Ras/MAPK signaling pathway
Signaling pathways involved in colorectal cancer progression
... these signaling pathways in ...of Ras exist more in B-RafD594G mutant CRCs, rather than B-RafV600E mutant ...ERK–MAPK pathway in CRC, upregulation of the EGFR is a potential mecha- nism ...
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Bases moleculares de la especificación del patrón dorso-ventral en Drosophila
... RTK signaling pathway is the Ras/MAPK pathway, which is highly conserved in eukaryotes and controls multiple developmental processes (Figure ...1). Ras/MAPK ...
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Función del Represor Capicua en la Interpretación de Señales RTK-Ras-MAPK en "Drosophila"
... RTK/Ras/MAPK signaling pathways play key functions in metazoan development, but how they control expression of downstream genes is not well ...RTK signaling in different ...RTK pathway ...
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Molecular Markers in Thyroid Cancer
... and RAS genes (KRAS, HRAS, NRAS) as well as RET- PTC and receptor tyrosine kinases (TRK) rear- rangements, all of which are able to activate the MAPK pathway are found in papillary thyroid carcinoma ...
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Regulation of Placental Leptin Expression by Cyclic Adenosine 5 '-Monophosphate Involves Cross Talk between Protein Kinase A and Mitogen-Activated Protein Kinase Signaling Pathways
... cAMP/PKA pathway and the MAPK cascades mod- ulate common processes in the cell and multiple levels of cross talk between these signaling pathways have been de- scribed (85– ...1/2 pathway, ...
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Depression promotes prostate cancer invasion and metastasis via a sympathetic cAMP FAK signaling pathway
... glucocorticoid signaling pathways, exhibit dysregulation in the tumors of lethal prostate cancer in comparison with nonlethal prostate cancer ...neuroendocrine signaling in depression are critical for ...
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Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20 APP transgenic and wild type mice
... Wnt signaling is necessary for hippocampal memory consolidation (Fortress et ...Wnt Signaling is decreased (Selkoe et ...Wnt signaling affects cognitive abilities and hippocampal function in J20 Tg ...
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Wnt signaling in the regulation of adult hippocampal neurogenesis
... the signaling molecules present in the local microenvi- ...Wnt signaling pathway, which may mimic what is observed in hippocampal neurons (Varela-Nallar et ...
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Dipeptidyl peptidase IV and its implication in cancer Yarini M Arrebola , Hansel Gmez , Pedro A Valiente , Mara de los A Chvez , Isel Pascual
... 115. Christopherson KW, 2nd, Hangoc G, Broxmeyer HE. Cell surface peptidase CD26 dipeptidylpeptidase IV regulates CXCL12/ stromal cell-derived factor-1 alpha-mediated chemotaxis of human cord blood CD34+ pro- genitor ...
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Gene Expression Profiling in Limb-Girdle Muscular Dystrophy 2A
... However, the final list of genes comprised 86 probe sets (74 genes) commonly yielded by the two methodologies which were differentially expressed in LGMD2A compared to unaffected muscle biopsies. Of these 74 genes, 53 ...
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FGF-1 reverts epithelial-mesenchymal transition induced by TGF-beta 1 through MAPK/ERK kinase pathway
... TGF-  1, a potent profibrotic factor, plays a pivotal role promoting EMT in normal development and in pathological processes, including the alveolar epithelial cell transition to myofibroblasts in vitro and in vivo (1, ...
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Involvement of WNT signaling pathway in the adult hippocampal synapses :role in neuroprotection
... Wnt pathway has a protective effect against cytotoxic damage caused by exposure to Aβ (Cerpa et ...Wnt/JNK signaling, prevents both synaptic transmission depression and loss of PSD-95 induced by Aβ ...
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Estudio de la regulación post-transcripcional de genes mediada por microRNA en pacientes con colitis ulcerosa tratados con glucocorticoides
... KEGG 04010: MAPK signaling pathway KEGG 04510: Focal adhesion KEGG 05200: Pathways in cancer KEGG 04810: Regulation of actin cytoskeleton KEGG 04722: Neurotrophin signaling pathway KEGG [r] ...
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Calcium/Calmodulin Dependent Protein Kinase Type IV Is a Target Gene of the Wnt/beta Catenin Signaling Pathway
... transcriptional pathway through the phosphorylation of CREB (Cohen and Greenberg, ...Wnt signaling, as in the neuroprotection observed against Ab peptide (Alvarez et ...Wnt signaling pathway ...
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Expression and activation of intracellular receptors TLR7, TLR8 and TLR9 in peripheral blood monocytes from HIV infected patients
... tients and controls, so that the results obtained from the determi- nation of TLR expressions and activation of the signaling pathway were not influenced by an alteration in the population of inter- est. ...
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Epigenetic Mechanisms in Cognition
... ERK pathway in all cells is regulation of gene expression, and studies of the role of ERK signaling in synaptic plasticity, memory formation, drug addic- tion, and circadian rhythms have borne this out in ...
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Deletion of diacylglycerol responsive TRPC genes attenuates diabetic nephropathy by inhibiting activation of the TGFβ1 signaling pathway
... Because previous studies had shown that a gain-of-function mutation in TRPC6 is associ- ated with the onset of focal segmental glomer- ulosclerosis (FSGS) [4, 5], efforts of numerous research groups have been focused on ...
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Special Topic: NF- κB, Immunity and Cancer NF- κB Signaling Pathway and Its Therapeutic Implications in Human Diseases
... NF-κB signaling is constitutively activated via an au- tocrine loop induced by chemokines, cytokines and their respective re- ceptors, leading to the differentiation of macrophages, granulocytes, T and B cells, as ...
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WNT signaling in neuronal maturation and synaptogenesis
... Wnt3a increase the number of presynaptic puncta suggesting a role for these ligands in presynaptic assembly (Ahmad-Annuar et al., 2006; Cerpa et al., 2008; Davis et al., 2008). Wnt7a also increases the clustering of ...
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