metastatic Breast Cancer

Circulating Tumor Cells Following First Chemotherapy Cycle: An Early and Strong Predictor of Outcome in Patients With Metastatic Breast Cancer

... a chemotherapy regimen in patients with metastatic breast ...of chemotherapy is an early, and strong, predictor of treatment outcome in MBC patients, since it can identify those patients who derive little ...

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Efecto del immunepotent CRP en la respuesta clínica e inmunológica en pacientes con cáncer de mama.

Efecto del immunepotent CRP en la respuesta clínica e inmunológica en pacientes con cáncer de mama.

... Evaluation of the immunologic response. the immunologic parameters of the patients were monitored during chemo- therapy in both groups. in addition, in the group that received bdlE as adjuvant the cellular immune ...

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