Prostate Cancer
A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
... 15. Hunter DJ, Riboli E, Haiman CA, Albanes D, Altshuler D, Chanock SJ, Haynes RB, Henderson BE, Kaaks R, Stram DO, Thomas G, Thun MJ, Blanche´ H, Buring JE, Burtt NP, Calle EE, Cann H, Canzian F, Chen YC, Colditz GA, ...
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Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC)
... It is more difficult to understand the association between rs4955720 and decreased risk of prostate cancer from a biological point of view. However, in the joint analysis the p value of this SNP was the ...
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Glycan alterations of serum proteins as tumour markers. Prostate-specific antigen in prostate cancer and acute-phase proteins in pancreatic cancer
... Prostate-specific antigen (PSA) two-dimensional electrophoresis (2-DE) subforms (F1–F5) have been described to be altered in prostate cancer (PCa) compared to benign prostatic hyperplasia (BPH). To ...
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TítuloRadium 223 dichloride: a new paradigm in the treatment of prostate cancer
... for prostate cancer), 153 Sm-lexidronam (153Sm- EDTMP; approved in Europe for osteoblastic metastases) and 186Re-etidronate (186Re- HEDP; approved in some European countries) have been available for pain ...
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An understanding of the prostate cancer pathophysiology for identification of biomarkers that support an early diagnosis
... Abstract Prostate specific antigen and digital rectal examination are diagnostic tools that currently fall short when differentiating between malignant processes, such as prostate can- cer and benign ...
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TítuloCyclooxygenase 2 (COX 2): a molecular target in prostate cancer
... There is also recent evidence that microtubule-interfering agents, including taxanes, stimulate COX-2 transcription [61]. This could modify the efficacy of this class of drugs. Thus, coadministration of a selective COX-2 ...
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Mediterranean diet adherence and prostate cancer risk.
... The search for articles came from extensive research in the following databases: PubMed, Scopus and Web of Science. We used the search terms “Mediterranean diet”, “adherence”, “fruit and vegetable“, “olive oil“, “fish” ...
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TítuloRole of taxanes in advanced prostate cancer
... Advanced prostate cancer is an androgen-dependent disease for which the initial treatment is an androgen deprivation maneuver. However, some primary resistances to hormonal treatment occur with increasing ...
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Prognostic role of genetic biomarkers in clinical progression of prostate cancer.
... for prostate cancer (PCa) detection and progression, as well as perform a genetic classi fi cation of high-risk ...(stage, prostate-speci fi c antigen, Gleason score and progression) in patients and ...
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Prevention and treatment of osteoporosis in prostate cancer Recommendations
... of prostate cancers, particularly in androgen deprivation therapy for prostate cancer, are associated with significant bone loss and with an increase in fracture ...
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Depression promotes prostate cancer invasion and metastasis via a sympathetic cAMP FAK signaling pathway
... into prostate cancer provided new evidence for the active role of nerve in tumor ...in prostate [6] and the other in gastric [43] cancers, have demonstrated the direct stimulating role of nerves in ...
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Androgen responsive SRF target genes regulate prostate cancer cell migration
... Progression of prostate cancer (CaP) relies on androgen recep- tor (AR) signaling, but AR-dependent events that underlie the lethal phenotype remain unknown. Recently, an indirect mechanism of androgen ...
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TítuloTissue scale, patient specific modeling and simulation of prostate cancer growth
... the prostate of the patient under consideration (see Section ...the prostate, its geometry evolves toward a structure consisting of thickened layers of cancerous tissue with fingered protrusions along the ...
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TítuloEnzalutamide: a new prostate cancer targeted therapy against the androgen receptor
... Enzalutamide (MDV3100), an androgen receptor-signalling inhibitor, represents the most recent compound added to the therapeutic armamentarium for the treatment of metastatic castration-resistant prostate ...
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Intensity modulated radiotherapy versus radical prostatectomy in patients with localized prostate cancer: long term follow up
... As for RP, surgical techniques have been added, such as the preservation of the neurovascular bundles and la- paroscopy or robotic surgery to improve outcomes and de- crease complications. Radiotherapy has advanced ...
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Analisis de la expresión y la función del receptor sensor de calcio en tumores del desarrollo
... The CaSR is a family C G-protein coupled receptor (GPCR) whose primary role is to regulate the secretion of parathyroid hormone to maintain calcium plasmatic concentrations within a very narrow range (15). The CaSR is ...
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Biopsias prostáticas, ¿Hasta cuándo biopsiar?
... ( prostate-specific antigen , PSA) total, tacto rectal, relación PSA libre/total, PSA más densidad, PSA más velocidad, PCA3, 4Kscore®, ...el Prostate Cancer Risk calculator , a fin de restarle ...
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Do socioeconomic inequalities in mortality vary between different Spanish cities? a pooled cross-sectional analysis.
... (men: prostate cancer, diabetes, mental illnesses, Alzheimer ’ s disease, cerebrovascular disease; women: diabetes, mental illnesses, respiratory diseases, cirrhosis) no differences were found between ...
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Prevalence of diabetes in a cancer population in a Malaga hospital.
... of cancer patients 48 hours after the hospital admission, concluding that a prevalence of overweight is observed in population over 45 years, in both healthy subjects and those with ...in cancer patients ...
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TNF α/IL 1/NF κB transduction pathway in human cancer prostate
... for cancer therapy. However, its role in the treatment of cancer patients is debated (Bertazza and Mocellin, ...for cancer prostate and the use of vaccination with different antigens such as ...
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