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[PDF] Top 20 Synthesis and antiproliferative activity of new cyclodiprenyl phenols against select cancer cell lines

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Synthesis and antiproliferative activity of new cyclodiprenyl phenols against select cancer cell lines

Synthesis and antiproliferative activity of new cyclodiprenyl phenols against select cancer cell lines

... avinosol and avarol offer promising opportunities for the development of new antitumor agents ...potential of meroterpenes is of great interest; however, low yields of these ... See full document

13

Synthesis, Antifungal and Antitumor Activity of Novel (Z)-5-Hetarylmethylidene-1,3-thiazol-4-ones and (Z)-5-Ethylidene-1,3-thiazol-4-ones

Synthesis, Antifungal and Antitumor Activity of Novel (Z)-5-Hetarylmethylidene-1,3-thiazol-4-ones and (Z)-5-Ethylidene-1,3-thiazol-4-ones

... Abstract: New hetaryl- and alkylidenerhodanine derivatives 3a–d, 3e, and 4a–d were prepared from heterocyclic aldehydes 1a–d or acetaldehyde ...treatment of several rhodanine derivatives 3a–d ... See full document

16

Effective potential studies for some new hybrid molecules for their activity against prostate cancer

Effective potential studies for some new hybrid molecules for their activity against prostate cancer

... the antiproliferative activity of newly developed compounds was found to the most accurate and suitable method for evaluation of these ...accurate and specific for testing ... See full document

12

Aislamiento, Modelización y Fitossomas de Compuestos Antimicrobianos y Antiproliferativos de Plectranthus SPP

Aislamiento, Modelización y Fitossomas de Compuestos Antimicrobianos y Antiproliferativos de Plectranthus SPP

... 9. Antiproliferative compounds obtained from Plectranthus ...regulatory and catalytic ...structure of some natural products that act as PKC isoforms ...structure of the PdC, representative PdC ... See full document

239

Validation of suitable normalizers for miR expression patterns analysis covering tumour heterogeneity.

Validation of suitable normalizers for miR expression patterns analysis covering tumour heterogeneity.

... isolation and Quantitaitve Real Time Polimerase Chain Reaction ...different cell lines and subpopulations using the miRNeasy Mini Kit (Qiagen, Limburgo, Netherland) following manufacturer´s ... See full document

9

Synthesis and cytotoxic activity of per acetylated and halogenated derivatives of nucleosides in breast cancer cells

Synthesis and cytotoxic activity of per acetylated and halogenated derivatives of nucleosides in breast cancer cells

... overlapping of H-5’ and H-6’ protons of ribose ring) with a high deshielding signal ...(H-4’) and other highly deshield- ed signal ...(H-2’) of the ribose ...H-5’ and H-6’protons ... See full document

10

Pre  and post infection activity of new funguicides against Botrytis cinerea and other fungi causing decay of table grapes

Pre and post infection activity of new funguicides against Botrytis cinerea and other fungi causing decay of table grapes

... Torres, and B.A. Latorre. 2007. Pre- and post-infection activity of new fungicides against Botrytis cinerea and other fungi causing decay of table ...Pre- ... See full document

10

Synthesis and cytotoxic activity of tri acyl ester derivatives of uridine in breast cancer cells

Synthesis and cytotoxic activity of tri acyl ester derivatives of uridine in breast cancer cells

... concentrations of 1, 10 and 100 µM of uridine or derivatives, were incubated for 48 hours at 37°C for 48 ...µL of MTT (5 mg/ mL, Sigma) were added, and the plates were incubated in ... See full document

9

Hemi Synthesis and Anti Oomycete Activity of Analogues of Isocordoin

Hemi Synthesis and Anti Oomycete Activity of Analogues of Isocordoin

... efficient synthesis of a series of 4 0 -oxyalkyl-isocordoin analogues (2–8) is reported for the first ...C-NMR, and HRMS. Their anti-oomycete activity was evaluated by mycelium ... See full document

9

Enhanced antitumor activity of doxorubicin in breast cancer through the use of poly(butylcyanoacrylate) nanoparticles.

Enhanced antitumor activity of doxorubicin in breast cancer through the use of poly(butylcyanoacrylate) nanoparticles.

... loading, and at similar dilutions to drug-loaded NPs). Cytotoxic activity was assessed by deter- mining the 50% inhibitory concentration (IC 50 ) values obtained from the ... See full document

16

Enhanced caveolin 1 expression increases migration, anchorage independent growth and invasion of endometrial adenocarcinoma cells

Enhanced caveolin 1 expression increases migration, anchorage independent growth and invasion of endometrial adenocarcinoma cells

... DNAase and employed as templates to generate cDNA using M-MLV Reverse ...) and β -actin (sense primer 5 ′ - TGG CAC CCA GCA CAA TGA AGA -3 ′ ; anti- sense primer 5 ′ - GAA GCA TTT GCG GTG GAC GAT -3 ′ ) ... See full document

11

Rhythmic profile assessment of breast cancer cell lines and adipose derived stem cells after circadian entrainment

Rhythmic profile assessment of breast cancer cell lines and adipose derived stem cells after circadian entrainment

... 2013) and Nanog (Seymour et al., 2015). The identification of this specific expression related to stemness should guide into a proteomic way of behavior, ...genomic of stem cells is closely ... See full document

62

Design and Synthesis of Pironetin Analogue/Combretastatin A 4 Hybrids and Evaluation of Their Cytotoxic Activity

Design and Synthesis of Pironetin Analogue/Combretastatin A 4 Hybrids and Evaluation of Their Cytotoxic Activity

... structures and the observed cytotoxicity deserve comment. In the case of two subsets of hybrid molecules [27] where there are differences between in the carbon chain length ...1-4 and 5-8), ... See full document

18

Synthesis and cytotoxic activity of geranylmethoxyhydroquinone derivatives

Synthesis and cytotoxic activity of geranylmethoxyhydroquinone derivatives

... the new synthetic geranyl-2,4- methoxyhydroquinone 1 and known geranyl-4,5-methoxyhydroquinone ...obtained of the chemical transformations of the compounds coupling 1 and ...cytotoxic ... See full document

5

Bisphenol A and Nonylphenol Induce Apoptosis in Reproductive Tract Cancer Cell Lines by the Activation of ADAM17

Bisphenol A and Nonylphenol Induce Apoptosis in Reproductive Tract Cancer Cell Lines by the Activation of ADAM17

... name of a wide variety of compounds that disrupt the internal hormonal balance in humans and wildlife animals, leading to transient and/or permanent negative effects ...(BPA) and ... See full document

18

Hormona liberadora de la hormona del crecimiento (GHRH) y sus antagonistas en la progresión del cáncer de próstata

Hormona liberadora de la hormona del crecimiento (GHRH) y sus antagonistas en la progresión del cáncer de próstata

... The expression of growth hormone-releasing hormone GHRH and its receptor splice variants in human breast cancer lines; the evaluation of signaling mechanisms in the stimulation of cell p[r] ... See full document

277

TRPM4 regulates Akt/GSK3 β activity and enhances β catenin signaling and cell proliferation in prostate cancer cells

TRPM4 regulates Akt/GSK3 β activity and enhances β catenin signaling and cell proliferation in prostate cancer cells

... levels and b - catenin stability and function in prostate cancer cell ...the activity of GSK-3b in TRPM4-knockdown cells is shown to correlate with a reduction in the total ... See full document

15

Efectos antineoplásicos de nuevos análogos del 1α,25(OH)_2vitamina D_3

Efectos antineoplásicos de nuevos análogos del 1α,25(OH)_2vitamina D_3

... Wen P.Y., Yung W.K., Lamborn K.R., Dahia P.L., Wang Y., Peng B., Abrey L.E., Raizer J., Cloughesy T.F., Fink K., Gilbert M., Chang S., Junck L., Schiff D., Lieberman F., Fine H.A., Mehta M., Robins H.I., DeAngelis L.M., ... See full document

45

Antiproliferative activity of haematoxy brasiletto H-Karst.

Antiproliferative activity of haematoxy brasiletto H-Karst.

... well of a flat 96-well ...atmosphere of 5% CO 2 to allow cell attachment, the cell cultures were incubated with 50 µL of medium containing different concentrations of either ... See full document

5

Cytotoxic, antiangiogenic and antitelomerase activity of glucosyl  and acyl  resveratrol prodrugs and resveratrol sulfate metabolites

Cytotoxic, antiangiogenic and antitelomerase activity of glucosyl and acyl resveratrol prodrugs and resveratrol sulfate metabolites

... 2 and 3 and show that treatment of HT-29 cells with resveratrol and the aforementioned derivatives leads in fact to various degrees of reduction in the transcription of hTERT ... See full document

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