[PDF] Top 20 Metabolomic profiles of hepatocellular carcinoma in a European prospective cohort.

... its prospective design, availability of detailed pre-diagnostic lifestyle/dietary data, and an- thropometric measures, additional strengths of our study include the ability to consider liver function ... See full document

... cause of chronic liver disease, including cir- rhosis and hepatocellular carcinoma in Western Coun- ...million of people infected world-wide), the lack of symptoms during the ... See full document

... with hepatocellular carcinoma ...included in the prospective Bern HCC cohort were ...ed in the cohort, 116 were not treated according to the BCLC ...percent of the ... See full document

... cause of HCC in the overall cohort (37%), followed by HBV (25%) and alcoholic liver dis- ease ...48% in 2005—06 to 26% in 2011—12, NAFLD increased from ...cause of HCC. This ... See full document

... longer. In the course of time, hepatocellular carcinoma (HCC) began to be found in these ...risk of developing ...incidence of HCC in hepatitis C cirrhotic patients ... See full document

... EPIC cohort, aiming at studying the relationship between select cancer types and air pollution or environmental tobacco ...analysis of questionnaire data, and two controls per case for laboratory ...country ... See full document

... results of upreg- ulated (Figure 2a) and downregulated (Figure 2b) miR- NAs in ...variations in methodologies or in the sample origin spanning different geographical regions and ethnic ... See full document

... opment of hepatocellular carcinoma ...incidence of obesity, at least in some resource-rich countries, has been the predominant reason for the striking increase in the incidence ... See full document

... based of the expression level of its mRNA or DNA) were ...specificity of GPC3. Finally, a total of 11 studies were eligible 8-11,19-25 (Figure ... See full document

... one of the liver-related causes of death in subjects with ...results of the Roches- ter Epidemiology Project, which included subjects with biopsy-proven (17%) and without biopsy-proven NAFLD ... See full document

... The prognostic models should be as calibrated as pos- sible to the study population. On the one hand, our cali- bration analysis showed that all the models had justification to be applied in this population, ... See full document

... study of hepatocarcinogenesis in monozygotic twins represents an important contribution to the clarification of the HCC pathogenesis because of them sharing the same genetic code and ... See full document

... Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading cause of cancer deaths in ...differences in the prevalence of viral hepatitis, the incidence ... See full document

... El carcinoma hepatocelular (CHC) es un tumor primario del hígado asociado a cirrosis en 90% de los casos. Constituye la quinta causa de cáncer a nivel mundial en hombres y la séptima en mujeres. Tiene una ... See full document

... differences in HCC between regions cannot always be explained by different ...history of alcohol abuse and survival was also lower when alcohol abuse was associated with HCV ...reported in the study ... See full document

... incidence in sub-Saharan Africa and ...found in up to 80 per cent of cases of the disease is ...percent of these tumors are the biologic consequences of persistent hepatitis B ... See full document

... analyses of OC use, we observed a lower risk for all-cause, total cancer, and circulatory disease mortality with ever versus never use of OCs among non-smokers; this finding is consistent with two studies ... See full document

... participates in the antiproliferative effect evoked by ...PPARg in HepG2 cells. 18 Moreover, in previous studies, we demon- strated that cannabinoids induce apoptosis and autophagy in HCC ... See full document

... revision of the data was centrally requested, and investigators who performed the final analysis did not participate in the data collection to avoid differential outcome assessment on ...time of ... See full document

... agnosis of HCC, was remarkably higher in the group of patients who developed HCC than in pa- tients who did not develop HCC during the same period of follow-up, while AFP increase was ... See full document