Skeletal muscle
Inhibition of the angiotensin converting enzyme decreases skeletal muscle fibrosis in dystrophic mice by a diminution in the expression and activity of connective tissue growth factor (CTGF/CCN 2)
... the skeletal muscle fibrosis associated with DMD (Cabello-Verrugio et ...in skeletal muscle and are elevated in dystrophic skeletal muscle (Cabello-Verrugio et ...dystrophic ...
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A Novel Mechanism of Sequestering FGF 2 by Glypican in Lipid Rafts, Allowing Skeletal Muscle Differentiation
... Glypican-1 is required for successful skeletal muscle differ- entiation. To evaluate the role of glypican-1 during myogen- esis, we studied the effect of its absence in this process. By lentiviral infection ...
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High Fat Diet Induced Skeletal Muscle Wasting Is Decreased by Mesenchymal Stem Cells Administration: Implications on Oxidative Stress, Ubiquitin Proteasome Pathway Activation, and Myonuclear Apoptosis
... to skeletal muscle atrophy, a pathological condition characterized by the loss of strength and muscle ...of muscle atrophy is a decrease of myofibrillar proteins as a result of ubiquitin ...
14
Genetic engineering of the skeletal muscle to counteract insulin resistance and obesity
... the skeletal muscle, this suggests that the skeletal muscles expressing Gck remained insulin sensitive, probably contributing to the observed prevention in systemic insulin ...the skeletal ...
191
Role of proteoglycans in the regulation of the skeletal muscle fibrotic response
... in skeletal muscle both in vitro and in ...the skeletal muscle from dystrophic dogs [24] and mdx mice ...in skeletal muscle biopsies from DMD patients ...extensive ...
9
TGF beta receptors, in a Smad independent manner, are required for terminal skeletal muscle differentiation
... β -RI activity is essential for this increase, since SB 431452 inhibits the induction of myosin during skeletal muscle differentiation. The reduction of Smad-2 by its silence is shown in the same figure. ...
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Fast-Twitch Glycolytic Skeletal Muscle Is Predisposed to Age-Induced Impairments in Mitochondrial Function
... in skeletal muscle (49) producing atypi- cal and individual organelles through unregulated means ...saponin-permeabilized skeletal muscle ...to skeletal muscle mitochondria while ...
13
Angiotensin (1 7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas
... normal muscle, insulin-like growth factor-1 (IGF-1), via IGFR-1, activates protein kinase B (Akt), resulting in p70S6 kinase ( p70S6K) phosphorylation and ...During muscle atrophy, activity of the IGF-1/Akt ...
9
Acute electrical stimulation modifies cross-sectional area and desmin protein in the skeletal muscle of old rats submitted to hindlimb suspension
... adult muscle is the desmin protein (470 amino acids) ...in skeletal, cardiac and smooth muscles, being more abundant in cardiac muscle (2% of total protein) that in the skeletal muscle ...
13
Transforming growth factor type beta 1 increases the expression of angiotensin II receptor type 2 by a SMAD and p38 MAPK dependent mechanism in skeletal muscle
... in skeletal mus- cle induces an increase in AT-2 without changes in ...dystrophic skeletal muscle from mdx mice, AT-1 levels remain unchanged, whereas AT-2 levels are aug- mented compared with normal ...
10
Greater basal skeletal muscle AMPKalpha phosphorylation in men than in women: associations with anaerobic performance
... basal skeletal muscle signalling cascades regulating muscle ...Design: Muscle biopsies were obtained from 25 men and 10 women all young and ...summary, skeletal muscle basal AMPK ...
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Role of skeletal muscle proteoglycans during myogenesis
... during skeletal muscle formation, adult muscle regeneration and they are also associated with acute and chronic muscle ...in skeletal muscle repair asso- ciated with ...
9
Wnt signaling in skeletal muscle dynamics: Myogenesis, neuromuscular synapse and fibrosis
... in muscle regeneration that culminates with a decrease in muscle activity [13, ...promotes muscle fibrosis [13, ...that muscle fibers rely in calcium for most of their functions, we will also ...
16
ATP Released by Electrical Stimuli Elicits Calcium Transients and Gene Expression in Skeletal Muscle
... mRNA Determinations—Total RNA from rat skeletal myo- tubes was extracted with TRIzol 威 reagent (42). The reverse transcription (RT) reaction was performed with 1 g of total RNA using an oligo(dT) primer. PCR was ...
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Inflamatory infiltrate in skeletal muscle injected with Bothrops asper venom
... This pattern of inflammatory infiltrate composition is partially different from the ones observed in other examples of myonecrosis. For instance , in muscle damage induced by the local anesthetic bupivacaine and ...
6
Post-exercise effects of graduated compression garment use on skeletal muscle recovery and delayed onset muscle soreness: a systematic review
... increases muscle arterial blood flow and subsequent recovery (Chatard et ...affect muscle blood flow (creating a mechanical obstacle to circulation) not only on the surface but also in the deeper parts of ...
9
Peroxisome proliferator-cctivated receptor targets for the treatment of metabolic diseases
... causes suppression of insulin action and promotes insulin resistance. In particular, PPAR-𝛾 appears to be associated with genes involved in FA transport, lipid droplet formation, and TAG synthesis and breakdown. ...
19
Estrès del reticle endoplasmàtic, inflamació i resistència a la insulina en cèl•lules musculars esquelètiques
... human skeletal muscle cellsTo evaluate the effects of PPARβ/δ activation on palmitate-induced ER stress in skeletal muscle cells we first examined the effects of GW501516, a selective ligand ...
218
Human somatic cells acquire the plasticity to generate embryoid like metamorphosis via the actin cytoskeleton in injured tissues
... From the Department of Pathology, Depart- mental Hospital of Villavicencio, we collected sixty (60) surgical specimens from tissues with severe acute injuries. Mesodermal origin: Tw- enty (20) trauma lower-limb ...
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Texto Recomendado
... Abnormal gas transport within the vascular system creates a different group of pulmonary pathophysiolo- gies. The low solubility of oxygen is offset by the pres- ence of oxygen carrying proteins, such as hemoglobin in ...
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