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[PDF] Top 20 Development and in vitro evaluation of propranolol hydrochloride controlled release tablets using HPMC as matrix former

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Development and in vitro evaluation of propranolol hydrochloride controlled release tablets using HPMC as matrix former

Development and in vitro evaluation of propranolol hydrochloride controlled release tablets using HPMC as matrix former

... Taking into account that PHCl is a very soluble drug, low concentrations (15 %) of HPMC were sufficient to reduce the drug release and to promote controlled release of PHCl, presenting g[r] ... See full document

1

Formulation and evaluation of oral sustained release of Diltiazem Hydrochloride using rosin as matrix forming material

Formulation and evaluation of oral sustained release of Diltiazem Hydrochloride using rosin as matrix forming material

... used as a hydrophobic matrix material for the controlled release, using diltiazem HCl as model ...drug. Matrix tablets were prepared by direct compression method ... See full document

11

Development and characterization of controlled release mucoadhesive tablets of captopril

Development and characterization of controlled release mucoadhesive tablets of captopril

... the development of mucoadhesive tablets of Captopril which were designed to prolong the gastric residence time after oral ...administration. Matrix tablets of Captopril ... See full document

8

Formulation and evaluation of controlled release matrix tablet of diltiazem HCl by using HPMC and guar gum as polymeric matrix material

Formulation and evaluation of controlled release matrix tablet of diltiazem HCl by using HPMC and guar gum as polymeric matrix material

... increased as the concentration and viscosity of HPMC ...increases. Tablets formulated using guar gum and HPMC alone were gave initial burst effect followed by ... See full document

6

Fabrication and in vitro evaluation of subgingival strips of calcium alginate for controlled delivery of ofloxacin and metronidazole

Fabrication and in vitro evaluation of subgingival strips of calcium alginate for controlled delivery of ofloxacin and metronidazole

... determination of OFX and MET in pH ...correlation and linearity for both the drugs. Strips can be prepared using solvent casting ...technique. As drug concentration was increased ... See full document

9

Effect of Different Hydrophillic Binders on the Dissolution Profiles of Mefenamic Acid

Effect of Different Hydrophillic Binders on the Dissolution Profiles of Mefenamic Acid

... The aim of this study was to elaborate the effect of hydrophilic binders on the release profiles of matrix tablets containing mefenamic acid.. Mefenamic acid tablets were prepared using [r] ... See full document

1

Development of gliclazide matrix tablets from pure and blended mixture of glyceryl monostearate and stearic acid

Development of gliclazide matrix tablets from pure and blended mixture of glyceryl monostearate and stearic acid

... Matrix tablets for the controlled de- livery of gliclazide were prepared by hot melt method using pure and blended mixture of glyceryl monos- tearate and stearic acid in different drug t[r] ... See full document

1

Study of drug release retardant capability of hydroxypropylmethylcellulose and carbopol in matrix tablets

Study of drug release retardant capability of hydroxypropylmethylcellulose and carbopol in matrix tablets

... The present study was undertaken to investigate the effect of nature of polymers like HPMC, carbopol-934P and their content levels on the release profiles of water soluble drug, diclofen[r] ... See full document

1

Formulation and Evaluation of Sustained Release Tablets of Metformin Hydrochloride by Solid Dispersion Technique Using pH dependent and pH independent Eudragit Polymers

Formulation and Evaluation of Sustained Release Tablets of Metformin Hydrochloride by Solid Dispersion Technique Using pH dependent and pH independent Eudragit Polymers

... Drug release studies were conducted using USP-22 dissolution apparatus-2, paddle type (Electrolab, Mumbai, India) at a rotational speed of 50 rpm at ...intervals and the same volume of ... See full document

10

Preparation and evaluation of modified release zidovudine tablets

Preparation and evaluation of modified release zidovudine tablets

... The calculated release ex- ponent pointed out that formulations follow the anomalous type of release mechanism, with a combined phenomena of diffusion and erosion..[r] ... See full document

1

Alginate/hydrophobic HPMC (60L) particulate systems: new matrix for controlled release of diclofenac potassium

Alginate/hydrophobic HPMC (60L) particulate systems: new matrix for controlled release of diclofenac potassium

... This work is focused on the development of a new particulate drug delivery system using sodium alginate (SA) and modified hydrophobic hydroxyl propyl methyl cellulose (HPMC, 60L grade) c[r] ... See full document

1

Hypromelose / polyethylene oxide (PEO) matrix tablets for oral sustained Aacyclovir release: formulation aspects and release behavior

Hypromelose / polyethylene oxide (PEO) matrix tablets for oral sustained Aacyclovir release: formulation aspects and release behavior

... Matrix tablets obtained in each formulation were evaluated to determine the weight variation, thickness, hardness, drug content, swelling and erosion and in vitro release. The swelling [r] ... See full document

1

In vitro evaluation of commercially available theophylline sustained release tablets in Pakistan

In vitro evaluation of commercially available theophylline sustained release tablets in Pakistan

... For predicting the release characteristics of theophylline from selected com- mercially available tablets the data obtained in the dissolution studies was fitted into various mathematic [r] ... See full document

1

Development and characterization of controlled release mucoadhesive tablets of captopril to increase the residence time in the gastrointestinal tract

Development and characterization of controlled release mucoadhesive tablets of captopril to increase the residence time in the gastrointestinal tract

... It was evident from the study that the for- mulation F10 containing HPMC K15M and xanthan gum (1:1) exhibited maximum bioadhesive strength of 31.59 ± 0.05 gm and in vitro drug release wa[r] ... See full document

1

Evaluation of biodegradable implants based on polymer blends: development, characterization and in vitro release studies

Evaluation of biodegradable implants based on polymer blends: development, characterization and in vitro release studies

... Implants prepared with polymer blends [poly (e-caprolactone)-poly(lactide), PCL-PLA] at different rates were developed from microspheres. Approximately 19% of dexamethasone acetate was e[r] ... See full document

1

Monitoring ibuprofen enantiomers released from polymeric systems / C  Barbas     [et al ]

Monitoring ibuprofen enantiomers released from polymeric systems / C Barbas [et al ]

... structures of the precursor monomers bearing IBU used to synthesize the polymeric devices are represented in ...synthesis and characterization of copolymers of these two methacrylic ... See full document

8

Venlafaxine hydrochloride transdermal patches: effect of hydrophilic and hydrophobic matrix on in vitro characteristics

Venlafaxine hydrochloride transdermal patches: effect of hydrophilic and hydrophobic matrix on in vitro characteristics

... systems of venlafaxine hydrochloride were prepared by using combination of hydrophilic (HPMC E15) and hydrophobic (ERS100 and ERL 100) polymers in 1:5, 2:4, 3:3, ... See full document

1

Formulación y evaluación de comprimidos matriciales de clorhidrato de ambroxol, usando un polímero natural hidrofílico

Formulación y evaluación de comprimidos matriciales de clorhidrato de ambroxol, usando un polímero natural hidrofílico

... Se realizaron estudios de liberación de fármaco in vitro mediante un aparato de disolución USP XXIV tipo II con 900 ml de medio de disolución mantenido a 37±1° C durante 12 horas a 100 rpm. Durante las 2 ... See full document

12

Formulation development and Optimization of Diclofenac Sodium Extended release Matrix tablets as per USP standards

Formulation development and Optimization of Diclofenac Sodium Extended release Matrix tablets as per USP standards

... Materials and Methods: The extended release tablets of Diclofenac sodium was prepared by using different concentration of polymers such as hydroxyl propyl methyl cellulose ... See full document

7

Formulation and evaluation of gliclazide loaded controlled release microspheres

Formulation and evaluation of gliclazide loaded controlled release microspheres

... The effect of different formulation variables (drug-polymer ratio and polymer-polymer ratio) on percent yield, mean particle size, encapsulation efficiency and in vitro release of drug w[r] ... See full document

1

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