β-catenin
Wnt/β catenin signaling stimulates the expression and synaptic clustering of the autism associated Neuroligin 3 gene
... endogenous β-catenin binds to novel TBE consensus sequences in the Nlgn3 ...Wnt/ β -catenin signaling to the transcription of the Nlgn3 gene and support a functional role for the signaling ...
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Pigmented hepatocellular adenoma with β catenin activation: case report and literature review
... with β -catenin ...with β -catenin nuclear expression and inflammatory fea- tures and to review the cases of pigmented HCAs in the ...of β-catenin and a partial hepatic resection ...
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Are Changes in the Wnt/β Catenin Pathway Involved in Cocaine and Stress Induced Long Term Neuroadaptations?
... of β-catenin in the PFC after a cocaine challenge on day 28, we found no changes when compared to controls regardless of the behavioral ...measured β-catenin in the PFC after a period of ...
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Preoperative chemoradiotherapy in rectal cancer induces changes in the expression of nuclear β-catenin: prognostic significance.
... In accordance with other series, our results show that metastatic recurrence is the main pattern of recurrence for our patients and isolated locoregional recurrence occurs rarely after TME plus RT [1]. Nowadays, the ...
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Wnt/β catenin signaling pathway in hepatocellular carcinomas cases from Colombia
... of β-catenin activation is quite dif- ficult; indeed, it is necessary to take in account the heterogeneous mechanisms of β-catenin activation in HCC, the interaction with other signaling ...
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TRPM4 regulates Akt/GSK3 β activity and enhances β catenin signaling and cell proliferation in prostate cancer cells
... TRPM4, a calcium-activated monovalent-selective cation channel (Guinamard et al., 2010; Launay et al., 2002), has been found to be overexpressed in a variety of human tumors, including prostate cancer (Berg et al., 2016; ...
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Cytokeratin19 positive hepatocellular carcinoma is associated with increased peritumoral ductular reaction
... For IHC, after a phosphate-buffered saline wash, sections were transferred into 10 mM sodium citrate buffer (pH 6.0), and antigen unmasking was performed in a micro- wave. After cooling down, sections were incubated in ...
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WASP 1, a canonical Wnt signaling potentiator, rescues hippocampal synaptic impairments induced by A beta oligomers
... induced β -catenin stabilization, suggesting that β -catenin is not involved in the effects of WASP-1 on ...require β -catenin-mediated gene transcription, has been previously ...
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Emerging roles of Wnts in the adult nervous system
... a β -catenin-responsive reporter gene in HEK293T/ STF recombinant cells, suggesting that reduced signalling through the canonical Wnt pathway may predispose people to ...3 β (GSK3 β ) was also ...
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Signaling pathway cross talk in Alzheimer's disease
... A β toxicity Numerous studies have shown that Wnt signaling compo- nents are altered in AD: (a) among the Wnt components that are affected in AD, it was shown that β-catenin levels are reduced in AD ...
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HOTAIR Knockdown Decreased the Activity Wnt/ß-Catenin Signaling Pathway and Increased the mRNA Levels of Its Negative Regulators in Hela Cells
... In this work, we analyzed the participation of HOTAIR in TET1 expression, Wnt/β- catenin pathway and expression, methylation and hidroxymethylation of some negative regulators of this pathway in HeLa cells. ...
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Wnt signaling in the regulation of adult hippocampal neurogenesis
... In rodents, evidence indicate that a decline in Wnt signal- ing is associated to the age-dependent reduction in neurogene- sis. During aging, the levels of Wnt-3 protein in hippocampal astrocytes and also the number of ...
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Wnt/beta catenin pathway in the prefrontal cortex is required for cocaine induced neuroadaptations
... Wnt/ β -catenin, the planar cell polarity and the Wnt/calcium pathways (Ciani & Salinas ...GSK3 β (glycogen syn- thase kinase 3 β ) leading to β -catenin stabilization and ...
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Contribution of genetic and epigenetic mechanisms to Wnt pathway activity in prevalent skeletal disorders
... nuclear β -catenin levels in primary osteoblasts from patients with 116 hip fractures and hip osteoarthritis, determined β -catenin gene 117 expression, and explored if the differences in Wnt ...
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Efecto de HOTAIR sobre TET1 y la vía WNT en la línea celular HeLa.
... and β-catenin nuclear ...Wnt/β- catenin pathway) were evaluated by ...Wnt/ β-catenin negative regulators through a decrease in their promoter’s methylation ...
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Actividad de una nueva combinación de β lactámico e inhibidor de β lactamasas (imipenem/relebactam)
... ➢ Resistencia adquirida: es la capacidad que tienen las bacterias para ganar resistencia a antibióticos a través de mutaciones de genes cromosómicos o mediante la adquisición de genes de resistencia a través de ...
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La resistencia microbiana en el contexto actual y la importancia del conocimiento y aplicacin en la poltica antimicrobiana
... fármacos β-lactámicos, aunque las bacterias productoras de NDM-1 pueden retener la susceptibilidad al ...combinaciones β- lactámico e inhibidor β-lactamasa, ceftazidima- avibactam y ...
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Caracterización del papel del TGF-Beta en el neuroblastoma metastásico óseoTGF-Beta role in neuroblastoma bone metastasis
... Neuroblastoma (NB) is the most common extracranial solid tumor among pediatric cancers. A unique feature of NB is the high metastatic rate, and bone is one of the main sites of metastatic occurrence. Patients with NB ...
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DIABETES FARM 212 2009
... Debido a que los GLUT son bidireccionales en la membrana celular y a que las células β del páncreas tienen un exceso de GLUT, la concentración de glucosa dentro de la célula β esta e[r] ...
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Pérdida de peso, dieta vs ejercicio pdf
... cerebro se adapta a la utilización de cuerpos cetónicos (además de glucosa), sobre todo.. β -D-hidroxibutirato, un subproducto de la β -oxidación hepática de los ácidos grasos.[r] ...
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