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tumor suppressor gene

Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells

Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells

... Another relevant regulatory genetic network is medi- ated by p53. Several microRNAs have been reported to be involved in the p53 pathway, either being regulated by p53 or acting directly to suppress the expression of p53 ...

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Silencing of tumor suppressor genes RASSF1A, SLIT2, and WIF1 by promoter hypermethylation in hereditary breast cancer

Silencing of tumor suppressor genes RASSF1A, SLIT2, and WIF1 by promoter hypermethylation in hereditary breast cancer

... affect tumor suppressor genes and proto-oncogenes occur during cancer development and ...in gene expression, so the detection of these events helps us to under- stand tumor ...of tumor ...

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New insights into the role of the immune microenvironment in breast carcinoma.

New insights into the role of the immune microenvironment in breast carcinoma.

... in tumor cells correlates with better relapse free and overall ...a tumor suppressor gene that acts as a transcriptional repressor of some breast cancer oncogenes ...

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Tumor dentinognico de clulas fantasma  Un tumor odontognico raro

Tumor dentinognico de clulas fantasma Un tumor odontognico raro

... El tumor dentinogénico de células fantasma es una neoplasia rara, es la contraparte del quiste odontogénico calcificado. Es localmente invasi- vo, caracterizado por islas de células epiteliales sin núcleo ...

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Tumor phyllodes

Tumor phyllodes

... En la biopsia por aspiración con aguja fina, los tumores benignos se caracterizan por la mezcla de células estromales y epiteliales, además de celularidad moderada y pleomórfico ausente. El tumor phyllo- des ...

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Tumor del seno endodrmico: presentacin de un caso

Tumor del seno endodrmico: presentacin de un caso

... Los tumores derivados de las células germinales constituyen el 15­20 % de todos los tumores ováricos en el adulto y el 60­70 % en los niños. 1 Son el segundo grupo de tumores más frecuentes, después de los epiteliales. ...

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Tumor del estroma gastrointestinal (GIST) como tumor anexial

Tumor del estroma gastrointestinal (GIST) como tumor anexial

... identificando tumor dependiente de íleon de 30 x 35 cm, lobulado, vascularizado con lóbulo iz- quierdo abscedado, con adherencias a asas intestinales, pared, epiplón, ovario y fimbria derecha, ovario izquierdo ...

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Tumor de Krukenberg

Tumor de Krukenberg

... El tumor de Krukenberg (TK) fue descrito por primera vez en 1896 por Friederich Krukenberg en su tesis para culminar los estudios de Medicina, basado en el estudio de 6 casos de tumores ováricos atípicos de la ...

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Tumor de Klatskin

Tumor de Klatskin

... El colangiocarcinoma es un tumor maligno originado en el epitelio de los conductos biliares intra o extrahepáticos y fue descrito por primera vez por Durand-Fardel en 1840. Es poco frecuente y representa menos del ...

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Osteocondroma del radio  Presentacin de un caso

Osteocondroma del radio Presentacin de un caso

... We present a patient with an osteochondroma located in the metaphysis of the left radius, diagnosed by radiographic and anatomopathological studies, at the Celia Sánchez Manduley University Hospital of Manzanillo, Granma ...

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Tumor glmico

Tumor glmico

... La lesión es difícil de observar; el diagnóstico se hace en relación con la historia clínica y las pruebas clínicas positivas. Se ha descrito que la historia es de dolor intenso sin causa clínica evidente durante un ...

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Tumor de Pancoast

Tumor de Pancoast

... y lateral), que en la mayoría de los casos evidencia la presencia de una opacidad homogénea en el ápex pulmonar, con aspecto de masa (45-72%), o cambios sutiles como un engrosamiento apical unilateral (28-55%), ...

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Tumor de Askin

Tumor de Askin

... Askin’s tumor is a rare neoplasm of the chest wall that belongs to the group of primitive neuroectodermal tumors (PNETs), which are derivatives from neuroectodermal plu- ripotent neural crest ...

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Molecular Biology In Young Women With Breast Cancer: From Tumor Gene Expression To DNA Mutations

Molecular Biology In Young Women With Breast Cancer: From Tumor Gene Expression To DNA Mutations

... differential tumor gene expression, increased genetic susceptibility, and specific genomic signatures, compared to older women with ...on tumor biology and genomic signatures in ...

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Tumores testiculares en el perro

Tumores testiculares en el perro

... La mayoría de los autores coinciden en señalar que es el tumor testicular más frecuente en perros (Planellas et al., 2007; Fogel, 2009; Martí, 2011). Los TCS provocan la deformación testicular al aparecer ...

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Aspectos ms relevantes del sndrome peridico asociado al receptor del factor de necrosis tumoral

Aspectos ms relevantes del sndrome peridico asociado al receptor del factor de necrosis tumoral

... Hereditary autoinflammatory disorders are a range of heterogeneous conditions that have as a common feature the appearance of unprovoked inflammatory attacks, which may be systemic or occur in localized niches of the ...

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The function of MicroRNA in hepatitis B virus related liver diseases: from Dim to Bright

The function of MicroRNA in hepatitis B virus related liver diseases: from Dim to Bright

... protein increased the expression of DNMT3A (DNA methyltransferase 3A, a target of miR-101) by down- regulating miR-101 and enhanced DNA methylation of tumor-suppressor genes. In addition, investiga- tors ...

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miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer

miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer

... The significantly lower miR-23b expression in biopsies of cervical cancer than in LSILs and HSILs, may be the result of gradual miR-23b promoter methylation and al- terations of other gene expression regulatory ...

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Role of gene methylation in antitumor immune response: Implication for tumor progression

Role of gene methylation in antitumor immune response: Implication for tumor progression

... of the basic DNA methylation profile during early development might be mediated through histone modification. Histones are currently known to be subjected to nine different types of posttranslational modifications, ...

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The Reprimo Gene Family: A Novel Gene Lineage in Gastric Cancer with Tumor Suppressive Properties

The Reprimo Gene Family: A Novel Gene Lineage in Gastric Cancer with Tumor Suppressive Properties

... RPRM gene family was differentially retained, as not all RPRM genes are present in all main vertebrate groups (Figure ...RPRM gene was not retained in birds [1], searches in the most recent version of bird ...

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