[PDF] Top 20 Design and Synthesis of Pironetin Analogue/Colchicine Hybrids and Study of Their Cytotoxic Activity and Mechanisms of Interaction with Tubulin
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Design and Synthesis of Pironetin Analogue/Colchicine Hybrids and Study of Their Cytotoxic Activity and Mechanisms of Interaction with Tubulin
... containing colchicine fragments, see, for example: (a) Bombuwala, ...inhibitors colchicine and ...A. Synthesis and SAR requirements of adamantane− colchicine conjugates ... See full document
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Design and synthesis of pironetin analogue/combretastatin A 4 hybrids containing a 1,2,3 triazole ring and evaluation of their cytotoxic activity
... -tubulin and those that bind to b ...numerous and contains products which cause either disruption or stabilization of ...well-known colchicine [6] and the combretastatins [7] ... See full document
9
Design and Synthesis of Pironetin Analogue/Combretastatin A 4 Hybrids and Evaluation of Their Cytotoxic Activity
... on pironetin have been ...presence of the conjugated C2C3 double bond and of the hydroxyl group at C-9, either free or methylated, are essential for the biological ...presence of a (7 ... See full document
18
From white lab coats and crazy hair to actual scientists: exploring the impact of researcher interaction and performing arts on students' perceptions and motivation for science
... contact with scientists so that they can get to know the actual person who works in science and not the one represented in fiction has been suggested as a way to break negative stereotypes, particularly ... See full document
29
Chemical constituents and standardization of Piper piedecuestanum TREL & YUNCK With antiplasmodial and cytotoxic activity
... concentration of 3000 mg.L − 1 . The standards and extracts were dissolved in an acetonitrile-water solution (1:1) and filtered before the injection by Nylon membrane ...mg/mL of marker ... See full document
12
Early-age hepatocellular carcinoma associated with hepatitis B infection in South America
... cohort study aimed at identifying the demographics and risk factors associated with HCC in South ...to their respective institutional review ...review of patient characteristics at the ... See full document
9
Synthesis and conformational analysis of leptocarpin derivatives Influence of modification of the oxirane ringon leptocarpin's cytotoxic activity
... point of view, leptocarpin under acid conditions can produce two types of cyclation ...attack of the double bond ∆ 4,5 on C10 (6-Exo-Tet) producing the opening of the oxirane ring (Figure ... See full document
15
Isolation and identification of compounds present in rhizomes of Paris axialis H. Li and study of their cytotoxic effects
... 3 Institute of Chinese Materia Medica, China Academy of Chinese Medicinal Science,. Beijing 100700, P.R[r] ... See full document
1
Synthesis and cytotoxic activity of tri acyl ester derivatives of uridine in breast cancer cells
... results of cell viability obtained by MTT assay with uridine, tri-esterified derivatives and ...uridine and its derivatives, to the lower concentrations evaluated, did not present significant ... See full document
9
Green synthesis of polysaccharides based gold and silver nanoparticles and their promissory biological activity
... applications of Ps-based silver nanoparticles in nanomedicine, a hemolytic assay using blood agar plates was carried ...RSC1 and BSA1 extracts (see Figure ...presence of sodium citrate residues in ... See full document
9
Amidinate Aluminium Complexes as Catalysts for Carbon Dioxide Fixation into Cyclic Carbonates
... change of cocatalyst from tetrabutylam- monium bromide to tetrabutylammonium iodide has a positive effect for each of complexes 1–6, the conversion of styrene oxide 7a into styrene carbonate 8a was ... See full document
7
Desarrollo de dos nuevas sondas fluorogénicas derivadas de la bis-vainillina para la detección de catiónes metalicos trivalentes
... derivatives of bis-vainilline that contain semicarbazide or hydrazines can act as sensors of ...3- and 3’- with hydrazoline and isoniazide, using fluorescence as analytical signal for ... See full document
5
Cincuenta años con la piedra de la locura : apuntes autobiográficos de un científico argentino
... El primer trabajo que relaciona alteraciones mentales con patología pineal fue publicado en 1686 por Edmund King en los Philosophical Transactions of the Royal Society, Londres, 185, 228-231. En un enfermo de ... See full document
252
Non-Conventional Techniques for the Generation and modification of Graphenes: Applications to the Syntesis of electro-Active Scaffolds for On-Demand Drug Delivery
... performed with a TGA Q50 (TA Instruments) at 10 ºC/min in a nitrogen ...recorded with an Invia Renishaw microspectrometer equipped with a He–Ne ...immersing of silicon oxide surfaces (Si-Mat ... See full document
211
Mechanisms of Pituitary Tumorigenesis Study of Angiogenic and Proliferation factors
... expression of VEGF and FGF2, two potent angiogenic factors, and the existence of linear correlation between VEGF and ...indicative of the existence of angiogenesis in ... See full document
6
Student-teachers’ written reports about their own learning processes from lesson study
... lesson study model in Valencia (Spain) was developed and adapted based on the Norwegian lesson study model designed by Larssen and Drew ...student-teachers and taught to the same group ... See full document
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Steroid saponins and other constituents from the rhizome of Trillium tschonoskii Maxim and their cytotoxic activity
... 1702 ISSN 0326-2383 KEY WORDS: Cytotoxicity, GC-MS, Steroid saponin, Trillium tschonoskii Maxim.. *Author to whom correspondence should be addressed.[r] ... See full document
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3. SAPOGENINS FROM THE HUSK OF CHENOPODIUM QUINOA, THE OBTAINING OF THEIR DERIVATIVES, AND THE EVALUATION OF THEIR CYTOTOXIC ACTIVITY.
... Cytotoxic evaluation The cytotoxicity of the four isolated sapogenins was evaluated in one normal-like human breast epithelial cell line MCF-10A and in one breast cancer cell line JIMT-1[r] ... See full document
10
A comprehensive study of the synthesis, characterization and activity of TiO2 and mixed TiO2/SiO2 photocatalysts
... photocatalytic activity of the sample Degussa P25 to the enhancement in the magnitude of the space-charge potential, which is created by contact between the different phases present and by the ... See full document
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Antiplasmodial and Cytotoxic Activity of Piper Piedecuestanum Trel and Yunck
... Preparation of extracts and isolation of compounds: Piper piedecuestanum (PP) plant material was subjected to a desiccation process at room temperature with aeration and without ... See full document
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