T-cell activation
Functional Gap Junctions Accumulate at the Immunological Synapse and Contribute to T Cell Activation
... in T cell activation and proliferation. Ag- dependent T cell activation is a cell-cell contact-dependent pro- cess, suggesting that mediators of intercellular ...
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Desialylation of T lymphocytes overcomes the monocyte dependency of pokeweed mitogen induced T cell activation
... of T lymphocytes by pokeweed mitogen (PWM ) is strictly monocyte ( Mo)-dependent and results in T-cell mitogenesis and interleukin-2 ( IL-2) secretion, coupled with an inability to utilize IL-2 due ...
9
Human metapneumovirus keeps dendritic cells from priming antigen specific naive T cells
... human T-cell activation when stimulated with hMPV- inoculated monocyte-derived DCs pulsed with a super- antigen 9 ...of T-cell activation, 24,45 here we used an antigenic peptide ...
12
Retinoic acid as a modulator of T cell immunity
... in T cell activation during an inflammatory immune ...early T cell activation as RARα-deficient T cells proliferate less efficiently than their wild-type counterparts upon ...
15
Respiratory syncytial virus infection and immunity
... + T cells that pro- mote virus clearance either directly by destroying infected cells or indirectly by limiting inflammation in the lungs ...display T-cell activation levels that are sufficient ...
15
Contribution of dendritic cell/T cell interactions to triggering and maintaining autoimmunity
... the activation process, there are strong counter-regulating mechanisms for T cell activation, which are provided by inhibitory signaling ...the T-cell-expressed molecule ...
10
Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation
... and T cell activation following CD3 subunit of the TCR complex and was found to be TCR ...PKC activation, resulted in impairment of F-actin translocation, suggesting that autophosphorylation ...
13
Receptor pre-clustering and T cell responses: insights into molecular mechanisms
... of T cells, making use of the T cell receptors (TCRs) on their surface, to recognize a given agonist peptide–MHC ligand complex (pMHC) with high sensitivity ...between T cells and the agonist ...
11
Observaciones sobre el congreso La patognesis del VIH, virus contra hospedero, Alberta, Canad, marzo 9 14, 2014
... CD4+ T cells ...global T cell activation or cytokine release in a primary cell model of latent HIV infection ...without cell activation ...
5
Gap junction intercellular communications regulate NK cell activation and modulate NK cytotoxic capacity
... during T cell priming. This crosstalk contributed to T cell activation, intracellular Ca 2+ responses, and cytokine ...NK cell activation by DCs and NK ...
8
Trypanosoma cruzi Experimental Infection Impacts on the Thymic Regulatory T Cell Compartment
... diminished cell death, reveal that this population is more resistant to apopto- sis compared to the Foxp3 − CD4 thymocytes, but not enough to prevent the tTreg loss in abso- lute ...vival, cell number, ...
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Functional and structural of the erector spinae muscle during iso-metric lumbar extension
... To record the torque of each participant, a computerised load cell (Real Pow- er, Globus Italia) was positioned between two chains. One chain was placed on the arm of the machine that guided the gesture on which ...
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T-cell epitopes of the major peach allergen, Pru p 3: Identification and differential T-cell response of peach-allergic and non-allergic subjects
... The difference in cytokine responses between control and peach- allergic subjects does not seem to be based on different genetic backgrounds, because TCLs from both groups displayed a s[r] ...
7
Función y mecanismo de acción de los activadores del plasminógeno en cáncer
... Figure 1. tPA and EGF elicit a common transcriptional response in PANC-1 pancreas cancer cells. A. PANC-1 cells were serum-starved for 96 h and treated with increasing concentration of the recombinant active tPA for 6 h. ...
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Cell death and serum markers of collagen metabolism during cardiac remodeling in Cavia porcellus experimentally infected with Trypanosoma cruzi.
... Although we did not observe parasites in epicardial adipose tissue (EAT), our results demonstrate that inflammation and apoptosis of EAT is an important characteristic of T. cruzi infection in the guinea pig ...
10
NADþ protects against EAE by regulating CD4þ T cell differentiation
... þ T helper (Th) cells play a central role in regulating the adaptive immune response associated with pathogen ...Th cell subsets have been ...regulatory T cells were characterized more recently 5–7 . ...
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T CELL TOLERANCE AND MULTIFUNTIONAL ROLE OF il-2R
... cells. T-cell growth, optimal induction of IL-2- dependent effector molecules, such as perforin and granzyme B, and terminal differentiation of CD8 + Teff cells all depend on high IL-2R signaling (54, 92, ...
22
T CELL RECEPTOR SIGNALLING NETWORKS BRANCHED DIVERSIFIED AND BOUDEND
... signalling. T cell receptor (TCR) signal transduction is initiated by the recognition of cognate peptide–MHC ...tyrosine-based activation motifs (ITAMs) of the CD3 γ chain, CD3 δ chain, CD3 ε chains ...
13
Estudi del fenomen de la transformació histològica en síndromes limfoproliferatives indolents
... diagnosed of FL in a single institution over a long period of time, confirms that HT is a common event in the natural history of FL. In the present series, the estimated risk of transformation was of 15% and 22% at 10 ...
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Linfocitos t stem cell memory cd8+ y otras subpoblaciones de memoria en pacientes con enfermedad de chagas
... Alrededor de 10 a 30 años después de la infección, cerca del 30 al 40% de los pacientes desarrollan la fase crónica sintomática con manifestaciones cardíacas o digestivas (Rassi et al., 2010). La forma cardíaca es la más ...
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