Somatic Mutations
Mechanisms of chemoresistance and miRNA regulation in myeloid hematologic malignancies
... This overexpression or constitutive activation and the subsequent increase in the antioxidant defense in lung cancer cells are mainly consequences of somatic mutations in the Nrf2 and Ke[r] ...
273
Whole Sequencing of the Mitochondrial Genome of Breast Cancer Tissue in Mexican Mestizo Postmenopausal Women with Different Body Mass Index
... To the best of our knowledge, this is the first report where the complete sequence of mtDNA in Mexican- Mestizo postmenopausal women with breast cancer and different BMI is performed, using human micro- array data from ...
9
Impact of NGS in the medical sciences: genetic syndromes with an increased risk of developing cancer as an example of the use of new technologies
... PTEN mutations are responsible for the pathogenesis of the PTEN hamartoma tumor syndromes (PHTS) that are characterized by overgrowth and multiple ...Activating mutations in the AKT1 gene that are likely ...
9
Lack of evidence for KRAS oncogenic mutations in triple-negative breast cancer.
... cancer-related somatic mutations in codons 12 and 13 of human KRAS ...oncogenic mutations, indicat- ing that the full set of 35 triple-negative tumors expressed the wild-type protein (Table 2 and ...
9
TítuloPOT1 and damage response malfunction trigger acquisition of somatic activating mutations in the VEGF pathway in cardiac angiosarcomas
... acquired somatic mutations in the VEGF-angiogenesis path- way that drive angiosarcoma ...uncovered somatic angiogenesis activation in tumors other than cardiac ...of somatic mutations. ...
34
Mutations in the DNA methylation pathway and number of driver mutations predict response to azacitidine in myelodysplastic syndromes
... of mutations in 34 candidate genes and response to azacitidine in 84 patients with myelodysplastic syndrome (MDS), with 217 somatic mutations identified by next-generation ...of ...
14
Browsing by Title
... Key words: Drosophila rnelanogasfer, genotoxicity, sex-linked recessive lethal test (SLRLT), sex chromosome loss test (SCLT), somatic mutation and recombination test (SMA[r] ...
12
Effect of λ tI point mutations on T3 RNA polymerase mediated transcription termination
... point mutations tI1, tI2 and tI3 were ...tI mutations were cloned into the pBS+ vector for in vitro transcription ...tI mutations map- ping in the tI stem-loop structure decrease the in vitro ...
6
Basic and Clinical Insights in Catecholaminergic (Familial) Polymorphic Ventricular Tachycardia
... missense mutations have been associated with the CPVT phenotype (human gene mutation database; ...missense mutations occur- ring mainly at four hotspots: N-terminal (CPVT1-I, RyR2 residues: 62-466); central ...
11
Psychometric properties of the somatic complaints scale in Spanish children and adults
... The aim of this study was to validate the SLC (Rieffe et al., 2006, 2007) in two different populations (children and adults) in the Valencian Community by taking into account the effect that somatic complaints ...
8
BG3-5-The nervous and endocrine systems
... Nervous System Central Nervous System (CNS) Peripheral Nervous System (PNS) Somatic Nervous System Autonomic Nervous System Sympathetic System Parasympathetic System... The Periphe[r] ...
42
MDR3 mutations associated with intrahepatic and gallbladder cholesterol cholelithiasis: an update
... Multidrug resistance protein 3, as an ABC transport- er, participates to hepatic transport and secretion of phospholipid (phosphatidylcholine) and at this ac- count, may be at origin of common biliary cholesterol ...
7
Leucoencefalopata megalenceflica con quistes subcorticales (enfermedad de Van der Knaap)
... imaging shows edema, diffuse compromise of the white matter and frontotemporal subcortical cysts. Here is the first case reported in Peru; it is a girl with clinical findings and typical findings disclosed in the nuclear ...
6
Unstable mutations, new challenges for genetic counseling of inherited disorders [Spanish]
... Abstract: Unstable mutations, new challenges for genetic counseling of inherited disorders. Unstable mu- tations or amplification of DNA tandem repeats sequences constitute a new kind of genetic alteration ...
9
Marleny Chavarri, Ariadne Vegas García, Asia Y. Zambrano†, Zulay Gutiérrez y Jhonny R. Demey INSERCIÓN DEL GEN Agrobacterium rhizogenes ROLB EN MANGO (en inglés)
... The successful production of transgenic somatic em- bryos of Kent variety using A. rhizogenes mediated trans- formation is demonstrated. Twenty clones were produced per 0.5g of inoculated tis- sue with 80% of ...
5
Genotoxic profile of inhibitors of topoisomerases I (camptothecin) and II (etoposide) in a mitotic recombination and sex-chromosome loss somatic eye assay of Drosophila melanogaster
... tem allows the detection not only of homologous mitotic recombination, but also of illegitimate somatic recom- bination and sex-chromosome loss; these end points are also cancer-prone mechanisms [17]. Thus, using ...
8
Descargar este archivo PDF
... sativus L.): somatic embryogenesis and shoot regeneration. Scanning electron microscopic study on the in vitro organogenesis of saffron stigma and style-like structures. M[r] ...
8
Pharm4e Chapter 13
... • Nonnarcotic analgesic used for mild-to- moderate pain, inflammation, and fever • Two types of pain. – Somatic: dull, throbbing pain from skin, muscle, or bone[r] ...
128
B cell and Neutrophils
... We have shown here that neutrophils colonized splenic peri-MZ areas through a non- inflammatory pathway that became more prominent after post-natal mucosal colonization by bacteria. Splenic neutrophils expressed a ...
27
Presentation Unit 4
... The Nervous System Sensory nerves Motor nerves Autonomic nervous system Somatic nervous system Central nervous system Peripheral nervous system Sympathetic nervous system Parasym[r] ...
43