Mitochondrial biogenesis
Papel del receptor a estrógenos GPER en los efectos de la (-)-epicatequina sobre la biogénesis mitocondrial en células C2C12Role of estrogen receptor GPER in the effects of (-)-Epicatechin on mitochondrial biogenesis in C2C12 myotubes
... SkM mitochondrial function and biogenesis (MB, synthesis of new ...by mitochondrial staining with MitoTracker® Green and quantification of protein levels of complex II, IV and nuclear respiratory ...
64
Physical Exercise and Mitochondrial Disease: Insights From a Mouse Model
... in mitochondrial content or mitochondrial biogenesis, through the activation of peroxisome proliferator-activated receptor gamma co-activator 1-alpha (PGC-1 α ) might be a therapeutic option (8, ...
10
Canonical Wnt signaling protects hippocampal neurons from A beta oligomers: role of non canonical Wnt 5a/Ca2+ in mitochondrial dynamics
... enhances mitochondrial biogenesis through Insulin recep- tor substrate-1 (IRS-1) producing, as a consequence, an increase of reactive oxygen species (ROS) levels and oxidative damage in non-neuronal cells ...
12
Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin expressing cells Possible role of peroxisome proliferator activated receptor gamma (PPAR gamma) in the pathogenesis of Huntington disease
... increase mitochondrial function (23, ...induced mitochondrial biogenesis in mouse brain ...duced mitochondrial dysfunction (5, 6, ...potential, mitochondrial calcium deregulation, and ...
11
Melatonin and mitochondrial dysfunction in the central nervous system
... preventing mitochondrial lysine hyperacetylation (Lombard et ...stimulate mitochondrial biogenesis (Guarente, ...that mitochondrial biogenesis might be stimulated by the methoyindole in ...
28
Efecte modulador de la leptina i polifenols en la funció mitocondrial i metabolisme de la cèl·lula tumoral
... in mitochondrial volume and mitochondrial respiratory chain components [Singh et ...modulate mitochondrial metabolism in different ...suppressing mitochondrial respiration in ...higher ...
175
Peroxisome proliferator activated receptor (PPAR) ã and PPARá agonists modulate mitochondrial fusion fission dynamics: Relevance to reactive oxygen species (ROS) related neurodegenerative disorders
... were washed and labeled with 50 nM Mitotracker Red (Molecular Probes) for 30 min at 37uC. Cells were then fixed by paraformal- dehyde-sucrose 4% fixative and permeabilized with PBS-Triton X 0.01%. Hippocampal neurons ...
10
Modulation of mitochondrial Ca2+ uptake by estrogen receptor agonists and antagonists
... The classic pathway for estrogen action occurs in the nucleus, where ERs bind to estrogen-responsive elements in DNA to activate transcription ofa series oftarget genes (Beato & Klug, 2000). This pathway requires ...
10
Characterizing the role of mitochondrial Ca2+ overload and permeability transition during the BCR dependent activation of murine B lymphocytes
... on mitochondrial carbon oxidation, allowing for increased export of citrate into cytosol and conversion to acetyl-CoA to increase histone acetylation ...a mitochondrial metabolite and that this mechanism is ...
41
Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers
... Our results indicate that disturbed THOC1 and ALY expression are associated with tumorogenesis. Overex- pression of THOC1 has previously been correlated to the grade of invasiveness in breast tumor, and also a ...
11
TítuloThe mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint
... between mitochondrial dysfunction and activation of inflammatory pathways in articular ...of mitochondrial function, induces an oxidative and inflammatory response in rat knee ...and mitochondrial ...
12
Diets based on virgin olive oil or fish oil but not on sunflower oil prevent age-related alveolar bone resorption by mitochondrial-related mechanisms.
... The development of interventions to retard the aging process, focused on extending maximum life span and/or retarding the broad spectrum of age-associated biological changes, is of great importance. To date, in ...
11
Mitochondrial free [Ca2+] levels and the permeability transition
... of mitochondrial membranes. Fig. 5 shows that we can in fact trig- ger the opening of PTP using the widely used PTP-opener phenyl arsine oxide (PAO). This oxidant is known to induce the perme- ability transition ...
9
La maquinaria de biognesis de los microRNAs: regulacin por hormonas esteroideas y alteraciones en el cncer
... microRNA biogenesis machinery components have hormonal response el- ements in specific genomic regions (as the gene pro- moter) and an induction in their expression may contribute to an induction in microRNA ...
5
TítuloAnalysis of mitochondrial proteins in the surviving myocardium after ischemia identifies mitochondrial pyruvate carrier expression as possible mediator of tissue
... MS/MS peak lists were generated by extract_msn.exe and matched to a combined pig and human database (UniProtKB/Swiss-Prot release 2015_02, February 4, 2015, 93,943 protein entries) using Mascot (version 2.3.01, Matrix ...
14
Are nuclear insertions of mitochondrial origin pseudogenes?
... with mitochondrial genes and are classified as pseudogenes due to its different genomic code, but in the following section we compare this information with GTEx data to elucidate if all of them are pseudogenes or ...
83
Trimetazidine prevents palmitate induced mitochondrial fission and dysfunction in cultured cardiomyocytes
... analyzed mitochondrial morphol- ogy and ...marked mitochondrial fission ...altered mitochondrial morphology ...increased mitochondrial fission through DRP-1 activity ...assessing ...
14
EL TRATAMIENTO CON EL ANTICUERPO ANTI-PROTEOGLICANO CHP3R99 NO AFECTA LA BIOENERGÉTICA MITOCONDRIAL EN RATONES / The anti-proteoglycan antibody chP3R99 treatment does not affect mitochondrial bioenergetic in mice
... Nowadays, mitochondrial energy metabolism is recognized as the most quantitatively important source of ROS in the majority of eukaryotic cell ...of mitochondrial ROS generation occurs at the electron ...
14
Melatonin in mitochondrial dysfunction and related disorders
... a mitochondrial subform of iNOS (mt iNOS) activity was examined in liver and lung mitochondria of rats ...the mitochondrial failure that occurs during endotoxemia were more pronounced in older animals than ...
17
CFTR activity and mitochondrial function
... the mitochondrial abnormalities found in CF cells or ...regulating mitochondrial functions, in particular de OXPHOS pathway, and the role of mitochondria in modulating the inflammatory process, and their ...
13