[PDF] Top 20 Development and characterization of controlled release mucoadhesive tablets of captopril
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Development and characterization of controlled release mucoadhesive tablets of captopril
... Mucoadhesive tablets of Captopril were prepared by wet granulation technique using different concentrations of HPMC K4M, HPMC K15M, Xanthan gum and Guar ...85# and were ... See full document
8
Development and characterization of controlled release mucoadhesive tablets of captopril to increase the residence time in the gastrointestinal tract
... It was evident from the study that the for- mulation F10 containing HPMC K15M and xanthan gum (1:1) exhibited maximum bioadhesive strength of 31.59 ± 0.05 gm and in vitro drug release wa[r] ... See full document
1
Design, development and in vitro characterization of Pioglitazone loaded mucoadhesive buccal devices
... loaded mucoadhesive buccal patches were prepared by solvent casting ...weighed and measured quantities of Eudragit RS 100 (controlled release polymer) and Hydroxy propyl methyl ... See full document
7
Deamidation of pseudopeptidic molecular hydrogelators and its application to controlled release
... Study of the gelation capabilities of SucValHex and SucValOct was performed at room temperature by addition of water to a DMSO solution of the gelator (10% DMSO in the final ...(mgc) ... See full document
16
Preparation, characterization and in vitro evaluation of stable mucoadhesive intranasal microsphere of L-Dopa
... Treatment of in vitro data to mathematical model of different kinetic equations indicated that drug release from the microspheres was best characterized by the Korsmeyer-Peppas model. T[r] ... See full document
1
Evaluation of the effect of drug solubility behaviour on the rate of release from the hydrophilic matrix system
... To select the suitable concentration level of controlled release polymer for the formulation of predefined extended release formulation based on the solubility behaviour of active substa[r] ... See full document
1
Deamidation of pseudopeptidic molecular hydrogelators and its application to controlled release
... nals of free gelator that coexists with the fibrillar network (NMR- silent) at different temperatures ...solubility of both SucValHex (ca. 1 mM) and SucValOct ...rium of the gel network, being ... See full document
105
Study of drug release retardant capability of hydroxypropylmethylcellulose and carbopol in matrix tablets
... The present study was undertaken to investigate the effect of nature of polymers like HPMC, carbopol-934P and their content levels on the release profiles of water soluble drug, diclofen[r] ... See full document
1
Comprimidos mucoadherentes bicapa para la administración bucal de carvedilol: Estudios in vitro e in vivo
... system of carvedilol was designed for buccal application with the objective of improving bio- availability and producing sustained ...934P and hydroxypropylmethylcellulose K4M were employed as ... See full document
16
Hydrophilic and hydrophobic polymer Based naproxen buccal mucoadhesive film: design and in vitro evaluation
... The aim of the present study was to develop a sustained release mucoadhesive buccal film of naproxen, which can be used to treat the inflammation in the oral cavity.. The mucoadhesive bu[r] ... See full document
1
Development and evaluation of carvedilol/ polyethylene oxide matrix tablets
... The mechanism involved in drug release was characterized by anomalous behavior for all formulations in phosphate buffer whereas in acid conditions they presented a Fickian kinetics, Case[r] ... See full document
1
Formulation and evaluation of controlled release matrix tablet of diltiazem HCl by using HPMC and guar gum as polymeric matrix material
... preparation of controlled release tablets of Diltiazem, drug and polymer were weighed accurately, mixed thoroughly then other excipients were added and mixed by ...water ... See full document
6
Preparation and Characterization of Cerium (III) Doped Captopril Nanoparticles and Study of their Photoluminescence Properties
... process and have been studied. Captopril may be applied in the treatment of hypertension and some types of congestive heart failure and for preventing kidney failure due to high ... See full document
5
Rapidly disintegrating tablets of metoclopramide hydrochloride using novel chemically modified cellulose
... purpose of the study was to modify cellulose using hydrochloride salt of 2-aminoethanoyl chloride with optimum hydrophilic and hydrophobic properties to impart it a superdisintegrant activity ... See full document
10
Evaluation of biodegradable implants based on polymer blends: development, characterization and in vitro release studies
... Implants prepared with polymer blends [poly (e-caprolactone)-poly(lactide), PCL-PLA] at different rates were developed from microspheres. Approximately 19% of dexamethasone acetate was e[r] ... See full document
1
Effect of Different Hydrophillic Binders on the Dissolution Profiles of Mefenamic Acid
... The aim of this study was to elaborate the effect of hydrophilic binders on the release profiles of matrix tablets containing mefenamic acid.. Mefenamic acid tablets were prepared using [r] ... See full document
1
Preparation and characterisation of controlled release ciprofloxacin HCl microspheres
... The prepared micro- spheres were characterized by FT-IR spectroscopy, differential scanning colorimetry for drug polymer compatibility studies and scanning electron microscopy for surfac[r] ... See full document
1
Elastin like polypeptides in drug delivery
... required and its turn- over. The drug depot approach offers the possibility of formulation in multiple dosage forms to calibrate the delivery strategies and provide a suitable alternative for ... See full document
46
Formulation and evaluation of Theophylline controlled release matrix tablets using Guar gum
... design tablets and tablet production quality test, the formulated tablets were evaluated for thickness and diameter (using a vernier caliper), hardness test (using Monsanto hardness tester) 10 ... See full document
10
Development and in vitro evaluation of propranolol hydrochloride controlled release tablets using HPMC as matrix former
... Taking into account that PHCl is a very soluble drug, low concentrations (15 %) of HPMC were sufficient to reduce the drug release and to promote controlled release of PHCl, presenting g[r] ... See full document
1
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