Unfolded protein response
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The Two Faces of Janus: Unfolded Protein Response Autophagy in Cell Death and Survival
... the unfolded protein response which has pro-death and pro-survival arms (Verfaillie et ...the unfolded protein response in the three glioma cell lines we studied (1321N1, SF767 ...
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Identification of Novel Components of the Unfolded Protein Response in Arabidopsis
... Recently, a heterotrimeric NF-Y complex was identified as a nuclear interacting partner of bZIP28 (Liu and Howell, 2010). The resulting transcriptional complex then consists of ER stress-specific homo- or heterodimers of ...
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Activation of the unfolded protein response enhances motor recovery after spinal cord injury
... the unfolded protein response (UPR), a process that propagates through the spinal ...X-box-binding protein 1 (XBP1) or activating transcription factor 4 (ATF4) expression, two major UPR ...
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Identification of Novel Components of the Unfolded Protein Response in Arabidopsis
... Recently, a heterotrimeric NF-Y complex was identified as a nuclear interacting partner of bZIP28 (Liu and Howell, 2010). The resulting transcriptional complex then consists of ER stress-specific homo- or heterodimers of ...
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BAX inhibitor 1 regulates autophagy by controlling the IRE1 alpha branch of the unfolded protein response
... located protein containing six transmembrane regions with anti-apoptotic functions, involved in the suppression of in- trinsic cell death mediated by ER calcium release (Xu and Reed, 1998; Xu et al, 2008), ER ...
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Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
... binding protein 1 (XBP1) in the nervous system, a key regulator of the unfolded protein response (UPR), protects dopaminergic neurons against a PD-inducing ...of protein homeostasis in ...
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Endoplasmic reticulum stress independent activation of unfolded protein response kinases by a small molecule ATP mimic
... the proposed roles of both the IRE1 and PERK branches, providing cytoprotective and pro-apoptotic outputs, respectively (Lin et al., 2007). Moreover, AD60, as a DFG-out kinase inhibitor, reversed the effects of IPA on ...
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The physiological role of the unfolded protein response in plants
... in protein bodies of floury-2 maize also increases when UPR is activated (Shank et ...zein protein accumulation l5 days after pollination (DAP) and Shank et ...
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CDNF induces the adaptive unfolded protein response and attenuates endoplasmic reticulum stress induced cell death
... BiP protein levels in HEK293-T cells treated with 1 μM TG at 24 h ...and protein levels showed that TG induced a progressive increase in BiP that reach 4-fold incre- ment at 12 h of exposure compared to ...
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La respuesta a proteínas mal plegadas como blanco terapéutico en la Enfermedad de Alzheimer
... in protein homeostasis, that is regulated for the most part by endoplasmic reticulum ...the Unfolded Protein Response (UPR) which alleviates the protein aggregation and ER ...
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inmunoproteasoma
... link protein misfolding and proteostasis regulation with inflammation in auto- inflammatory diseases are still ...the unfolded protein response (UPR, the clas- sical ER stress ...
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Hormonal regulation during initial berry development in grapevine
... families related to gibberellin biosynthesis (Serrani et al., 2008). Also, transgenic tomato lines silenced for Indole Acetic Acid 9 (IAA9), a gene that encodes an Aux/IAA protein, presented parthenocarpic fruits. ...
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Imbalances in protein metabolism in critical care patient with systemic inflammatory response syndrome at admission in intensive care unit.
... Tables II and III show general characteristics and biochemical profile in critical ill patients at admission in ICU stay. Taking into account biochemical parame- ters, critical care patients showed in general disturban- ...
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Genes implicados en el desarrollo de la semilla de Arabidopsis thaliana (L.): caracterización de los genes AtAnkTm
... Four genes involved in different aspects of development (8%) were selected. Two of them are involved in cell wall synthesis or modification (At5g59170, encoding a cell wall protein precursor, extensin; and ...
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TítuloHydrogen sulfide and inflammatory joint diseases
... Rheumatoid arthritis (RA) and osteoarthritis (OA) represent two of the most common arthritides in the developed world. RA, a chronic inflammatory autoimmune disease affecting diarthrodial joints, is characterized by ...
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Aproximacions genètiques per l’estudi de les funcions de la proteïna fosfatasa Ptc1 en S. cerevisiae
... El segon mecanisme de regulació per fosforilació de Cdc28 té lloc al residu conservat Tyr19, el qual es troba molt pròxim al lloc d’unió a ATP. Al llevat S. cerevisiae aquesta regulació depèn de les activitats oposades ...
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Methylglyoxal and methylglyoxal modified collagen as inducers of cellular injury in gingival connective tissue cells
... approach represented an acute stimu- lus on cells that probably occurs dur- ing sudden rises in glycaemia (soluble MGO). The second experiment proba- bly corresponds to a chronic effect derived from the long-lasting ...
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Report on the fourth TDR/IDRI meeting on second generation vaccine against Leishmaniasis Merida, Yucatan, Mexico, May 1 3, 2001
... M. Barral-Neto (Universidade Federal de Bahia, Bahia, Brazil) described a priming in-vitro (PIV) system that was used to evaluate the immune response of naïve individuals following in-vivo vaccination with ...
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Función del microARN miR396 y los Factores de Transcripción GRFs en el desarrollo de Arabidopsis thaliana
... Pentatricopeptide repeat PPR superfamily protein ACX6,acyl-CoA oxidase 6 FAD-binding Berberine family protein hydroxyproline-rich glycoprotein family protein Pathogenesis-related thaumat[r] ...
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Importancia inmunolgica de la protena N en la infeccin por virus de la rabia
... tection response; within it, the immune system makes an effort to stop the pathogen ...immune response, that are broadly distributed in the zoological scale, from crustaceous and insects to human ...
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