[PDF] Top 20 Adipose and muscle tissue metabolism in cancer cachexia

... acids and glycerol, followed by further degradation, into acetyl units [30]. In our study, only patients in the CC group had significantly increased in vivo lipolysis although there was no ... See full document

... White adipose tissue (WAT) is a key energy depot in humans and most ...participates in energy metabolism mainly through its secretion of cytokines and ...or tissue ... See full document

... (fat in contact with the rectus abdominis muscle), this finding led us to speculate a possible functional link between healthy adipose tissue expansion and muscle mitochondrial ... See full document

... regulation and function. To elucidate the relationship between serum irisin and FNDC5 mRNA expression levels, we evaluated plasma irisin levels and FNDC5 gene expression in the hypothalamus, ... See full document

... , and it has been proposed to mediate the ben- eficial effects of exercise on metabolism, inducing the browning of sc adipocytes and thermogenesis by increas- ing uncoupling protein 1 (UCP1) levels ... See full document

... monophosphates and regulate cellular nucleoside and nucleotide levels (Bianchi and Spychala, ...studied in vitro using a semi-purified enzymes extracted from rat and guinea pig skeletal ... See full document

... expression and serum concentrations of adipocytokines (leptin and adi- ...FASN and serum concentrations of ...dependent in obesity while leptin increases, adiponectin ...present in ... See full document

... expression in the sc adipose depot, an inverse rela- tionship to insulin resistance, and a GIP-resistant pheno- type in obese-derived ...VAT and meta- bolic complications such as T2D, ... See full document

... implicated in promotion of EMT in vitro ...step in PGE 2 synthesis, upstream of PGE synthases ...COX-1 and the inducible isoform COX-2, which is up-regulated in CRC and is a ... See full document

... clustered in chromosome 9q in humans and chromosome 4 in ...IFNβ, and single IFNε and an IFNω (Hertzog et ...bacterial and parasite infections (Schneider et ...death ... See full document

... microRNAs and HIF-1; such aspects include angiogenesis, apoptosis, cell cycle regulation, metabolism, metastasis, proliferation and anticancer therapy resistance ( Crosby et ...that in a ... See full document

... maintained in a temperature-controlled environment (23°C) with a fixed 12-hour light/dark cycle and fed a standard laboratory rat diet (Ganave, Argentina) for one week (stabilization period); the ... See full document

... "bibliomic" and genomic data known as Recon 1 was made available ten years ago (Duarte et ...biology and post-genomic analyses along with different types of mathematical models was proposed as an ... See full document

... EAT in patients receiving peritoneal dialysis or hemodialysis than that in controls, and an increased EAT volume in the presence of the malnutrition, inflammation, and arteriosclerosis ... See full document

... ESCs in future cell therapy ...donor and recipient is the same ...face in this case concerns the limited differ- entiation potential presented by these ... See full document

... interest in the last few years because of their potential role in regeneration and tissue re- pair ...experimental and/or clinical use in acute myocar- dial infarction, skin ... See full document

... The plasma pharmacokinetics, tissue distribution, excretion, and metabolism of gambogenic acid (GNA), potential antitumor candidate, were investigated in rats. GNA showed linear pharmaco[r] ... See full document

... expressed in adipose tissues, is a potent target for anti-obesity and anti-diabetic drug ...intake, and promoting body fat loss, lipid oxidation, oxygen consumption and mitochondrial ... See full document

... mouse and human adipose tissue contained a greater quantity of mitochondria and produce more ROS (Fig ...function in adipocytes is essential for their biology, and ... See full document

... lipid metabolism, such as peroxi- some proliferator-activated receptor-gamma (PPAR-γ) and sterol regulatory element-binding proteins-1c (SREBP-1c) ...posed in the promotion and maintenance of ... See full document