... activate T cell mediated anti-tumor ...regulating T-cell cytotoxicity has achieved impressive clinical responses, as has adoptive cell transfer (ACT) using expanded tumor infiltrating lymphocytes (TIL) or ...
... and Tcells were evalu- ated at day 5 ...by Tcells specific for OVA- or flagellin-derived peptides could only be measured in mice challenged with ⌬ SPI-2, ⌬ SpiA, or ⌬ SpiC mutant Sal- ...
... Statins have been shown to modulate the number and the suppressive function of CD4 + FOXP3 + Tcells (Treg) in inlammatory conditions. However, it is not well established whether statin could also afect ...
... of Tcells against cancer cells. However it is known that T lymphocytes have osteoclastogenic activity in rheumatoid arthritis, which could increase the development of bone metastases, and ...
... and T-cell acute lymphoblastic leukemia cells, in the later through a mammalian target of rapamycin–dependent reg- ulation of cell-cycle ...Malignant Tcells produce and express VEGF ...
... results in protein tyrosine phosphorylation that includes phos- phorylation of ZAP-70, Vav, and PLC- ␥ 1. Total protein ty- rosine phosphorylation and phosphorylation of ZAP-70, Vav, and PLC- ␥ 1 were normal in 3BP2 ⫺/⫺ ...
... The study of mechanisms involved in resistance to HIV-1 infection or to AIDS progression is important to clarify viral pathogenesis to facilitate the development of new immunological therapies. Here, we evaluated the ...
... + Tcells in response to soluble antigens, both OVA and the Ag85B antigen from Mycobacterium tuberculosis ...to Tcells when DCs were loaded either with antigens as large particles or small ...
... and Tcells can increase osteoclast formation and bone ...of Tcells on the formation of osteoclasts in vivo and in ...of Tcells on osteoclasts in vivo, Balb/C mice were ...
... Background. T-cell populations regulate the balance of immune ...regulatory Tcells (Tregs) are crucial for maintaining negative control of various immune ...different T-cell subpopulations ...
... in cells as distinct as smooth muscle, rheumatoid synovial, endothelial and Tcells (Arencibia et ...re-stimulated Tcells (van den Brink et ...Jurkat Tcells that Gal-8S ...
... specifically, T-cell ...superantigen-induced T-cell activation by infect- ing conventional dendritic cells ...+ Tcells (OT-II), which not only display reduced pro- liferation, but also ...
... of T regulatory (Treg) and natural killer T (NKT) I cells, two cell populations of the innate immune response with opposing effects on the tumors, in a rat B cell lymphoma ...of T regulatory ...
... In this work, in addition to THs involvement in CYP3A4 expression and activation, we also demonstrate a THs role in response to chemotherapeutic drugs. Both Doxo and VCR are metabolized by enzymes of the CYP3A family, ...
... to T Con cells and positive signals to T Reg ...on T Con cells, but on T Reg cells it can interact with B and T lymphocyte attenuator (BTLA) or CD160 to deliver ...
... CD4+ T lymphocytopenia with clinical immunodeficiency and opportunistic infections in per- sons without immunodeficiency history and no other cause of ...CD4+ T lymphocytopenia with treatment of chronic ...
... CD4 T-cell-mediated immunity as a balance between distinct lineages of Th1 and Th2 cells has changed ...IL-17-producing Tcells uncovered a new subset of Th cells designated Th17 ...
... 31. Lopez M, Clarkson MR, Albin M, Sayegh MH, Najafian N. A novel mechanism of action for anti-thymocyte globulin: induction of CD4 CD25 Foxp3 regulatory Tcells. J Am Soc Nephrol 2006;17:2844-53. 32. ...
... of T-cells specific for minimally-cross- reactive epitopes did not cross-recognize the Phl p 1 derived epitopes in the corresponding ...of Tcells, capable of cross-recognizing these epitopes ...
... CD41 Tcells can be subdivided from a functional point of view into two main subsets: effector cells, which provide protection against exogenous offending agents, and regula- tory T (Treg) ...