Type 1 diabetes

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Genetic manipulation of the pancreas: cell and gene therapy approaches for type 1 diabetes

Genetic manipulation of the pancreas: cell and gene therapy approaches for type 1 diabetes

... Type 1 diabetes is characterized by progressive destruction of pancreatic -cells, resulting in insulin deficiency and hyperglycemia. Insulin replacement therapy allows diabetic patients to lead ...

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HLA risk haplotype: insulin deficiency in pediatric Type 1 diabetes

HLA risk haplotype: insulin deficiency in pediatric Type 1 diabetes

... to analyze data. Results: We included 46 patients, 72 siblings, and 160 controls. Prevalence of anti-tyrosine phosphatase-re- lated islet antigen 2 and anti-glutamic acid decarboxylase antibodies was higher in patients ...

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Research Program on Type 1 Diabetes and Youth Depression in Puerto Rico

Research Program on Type 1 Diabetes and Youth Depression in Puerto Rico

... of Diabetes and Digestive and Kidney Diseases [NIDDK] and particular psychological studies about youth Diabetes and DEP, conducted at the University of Puerto Rico (UPR), Río Piedras Campus, and discuss its ...

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Simulation & control in type 1 diabetes

Simulation & control in type 1 diabetes

... Tomas Willis notices the sweet taste of the urine of people with diabetes. Frederick Banting, Charles Best, John Macleod and James Collip contribute in the discovery of insulin. Eli Lilly and Company begins ...

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Plasma myeloperoxidase measurement in children and adolescents with Type 1 Diabetes

Plasma myeloperoxidase measurement in children and adolescents with Type 1 Diabetes

... Myeloperoxidase (MPO), a main component of the leukocytes azurophilic granules, presents an increased activity when a leucocyte activation occurs, contributing to innate immunity. MPO is associated with oxidative stress ...

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Glycogenic hepatopathy associated with type 1 diabetes mellitus as a cause of recurrent liver damage

Glycogenic hepatopathy associated with type 1 diabetes mellitus as a cause of recurrent liver damage

... from type 1 diabe- tes, celiac disease, and autoimmune thyroiditis, several potential causes of damage could be hypothesized, including celiac hepatitis, fatty liver, and autoimmune ...controlled ...

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Glucose-Insulin regulator for type 1 diabetes using high order neural networks

Glucose-Insulin regulator for type 1 diabetes using high order neural networks

... Abstract—In this paper a Glucose-Insulin regulator for Type 1 Diabetes using artificial neural networks (ANN) is proposed. This is done using a discrete recurrent high order neural network in order ...

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Albuminuria and Glomerular Filtration Rate in Individuals with Type 1 Diabetes Mellitus: Contribution of Metabolic Syndrome

Albuminuria and Glomerular Filtration Rate in Individuals with Type 1 Diabetes Mellitus: Contribution of Metabolic Syndrome

... with type 1 diabetes mellitus as the disease progresses over ...with type 1 diabetes ...with type 1 diabetes mellitus who were diagnosed over 10 years ago ...

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IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).

IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).

... Methods and Results: Here we perform a replication and fine mapping of the IL2RA gene region analyzing 3 SNPs previously associated with multiple sclerosis (MS) and 5 SNPs associated with type 1 ...

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Artificial pancreas using a personalized rule-based controller achieves overnight normoglycemia in patients with type 1 diabetes

Artificial pancreas using a personalized rule-based controller achieves overnight normoglycemia in patients with type 1 diabetes

... Objective: This study assessed the efficacy of a closed-loop (CL) system consisting of a predictive rule-based algorithm (pRBA) on achieving nocturnal and postprandial normoglycemia in patients with type 1 ...

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Linear closed-loop control using Luenberger observer applied to insulin administration for type 1 diabetes

Linear closed-loop control using Luenberger observer applied to insulin administration for type 1 diabetes

... follows: 1) as the simulation iterates at 1 second and the pump infusion a bolus each 5 minutes, the control signal uc(t) is accumulated during this 5 minutes; 2) as insulin pumps cannot infusion any exact ...

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Automatic regulatory control in type 1 diabetes without carbohydrate counting

Automatic regulatory control in type 1 diabetes without carbohydrate counting

... A schematic of the closed-loop system with the Automatic Regulation of Glucose (ARG) algorithm is presented in Fig. 1. As shown in that figure, the ARG algorithm is also composed of a Safety Auxiliary Feedback ...

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Characterization of cannabinoid-induced relief of neuropathic pain in rat models of type 1 and type 2 diabetes

Characterization of cannabinoid-induced relief of neuropathic pain in rat models of type 1 and type 2 diabetes

... of diabetes mellitus: the streptozotocin-induced model of type 1 diabetes and the Zucker Diabetic Fatty rat model of type 2 ...STZ-induced diabetes, in which both cannabinoid ...

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Niveles séricos de la proteína quimioatrayente de monocitos 1 y su relación con los polimorfismos -2518 a/g y -927 g/c en su gen en niños con obesidad

Niveles séricos de la proteína quimioatrayente de monocitos 1 y su relación con los polimorfismos -2518 a/g y -927 g/c en su gen en niños con obesidad

... Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that regulates migration and infiltration of monocytes, macrophages, memory T cells, basophils and natural killer (NK) cells to the site of ...

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Detección de pacientes con diabetes tipo 2 no diagnosticada con factores de riesgo en farmacias comunitarias de Portugal

Detección de pacientes con diabetes tipo 2 no diagnosticada con factores de riesgo en farmacias comunitarias de Portugal

... detección tanto de casos sospechosos como de casos diagnosticados, se puede explicar porque los estudios mencionados no incluían exclusiva- mente pacientes mayores de 45 años y hacían una selección a partir de un escore ...

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Data mining for the diagnosis of type 2 diabetes

Data mining for the diagnosis of type 2 diabetes

... [1]. Diabetes increases the risks of developing kidney disease, blindness, nerve damage, blood vessel damage and it contributes to heart ...with diabetes, and estimated that the number of cases of ...

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Dental iron precipitates in patients with Type 2 diabetes

Dental iron precipitates in patients with Type 2 diabetes

... extracted for reasons that merit extraction from 40 individuals with and without DM to analyze dentin tissue. Horizontal and longitudinal slices of tooth samples were made and later stained with 10% potassium ...

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Análisis de la relación entre microbiota intestinal, permeabilidad intestinal y niveles de glucemia, en niños con Diabetes Mellitus tipo 1 comparados con niños con diabetes tipo MODY 2 y controles sanos

Análisis de la relación entre microbiota intestinal, permeabilidad intestinal y niveles de glucemia, en niños con Diabetes Mellitus tipo 1 comparados con niños con diabetes tipo MODY 2 y controles sanos

... estudio Diabetes Autoimmunity Study in the Young (DAISY) fueron consistentes con los hallazgos del estudio BABYDIAB en que la presencia de autoinmunidad pancreática en la sangre del cordón, no era predictora del ...

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Diabetes mellitus y sus complicaciones  La epidemiologia, las manifestaciones clnicas de la  diabetes tipo 1 y 2  Diabetes Gestacional  Parte 1

Diabetes mellitus y sus complicaciones La epidemiologia, las manifestaciones clnicas de la diabetes tipo 1 y 2 Diabetes Gestacional Parte 1

... En el otro extremo del círculo vicioso encontramos el impacto de la diabetes en la sociedad y las familias. En el 2007, se estima que el mundo gastará entre 215 y 375 mil millones de dólares (USD) para hacer ...

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Adopcin de conductas saludables en una cohorte prospectiva de hijos de un grupo de pacientes diabticos tipo 2

Adopcin de conductas saludables en una cohorte prospectiva de hijos de un grupo de pacientes diabticos tipo 2

... American Diabetes Association and National Institute of Diabetes, Digestive and Kidney ...of type 2 diabetes (Position Statement). Diabetes Care 2002; 25: ...S. Diabetes mellitus ...

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