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[PDF] Top 20 Determination of sulpiride in rabbit plasma by LC-ESI-MS and its application to a pharmacokinetic study

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Determination of sulpiride in rabbit plasma by LC-ESI-MS and its application to a pharmacokinetic study

Determination of sulpiride in rabbit plasma by LC-ESI-MS and its application to a pharmacokinetic study

... Detection involved positive ion mode electrospray ionization (ESI), and selective ion monitoring (SIM) mode was used for quantification of target fragment ions m/z 342.0 for sulpiride a[r] ... See full document

1

Gradient elution LC-ESI-MS determination of cilostazol in rat plasma and its application

Gradient elution LC-ESI-MS determination of cilostazol in rat plasma and its application

... Electrospray ionization (ESI) source was applied and operated in positive ion mode; selected ion monitoring (SIM) mode was used to quantification using target fragment ions m/z 370.0 fo[r] ... See full document

1

Determination of troxerutin in rabbit plasma by LC-ESI-MS and its application to a pharmacokinetic study

Determination of troxerutin in rabbit plasma by LC-ESI-MS and its application to a pharmacokinetic study

... Electrospray ionization (ESI) source was applied and operated in positive ion mode; selected ion monitoring (SIM) mode was used to quantification using target fragment ions m/z 765 for [r] ... See full document

1

Simultaneous quantification of 6,7-di-hydroxyligustilide and gastrodin in rat plasma by LC-MS: application to pharmacokinetic study of tianshu capsule

Simultaneous quantification of 6,7-di-hydroxyligustilide and gastrodin in rat plasma by LC-MS: application to pharmacokinetic study of tianshu capsule

... A LC-MS method was developed and validated for simultaneous determination of 6, 7-di-hy- droxyligustilide and gastrodin in rat plasma, and which was ... See full document

1

Determination of gemcitabine in rabbit plasma by LC-ESI-MS using an Allure PFP propyl column

Determination of gemcitabine in rabbit plasma by LC-ESI-MS using an Allure PFP propyl column

... Electrospray ionization (ESI) source was applied and operated in positive ion mode; selected ion monitoring (SIM) mode was used to quantify gemcitabine using target fragment ions m/z 264[r] ... See full document

1

Quantification of torsemide in rabbit plasma by liquid chromatography/electrospray mass spectrometry and its application

Quantification of torsemide in rabbit plasma by liquid chromatography/electrospray mass spectrometry and its application

... A sensitive and simple liquid chromatography/electrospray mass spectrometry (LC-ESI-MS) method for determination of torsemide in rabbit plasma using one-step protein precipitation was de[r] ... See full document

1

Determination of berberine and berberrubine in rabbit plasma by capillary electrophoresis with amperometric detection and its application to pharmacokinetic study

Determination of berberine and berberrubine in rabbit plasma by capillary electrophoresis with amperometric detection and its application to pharmacokinetic study

... A simple and selective method based on capillary electrophoresis with amperometric detec- tion has been developed for the separation and determination of berberine BB and berberrubine BB[r] ... See full document

1

Simultaneous determination of midazolam and 1’-hydroxymidazolam in rat plasma by protein precipitation and LC-MS: application to pharmacokinetic study

Simultaneous determination of midazolam and 1’-hydroxymidazolam in rat plasma by protein precipitation and LC-MS: application to pharmacokinetic study

... Calibration curves were linear in the concentration ranges of 5-2000 ng/mL for mida- zolam and 10-2000 ng/mL for 1’-hydroxymidazolam, with a lower limit of quantification (LLOQ) of 5 ng/[r] ... See full document

1

Determination of bupropion and hydroxybupropion by LC-MS/MS in rat and its application to assessment of CYP2B6 activity

Determination of bupropion and hydroxybupropion by LC-MS/MS in rat and its application to assessment of CYP2B6 activity

... veloped and validated for quantitation of bupropion (BUP) and its metabolite hydroxybupropion (HBUP) in rat plasma and urine using carbamazepine as an internal standard. Chromatographic [r] ... See full document

1

Determination of meropenem in rabbit plasma by LC-MS/MS

Determination of meropenem in rabbit plasma by LC-MS/MS

... Electrospray ionization (ESI) source was applied and operated in positive ion mode; multiple reaction monitoring (MRM) mode was used to quantification using target fragment ions m/z 384.[r] ... See full document

1

Determination of esomeprazole in rabbit plasma by liquid chromatography-mass spectrometry and its application to a pharmacokinetic study

Determination of esomeprazole in rabbit plasma by liquid chromatography-mass spectrometry and its application to a pharmacokinetic study

... Detection involved positive ion mode electrospray ion- ization (ESI), and selective ion monitoring (SIM) mode was used for quantification of target fragment ions m/z 198 for esomeprazol[r] ... See full document

1

Determination of bupropion hydrochloride in rat plasma by LC-MS/MS and Its application to pharmacokinetic study

Determination of bupropion hydrochloride in rat plasma by LC-MS/MS and Its application to pharmacokinetic study

... A selective and sensitive liquid chromatography-tandem mass spectrometry method was de- veloped and validated for quantitation of bupropion hydrochloride in rat plasma using triazolam as[r] ... See full document

1

Determination of diphenhydramine hydrochloride in rabbit plasma by LC-MS/MS and its application to a pharmacokinetic study

Determination of diphenhydramine hydrochloride in rabbit plasma by LC-MS/MS and its application to a pharmacokinetic study

... A sensitive and selective liquid chromatography tandem mass spectrometry (LC–MS/MS) method for determination of diphenhydramine hydrochloride in rabbit plasma was developed and validat- [r] ... See full document

1

Determination of dextromethorphan in rabbit plasma by LC-MS/MS and its application to pharmacokinetic study

Determination of dextromethorphan in rabbit plasma by LC-MS/MS and its application to pharmacokinetic study

... A highly sensitive liquid chromatographic tandem mass spectrometric (LC-MS/MS) method for determination of dextromethorphan in rabbit plasma using triazolam as the internal standard (IS)[r] ... See full document

1

Determination of tolbutamide in rabbit plasma by LC-MS/MS and its application to pharmacokinetic study

Determination of tolbutamide in rabbit plasma by LC-MS/MS and its application to pharmacokinetic study

... A sensitive and selective liquid chromatography–tandem mass spectrometry method (LC–MS/MS) for the determination of tolbutamide in rabbit plasma was developed and validated over the conc[r] ... See full document

1

Determination of pantoprazole in rat plasma by LC–MS/MS and its application to pharmacokinetics

Determination of pantoprazole in rat plasma by LC–MS/MS and its application to pharmacokinetics

... A highly sensitive liquid chromatographic mass spectrometric (LC-MS/MS) method for de- termination of pantoprazole in rat plasma using omeprazole as the internal standard (IS) was develo[r] ... See full document

1

Determination of meloxicam in human plasma administrated with four drugs by LC method: application to a pilot bioavailability study

Determination of meloxicam in human plasma administrated with four drugs by LC method: application to a pilot bioavailability study

... Chromatographic separation of meloxicam, piroxicam, other active ingredients, di- acerein metabolite (Rhein) and plasma interferents was achieved with a C18 column, using a mobile phase [r] ... See full document

1

Determination of erlotinib in rabbit plasma by liquid chromatography mass spectrometry

Determination of erlotinib in rabbit plasma by liquid chromatography mass spectrometry

... Electrospray ionization (ESI) source was applied and operated in posi- tive ion mode; multiple reaction monitoring (MRM) mode was used to quantification using target frag- ment ions m/z[r] ... See full document

1

Determination of free cyclosporine A with a LC-MS/MS method: Application to C2 monitoring in rabbits

Determination of free cyclosporine A with a LC-MS/MS method: Application to C2 monitoring in rabbits

... Following ultrafiltration for fCsA, chromatographic separation was per- formed on an Agilent Zorbax SB-C18 column (100 mm x 2.1 mm, 3.5 µm ) with acetonitrile and 0.1 % am- monium hydrox[r] ... See full document

1

Determination of dichlobenil and its major metabolite (BAM) in onions by PTV–GC–MS using PARAFAC2 and experimental design methodology

Determination of dichlobenil and its major metabolite (BAM) in onions by PTV–GC–MS using PARAFAC2 and experimental design methodology

... loadings of chromatographic, spectral and sample modes obtained for DIC (the loadings of the chromatographic mode in PARAFAC2 models are referred throughout the paper to loadings scaled ... See full document

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