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Stem cells - Therapeutic use.

Mesenchymal stem cell therapy in retinal and optic nerve diseases: An update of clinical trials

Mesenchymal stem cell therapy in retinal and optic nerve diseases: An update of clinical trials

... mesenchymal stem cells (MSCs) have been obtained by several preclinical studies of various neurodegenerative ...the use of cell therapy in patients with neurodegenerative pathologies of optic nerve ...

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Genetic and molecular analysis or Sanfilippo C syndrome. Generation of a neuronal model using human induced pluripotent stem (iPS) cells and therapeutic strategies

Genetic and molecular analysis or Sanfilippo C syndrome. Generation of a neuronal model using human induced pluripotent stem (iPS) cells and therapeutic strategies

... mice liver has been shown to be toxic at high viral doses but safe at low doses, suggesting the viability of this treatment when low amounts of U1 snRNA viral particles are injected [20]. In the case of the c.1542 + ...

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Therapeutic Effect of Human Adipose Tissue-Derived Mesenchymal Stem Cells in Experimental Corneal Failure Due to Limbal Stem Cell Niche Damage

Therapeutic Effect of Human Adipose Tissue-Derived Mesenchymal Stem Cells in Experimental Corneal Failure Due to Limbal Stem Cell Niche Damage

... Limbal stem cells are responsible for the continuous renewal of the corneal ...these stem cells or their niche induces limbal stem cell deficiency (LSCD) leading to visual loss, chronic ...

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Adipose derived mesenchymal stem cells : are they a good therapeutic strategy for osteoarthritis? / Elena Damiá, Deborah Chicharro, Sergio López, Belén Cuervo, Mónica Rubio, Joaquín Sopena, José Manuel Vilar and José María Carrillo

Adipose derived mesenchymal stem cells : are they a good therapeutic strategy for osteoarthritis? / Elena Damiá, Deborah Chicharro, Sergio López, Belén Cuervo, Mónica Rubio, Joaquín Sopena, José Manuel Vilar and José María Carrillo

... the use of regenerative therapies, it has been reported that one option to restore degenerated cartilage are adipose-derived mesenchymal stem cells ...osteoarthritis, stem cells, and ...

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The future of stem cells in liver diseases

The future of stem cells in liver diseases

... «oval cells» in rodents (or «hepatic progenitor cells» in human), is activated when the replicative capacity of the main epithelial cell compartment is inhibited or exhaust- ...round cells express ...

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TítuloHedgehog signalling as a target in cancer stem cells

TítuloHedgehog signalling as a target in cancer stem cells

... of stem cells and their differentiation toward mature cells through pro-genitor or transient-amplifying ...of stem cells of the central nervous system and gut epithelium ...

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Bioethical implications of research on embryonic stem-cells

Bioethical implications of research on embryonic stem-cells

... Embryonic stem-cells are capable of differentiation in diverse cellular types and be used, in the future, for treating degenerative pathologies and ...embryonic stem cells and was based on a ...

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Nichos hematopoyéticos en médula osea

Nichos hematopoyéticos en médula osea

... Haematopoietic stem cells (HSCs) bound to the bone-marrow niche are mobilized in response to granulocyte colony-stimulating factor (G-CSF) or cyclophosphamide, or after peripheral myeloablation following ...

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Cancer genes hypermethylated in human embryonic stem cells.

Cancer genes hypermethylated in human embryonic stem cells.

... Within our four categories of genes we found those of Class A to be more enriched in Polycomb and bivalent marks than Class B genes, which suggests that the previously described scenario involving bivalent chromatin ...

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Comportamiento de clulas mesenquimales obtenidas de tejidos dentales: Revisin de literatura

Comportamiento de clulas mesenquimales obtenidas de tejidos dentales: Revisin de literatura

... the cells found ...by cells, can increase the proliferation and differentiation of PDLSC ...dental-follicle cells can stimulate the behavior of periodontal- ligament fibroblasts (46), and that ...

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Las patentes de células madre embrionarias humanas: ¿Amigas o enemigas de las barreras morales?

Las patentes de células madre embrionarias humanas: ¿Amigas o enemigas de las barreras morales?

... to stem cells have been patented, such as processes for isolation of stem cells from embryos or tissues, pro- cesses for genetically modifying stem cells for particular ...

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Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy

Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy

... pyknotic cells (yellow) and microglia (red) in the irradiated brain, compared to non-irradiated ...(resting cells) in the non-irradiated brain and bushy microglia (activated cells) in the irradiated ...

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TítuloGenerating Rho 0 cells using mesenchymal stem cell lines

TítuloGenerating Rho 0 cells using mesenchymal stem cell lines

... Rho-0 cells. Cells were cultured in standard medium (control) and in adipogenic medium for 9 ...days. Cells were fixed and double-stained with LD540 (red) for lipid droplets and Hoechst 33258 (blue) ...

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TítuloProteomic applications in the study of human mesenchymal stem cells

TítuloProteomic applications in the study of human mesenchymal stem cells

... the therapeutic effects of MSC microvesicles includes: surface receptors; signaling molecules (CDC42 and VAV2; cell adhesion); and MSC-associated antigens (CD109, CD151, CD248 and ...

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Clulas madre mesenquimales de mdula sea y de cordn umbilical en el tratamiento de enfermedades cardiovasculares

Clulas madre mesenquimales de mdula sea y de cordn umbilical en el tratamiento de enfermedades cardiovasculares

... their use was exclusive for their clinical application, restricted to the treatment of hematological diseas- es 11 ...marrow cells repre- sented a great potential in the therapy of other ex- tramedullary ...

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TítuloEffect of aging on behaviour of mesenchymal stem cells

TítuloEffect of aging on behaviour of mesenchymal stem cells

... In vivo senescence of MSCs is associated with bone-related disease because the cells lost the osteogenic capacity. In the last year, the number of studies based on gene therapy has increased with a view to ...

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Bioenergetics mechanism and autophagy in breast cancer stem cells

Bioenergetics mechanism and autophagy in breast cancer stem cells

... mammalian cells, when mitochondrial division is retarded by the expression of dominant-negative DRP1 or by RNAi of mitochondrial division proteins, tubular mitochondria become progressively more interconnected to ...

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Qu son las clulas troncales o clulas madre?

Qu son las clulas troncales o clulas madre?

... of stem cells in various tissues of the adult body and the human embryo’s capacity to generate stem cells have raised great interest among scientists, mainly because of the possible ...

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TítuloProstate carcinoma and stem cells

TítuloProstate carcinoma and stem cells

... Hedgehog signalling pathway regulates cell proliferation, tissue polarity and cell differentiation during nor- mal development. The Hedgehog family of growth factors activates a highly conserved signalling system for ...

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Efecto de autoinjerto contra tumor

Efecto de autoinjerto contra tumor

... 5. Porrata LF, Gertz MA, Geyer SM, Litzow MR, Gastineau DA, Moore SB, Pineda AA, Bundy KL, Padley DJ, Persky D, Lacy MQ, Dispenzieri A, Snow DS, Markovic SN. The dose of infused lymphocytes in the autograft directly ...

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