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Repressive effects of resveratrol on androgen receptor transcriptional activity.
... development of prostatic cancer as well as other cancers ...percent of all cancers could be prevented by attention to dietary factors ...lycopene, resveratrol (RSV), and other anti-androgen ...
The impact of point mutations in the human androgen receptor: classification of mutations on the basis of transcriptional activity.
... tration of DHT with D221H, P504L and D528G, while P340L manifested a striking dose-dependent ...transactivational activity [58]. Mutation of either of the PSTLSL motifs located between ...
Registered report: the androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man
... targets of AR in prostate tissue from patients with CRPC, ADT-responsive PC, or untreated PC, compared with benign prostate ...thousands of AR target genes. Of the 150 genes that were upregulated in ...
Effects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cells.
... up of an admixture of disparate cell types that are broadly segregated into an epithelial or a stromal compartment based upon their localization with regards to the basement ...how androgen action ...
Peripheral CLOCK regulates target-tissue glucocorticoid receptor transcriptional activity in a circadian fashion in man.
... one of the two major arms of this system, consists of the hypothalamic paraventricular nucleus (PVN), the pituitary corti- cotrophs and the adrenal glands, which, respectively, employ ...
Letter: The Effects of High Fat Diet and Resveratrol on Mitochondrial Activity of Brown Adipocytes ( 2016;31:328-35, Cheol Ryong Ku et al.)
... ber of brown adipocytes in both diet ...mitochondrial activity related to increased expression of UCP-1, phospho-adenosine monophosphate-activated protein kinase (phospho-AMPK), and estrogen ...
Androgen suppresses the proliferation of androgen receptor-positive castration-resistant prostate cancer cells via inhibition of Cdk2, CyclinA, and Skp2.
... majority of prostate cancer (PCa) patient receiving androgen ablation therapy eventually develop castration-resistant prostate cancer ...that androgen treatment suppresses Skp2 and c-Myc through ...
Response: The Effects of High Fat Diet and Resveratrol on Mitochondrial Activity of Brown Adipocytes ( 2016;31:328-35, Cheol Ryong Ku et al.)
... comments on the study. In our manuscript published in volume 31, issue 2 of Endo- crinology and Metabolism, we reported that resveratrol (RSV) can improve insulin resistance through a mechanism that ...
Omeprazole and lansoprazole enantiomers induce CYP3A4 in human hepatocytes and cell lines via glucocorticoid receptor and pregnane X receptor axis.
... induction of GR-dependent luciferase activity by synthetic glucocorticoid dexamethasone varied from 27-fold to 97-fold, as compared to vehicle-treated ...weak effects on basal activity ...
ZMIZ1 preferably enhances the transcriptional activity of androgen receptor with short polyglutamine tract.
... inactivation of AR function through impairing the androgen-dependent transcription ...lengths of polyQ repeats within the AR NTD can result in dysfunctional AR and have been identified in patients ...
Design principles for riboswitch function.
... stabilization of conformation A inadvertently drove the riboswitch into the kinetically-driven ...introduction of the aptamer sequence to the regulatory element decreased the regulatory activity ...
Modulation of androgen receptor signaling in hormonal therapy-resistant prostate cancer cell lines.
... GTPases of the Ras family (RHOB, RHOU), mitogen-activated protein kinase cascade (MAP2K4, MKNK2, TRIB1) and other protein kinases/phosphatases (PPM1A, PPP2CB, PIK3R3, ...effect on cellular proliferation ...
Wine polyphenol resveratrol inhibits contractions of isolated rat uterus by activation of smooth muscle inwardly rectifying potassium channels
... number of plant spe- cies including grapes. The beneit of resveratrol to health is widely re- ...ported. Resveratrol has been found to promote relaxation of non-pre- gnant and pregnant ...
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... variety of roles in lipid, protein and carbohydrate metabolism, biosynthesis, and signal transduction ...many of which have been shown to require Mn 2+ , instead of Fe 2+ , for survival ...
Thyrotoxic Periodic Paralysis and Polymorphisms of the , , and Genes in Men with Graves Disease
... type of ADRB2 in skeletal mus- cle, and thyroid hormone sensitizes cells to β-adrenergic stimu- lation of the sodium pump ...lation of adrenergic ...number of patients ...
Androgen receptor expression in triple-negative breast cancer
... Committee on Cancer) is based on all information available prior the first definitive treatment and includes the findings on pathological examination, imaging studies, operative findings on ...
Post-translational regulation of Oct4 transcriptional activity.
... depending on arrangements of the octamer motif, and presence of DNA motifs for additional transcription factors, Oct4 can form heterodimers with multiple partners or homodimers in one of ...
Performance Of Different Tillage Implements And Their Effects On Sorghum And Maize Grown In Gezira Vertisols Sudan
... the effects of six tillage methods on sorghum and maize establishment and yield, weeds control and some soil physical ...performance of chisel plow and disc harrow was also ...depth of ...
Effect of Physical Activity During Pregnancy on Birth Outcomes in Mothers Presenting at the Antenatal Clinic of De Soysa Maternity Hospital, Colombo 08
... level of physical activity a stranded questionnaire and a dairy card (PIN3 physical activity questionnaire) were ...data on labor ...age of 224 ...physical activity they ...
Inhibition of SIRT1 Transcription inResveratrol-differentiated Medulloblastoma Cells
... prognosis of MB is very ...degree of resection. As an important part of therapy, chemotherapy can reduce risk of recurrence, which is usually ...