Tumor Necrosis Factor
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TRAF1/C5 but not PTPRC variants are potential predictors of rheumatoid arthritis response to anti-tumor necrosis factor therapy.
... Rheumatoid arthritis (RA) is an inflammatory, chronic, and disabling disease. Methotrexate is the most widely used disease modifying antirheumatic drug (DMARD) in RA treatment. However, for refractory and severe cases, ...
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Antibody profiles in patients treated with tumor necrosis factor-alpha antagonists: new findings
... anti-tumor necrosis factor-alpha (anti–TNF- ␣ ) biologic agents has been associated with a reduction in the levels of specific autoantibodies, such as rheumatoid factor (RF) and anticyclic ...
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Eicosanoids and tumor necrosis factor alpha in the kidney
... nuclear factor of activated T cells (NFAT) 5-dependent; NFAT5 is also known as tonicity-responsive enchancer/osmotic- response element-binding protein (TonEBP/OREBP), a transcription factor crucial for ...
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Tumor Necrosis Factor α Regulates Glucocorticoid Synthesis in the Adrenal Glands of Trypanosoma cruzi Acutely Infected Mice The Role of TNF R1
... Adrenal gland nuclear fractions were obtained by homogeni- zation of frozen tissues in lysis buffer (PBS, 1% Triton X-100, 0.5% sodium deoxycholate, 0.1% SDS, 1 mM phenylmethylsul- fonyl fluoride and 10 g/ml leupeptin). ...
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Comparison of drug survival rates for tumor necrosis factor antagonists in rheumatoid arthritis.
... The multivariate regression model showed that the predic- tors of drug survival in anti-TNF therapy for RA were: being rhematoid-factor negative; being 60 years of age or older; and not having had previous ...
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Adherence to the Mediterranean Diet and Inflammatory Markers
... leptin, tumor necrosis factor alpha (TNF- α ), plasminogen activator inhibitor 1 (PAI-1) and high-sensitivity C-reactive protein (hs-CRP) in adults, but not in young ...
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Obesidad e inflamación
... 16. Nophar Y, Kemper O, Brakebusch C, Engelmann H, Zwang R, Adreka D, et al. Soluble forms of tumor necrosis factors (TNF- Rs). The cDNA for the type 1 TNF-R, cloned using amino acid sequence data of its ...
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New evidence for the therapeutic potential of curcumin to treat nonalcoholic fatty liver disease in humans
... To evaluate the production of intracellular interferon-gamma (IFN-γ) by T cells, PBMCs were incubated in the presence or absence of 10 nM leptin for 19 hr at 37°C and re-stimulated for 4 hr at 37°C with 25 ng/mL phorbol ...
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Aspectos ms relevantes del sndrome peridico asociado al receptor del factor de necrosis tumoral
... Hereditary autoinflammatory disorders are a range of heterogeneous conditions that have as a common feature the appearance of unprovoked inflammatory attacks, which may be systemic or occur in localized niches of the ...
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![Pleiotrophin regulates microglia mediated neuroinflammation / R Fernández Calle [et al ]](https://data02.123doks.com/thumbv2/123dok_es/000/578/578801/cover.webp)
Pleiotrophin regulates microglia mediated neuroinflammation / R Fernández Calle [et al ]
... of tumor necrosis factor-α (TNF-α), interleukin 1β (IL-1β), interleukin 6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), interleukin 4 (IL-4), and interleukin 10 (IL-10) were measured by X-Map ...
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Vol. 89, Núm. 3 (2018)
... Several processes are involved in the association between obesity and inflammation, including adi- pocyte hypertrophy and hyperplasia, macrophage recruitment, increased hypoxia, increased oxidative stress, and increased ...
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Tumor intrabdominal desmoplásico de células pequeñas redondas. Reporte de un caso
... cell tumor is a rare mesenchymal ...the tumor located in the parietal peritoneum was made, which was guided by laparoscopy, where a dermoplastic small round cell intra-abdominal tumor is ...extensive ...
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Expresin del receptor del factor de necrosis tumoral en monocitos infectados por citomegalovirus humano
... Introducción. El citomegalovirus humano (HCMV) es el miem- bro más representativo de los herpesvirus beta, causa infecciones persistentes y latentes con periodos frecuentes de reactivación. Afecta a todos aquellos que se ...
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Alemtuzumab for the treatment of steroid-refractory acute graft-versus-host disease.
... Treatment with alemtuzumab was well tolerated, with only 5 patients developing headache, low-grade fever, and/or chills after the first dose. None of the pa- tients developed injection-site skin reactions. Transient ...
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Factor de necrosis tumoral: actividad biolgica en neumopatas intersticiales
... la necrosis tisular a dosis que en ratones de tipo silvestre (es decir, sin la deficiencia del receptor) induce necrosis, sin embargo al incrementar significativamente la concentración plasmática de la ...
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El factor de necrosis tumoral alfa (FNT α) en la patogenesis de la artritis reumatoide y el riesgo de tuberculosis con infliximab (un agente ANTI FNT α)
... Tumor necrosis factor alpha (TNF-α) is a key regulator of inflammation and a crucial agent in granuloma formation. As such, the abnormal regulation of TNF-α function plays a major role in the ...
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DAS-28-based EULAR response and HAQ improvement in rheumatoid arthritis patients switching between TNF antagonists
... 23. Solau-Gervais E, Laxenaire N, Cortet B, Dubucquoi S, Duquesnoy B, Flipo RM: Lack of efficacy of a third tumour necrosis factor alpha antagonist after failure of a soluble receptor and a monoclonal ...
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Expresión de genes inmunorrelacionados y de estrés térmico en abulón rojo, Haliotis rufescens, sintomático al síndrome de deshidrataciónExpression of immune related genes and heat shock in red abalone Haliotis rufescens asymptomatic to the withering syndrome
... Like Factor; AbTNF-α, Abalone Tumor Necrosis-alfa; MEP, Macrófagos Expressed Protein), antioxidant metabolism (Catalase; SeGPx, Selenium dependent glutathione-S- transferase; GSTisof1, ...
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Estudio de las características metabólicas, hormonales e inmunoinflamatorias de mujeres con síndrome de ovarios poliquísticos con o sin obesidad Análisis del impacto del tratamiento con atorvastatina
... Los pacientes que tienen carcinomas tiroideos de células C pueden tener concentraciones altas en ausencia de infecciones (Tateno, 2010). También se detectan concentraciones elevadas de procalcitonina en el primer día de ...
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Estudi de la funció supressora de la cèl·lules iNKT en el control de la resposta autoimmunitària a la Diabetis Tipus 1 humana
... diversos factor solubles (ex: citocines i/o factors de creixement), a partir de partícules individuals marcades amb fluorocroms, els quals la longitud d’ona d’emissió es llegida entre 660-680 ...un factor ...
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