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vascular smooth muscle

Store operated interactions between plasmalemmal STIM1 and TRPC1 proteins stimulate PLCβ1 to induce TRPC1 channel activation in vascular smooth muscle cells

Store operated interactions between plasmalemmal STIM1 and TRPC1 proteins stimulate PLCβ1 to induce TRPC1 channel activation in vascular smooth muscle cells

... In vascular smooth muscle cells (VSMCs), stimulation of canonical transient receptor potential channel 1 (TRPC1) protein-based store-operated channels (SOCs) mediates Ca 2+ entry pathways that ...

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Evidence that Orai1 does not contribute to store operated TRPC1 channels in vascular smooth muscle cells

Evidence that Orai1 does not contribute to store operated TRPC1 channels in vascular smooth muscle cells

... Ca 2C -permeable store-operated channels (SOCs) mediate Ca 2C entry pathways which are involved in many cellular functions such as contraction, growth, and proliferation. Prototypical SOCs are formed of Orai1 proteins ...

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Functional vascular smooth muscle-like cells derived from adult mouse uterine mesothelial cells.

Functional vascular smooth muscle-like cells derived from adult mouse uterine mesothelial cells.

... organs, vascular smooth muscle cells (VSMCs) originate from an epithelial-to-mesenchymal transition (EMT) of embryonic mesothelial cells ...acquire smooth muscle (SM) markers upon ...

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TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential dependent coupling with PTEN

TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential dependent coupling with PTEN

... ABSTRACT: Vascular smooth muscle cells (VSMCs) play critical roles in the stability and tonic regulation of vascular ...of vascular disorders such as atherosclerosis and restenosis ...

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Tungstate-Targeting of BKαβ1 Channels Tunes ERK Phosphorylation and Cell Proliferation in Human Vascular Smooth Muscle

Tungstate-Targeting of BKαβ1 Channels Tunes ERK Phosphorylation and Cell Proliferation in Human Vascular Smooth Muscle

... Sodium tungstate, Pertussis Toxin (PTX), GDPβS, Noradrenaline (NA) and EGF were from Sigma-Aldrich. Iberiotoxin (IbTX) was from Alomone Labs Ltd. (Jerusalem, Israel). Tissue cul- ture media and supplements were from ...

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Angiotensin II Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy

Angiotensin II Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy

... of vascular smooth muscle cells ...aortic smooth muscle cells with Ang II 100 nM and measured autophagic markers at 24 h by Western ...

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Remodeling of vascular smoth muscle ion channels involved in purinergic signaling in essential hypertension

Remodeling of vascular smoth muscle ion channels involved in purinergic signaling in essential hypertension

... Increased vascular tone in essential hypertension involves a sustained rise in total peripheral ...into vascular smooth muscle cells (VSMCs), contraction and ...to vascular tone is ...

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Utero placental expression of angiotensin (1 7) and ACE2 in the pregnant guinea pig

Utero placental expression of angiotensin (1 7) and ACE2 in the pregnant guinea pig

... arteries display intense immunoreactivity for Ang-(1–7) and ACE2, a moderate signal for kallikrein, a faint signal in scant cells for B2R, VEGF and KDR and absence of eNOS (Figure 3). This localization of the ...

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El 17 estradiol modula los efectos de los cambios de la contractilidad vascular producidos por la insulina

El 17 estradiol modula los efectos de los cambios de la contractilidad vascular producidos por la insulina

... on vascular smooth muscle cells and on vascular endothelium have been extensively studied, they are still not completely understood and probably many interacting mechanisms may be involved in ...

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FPdeFA

FPdeFA

... and vascular smooth muscle in coronary sinus and AV valves that, under normal circumstances, manifest synchronous electrical activity but develop delayed afterdepolarizations and triggered activity ...

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Arterioesclerosis

Arterioesclerosis

... 62. Omenn GS, Beresford SAA, Motulsky AG. Preventing coronary heart disease: B vitamins and homocysteine. Circulation 1998;97:421-4. 63. Chobanian AV, Dzau VJ. Renin angiotensin system and atherosclerotic vascular ...

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Mecanismos de contracción relajación vascular y celular: papel central de la guanilato ciclasa soluble y de

Mecanismos de contracción relajación vascular y celular: papel central de la guanilato ciclasa soluble y de

... Rat vascular smooth muscle cells were either treated or not with sodium nitroprusside (SNP, 10 mmol/L) for 24 h and incubated either in the presence of TR (50 mmol/L, grey bars) or vehicle (V, white ...

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Implementation of the technique in isolated organ vascular as tool for the validation of medicinal plants: Study of the vasodilator effect of the S  scutellarioides

Implementation of the technique in isolated organ vascular as tool for the validation of medicinal plants: Study of the vasodilator effect of the S scutellarioides

... Effect of time in the contraction of vascular smooth muscle and EC 50 for phenylephrine. The maximum tension for phenylephrine at the third and fifth hours did not show statistically significant ...

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Cell size, cell cycle, and alpha-smooth muscle actin expression by primary human lung fibroblasts

Cell size, cell cycle, and alpha-smooth muscle actin expression by primary human lung fibroblasts

... Fig. 7. In situ end labeling (ISEL) of fragmented DNA and immuno- fluorescence detection of a -smooth muscle actin ( a -SMA) in primary human lung fibroblasts. Shown are phase-contrast (A, C, and E) and ...

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Functional Role of Connexins and Pannexins in the Interaction Between Vascular and Nervous System

Functional Role of Connexins and Pannexins in the Interaction Between Vascular and Nervous System

... of smooth muscle cells evoked a Panx-1 channel-dependent ATP release, and then, the authors proposed that a 1-adrenoceptor stimulation is coupled to P2Y receptor activation via ATP release through Panx-1 ...

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Efecto de diferentes factores de crecimiento recombinantes sobre un modelo "in vitro" de cicatrización del estroma corneal humano

Efecto de diferentes factores de crecimiento recombinantes sobre un modelo "in vitro" de cicatrización del estroma corneal humano

... α-SMA (αSMA, ACTA2): actina alfa de músculo liso, α smooth muscle actin. αSMA+ : células actina alfa de músculo liso positivas. APC : células presentadoras de antígenos, antigen prese[r] ...

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Angiogenic, hyperpermeability and vasodilator network in utero placental units along pregnancy in the guinea pig (Cavia porcellus)

Angiogenic, hyperpermeability and vasodilator network in utero placental units along pregnancy in the guinea pig (Cavia porcellus)

... of smooth muscle cells and no trophoblasts were observed in their periphery or within the muscle ...the muscle layer, and presented a positive signal for VEGF, Flt-1, KDR, B2R and ...

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Pre- and post-junctional bradykinin B2 receptors regulate smooth muscle tension to the pig intravesical ureter.?

Pre- and post-junctional bradykinin B2 receptors regulate smooth muscle tension to the pig intravesical ureter.?

... The ureterovesical junction plays an important role in both the active transport of urine bolus from ureter to bladder and the prevention of vesicoureteral reflux during bladder filling. 14 The study of peptide receptors ...

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Tumores estromales gastrointestinales :

Tumores estromales gastrointestinales :

... Los resultados de dichos estudios apoyan la hipótesis formulada por Kindblom y col. (88), que los GISTs se originarían de una célula madre, que se diferenciaría hacia un fenotipo de células marcapasos o CIC. Es por este ...

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32 2 MUSCULAR SYSTEM ppt

32 2 MUSCULAR SYSTEM ppt

... Skeletal muscle cells are large, have many nuclei, and vary in ...skeletal muscle, which is about 1 millimeter long is found in the middle ...skeletal muscle, which may be as long as 30 centimeters, ...

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