... Ca 2C -permeable store-operated channels (SOCs) mediate Ca 2C entry pathways which are involved in many cellular functions such as contraction, growth, and proliferation. Prototypical SOCs are formed of Orai1 proteins ...
... ABSTRACT: Vascularsmoothmuscle cells (VSMCs) play critical roles in the stability and tonic regulation of vascular ...of vascular disorders such as atherosclerosis and restenosis ...
... Sodium tungstate, Pertussis Toxin (PTX), GDPβS, Noradrenaline (NA) and EGF were from Sigma-Aldrich. Iberiotoxin (IbTX) was from Alomone Labs Ltd. (Jerusalem, Israel). Tissue cul- ture media and supplements were from ...
... Increased vascular tone in essential hypertension involves a sustained rise in total peripheral ...into vascularsmoothmuscle cells (VSMCs), contraction and ...to vascular tone is ...
... arteries display intense immunoreactivity for Ang-(1–7) and ACE2, a moderate signal for kallikrein, a faint signal in scant cells for B2R, VEGF and KDR and absence of eNOS (Figure 3). This localization of the ...
... on vascularsmoothmuscle cells and on vascular endothelium have been extensively studied, they are still not completely understood and probably many interacting mechanisms may be involved in ...
... and vascularsmoothmuscle in coronary sinus and AV valves that, under normal circumstances, manifest synchronous electrical activity but develop delayed afterdepolarizations and triggered activity ...
... Rat vascularsmoothmuscle cells were either treated or not with sodium nitroprusside (SNP, 10 mmol/L) for 24 h and incubated either in the presence of TR (50 mmol/L, grey bars) or vehicle (V, white ...
... Effect of time in the contraction of vascularsmoothmuscle and EC 50 for phenylephrine. The maximum tension for phenylephrine at the third and fifth hours did not show statistically significant ...
... Fig. 7. In situ end labeling (ISEL) of fragmented DNA and immuno- fluorescence detection of a -smoothmuscle actin ( a -SMA) in primary human lung fibroblasts. Shown are phase-contrast (A, C, and E) and ...
... of smoothmuscle cells evoked a Panx-1 channel-dependent ATP release, and then, the authors proposed that a 1-adrenoceptor stimulation is coupled to P2Y receptor activation via ATP release through Panx-1 ...
... of smoothmuscle cells and no trophoblasts were observed in their periphery or within the muscle ...the muscle layer, and presented a positive signal for VEGF, Flt-1, KDR, B2R and ...
... The ureterovesical junction plays an important role in both the active transport of urine bolus from ureter to bladder and the prevention of vesicoureteral reflux during bladder filling. 14 The study of peptide receptors ...
... Los resultados de dichos estudios apoyan la hipótesis formulada por Kindblom y col. (88), que los GISTs se originarían de una célula madre, que se diferenciaría hacia un fenotipo de células marcapasos o CIC. Es por este ...
... Skeletal muscle cells are large, have many nuclei, and vary in ...skeletal muscle, which is about 1 millimeter long is found in the middle ...skeletal muscle, which may be as long as 30 centimeters, ...