... in Tcellactivation and proliferation. Ag- dependent Tcellactivation is a cell-cell contact-dependent pro- cess, suggesting that mediators of intercellular ...
... of T lymphocytes by pokeweed mitogen (PWM ) is strictly monocyte ( Mo)-dependent and results in T-cell mitogenesis and interleukin-2 ( IL-2) secretion, coupled with an inability to utilize IL-2 due ...
... human T-cellactivation when stimulated with hMPV- inoculated monocyte-derived DCs pulsed with a super- antigen 9 ...of T-cellactivation, 24,45 here we used an antigenic peptide ...
... in Tcellactivation during an inflammatory immune ...early Tcellactivation as RARα-deficient T cells proliferate less efficiently than their wild-type counterparts upon ...
... + T cells that pro- mote virus clearance either directly by destroying infected cells or indirectly by limiting inflammation in the lungs ...display T-cellactivation levels that are sufficient ...
... the activation process, there are strong counter-regulating mechanisms for Tcellactivation, which are provided by inhibitory signaling ...the T-cell-expressed molecule ...
... and Tcellactivation following CD3 subunit of the TCR complex and was found to be TCR ...PKC activation, resulted in impairment of F-actin translocation, suggesting that autophosphorylation ...
... of T cells, making use of the Tcell receptors (TCRs) on their surface, to recognize a given agonist peptide–MHC ligand complex (pMHC) with high sensitivity ...between T cells and the agonist ...
... during Tcell priming. This crosstalk contributed to Tcellactivation, intracellular Ca 2+ responses, and cytokine ...NK cellactivation by DCs and NK ...
... diminished cell death, reveal that this population is more resistant to apopto- sis compared to the Foxp3 − CD4 thymocytes, but not enough to prevent the tTreg loss in abso- lute ...vival, cell number, ...
... To record the torque of each participant, a computerised load cell (Real Pow- er, Globus Italia) was positioned between two chains. One chain was placed on the arm of the machine that guided the gesture on which ...
... The difference in cytokine responses between control and peach- allergic subjects does not seem to be based on different genetic backgrounds, because TCLs from both groups displayed a s[r] ...
... Figure 1. tPA and EGF elicit a common transcriptional response in PANC-1 pancreas cancer cells. A. PANC-1 cells were serum-starved for 96 h and treated with increasing concentration of the recombinant active tPA for 6 h. ...
... Although we did not observe parasites in epicardial adipose tissue (EAT), our results demonstrate that inflammation and apoptosis of EAT is an important characteristic of T. cruzi infection in the guinea pig ...
... þ T helper (Th) cells play a central role in regulating the adaptive immune response associated with pathogen ...Th cell subsets have been ...regulatory T cells were characterized more recently 5–7 . ...
... cells. T-cell growth, optimal induction of IL-2- dependent effector molecules, such as perforin and granzyme B, and terminal differentiation of CD8 + Teff cells all depend on high IL-2R signaling (54, 92, ...
... signalling. Tcell receptor (TCR) signal transduction is initiated by the recognition of cognate peptide–MHC ...tyrosine-based activation motifs (ITAMs) of the CD3 γ chain, CD3 δ chain, CD3 ε chains ...
... diagnosed of FL in a single institution over a long period of time, confirms that HT is a common event in the natural history of FL. In the present series, the estimated risk of transformation was of 15% and 22% at 10 ...
... Alrededor de 10 a 30 años después de la infección, cerca del 30 al 40% de los pacientes desarrollan la fase crónica sintomática con manifestaciones cardíacas o digestivas (Rassi et al., 2010). La forma cardíaca es la más ...