[PDF] Top 20 Synthesis and cytotoxic activity of tri acyl ester derivatives of uridine in breast cancer cells
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Synthesis and cytotoxic activity of tri acyl ester derivatives of uridine in breast cancer cells
... ly, in DMEM or F-12 medium were supplemented with 5% ...concentrations of 1, 10 and 100 µM of uridine or derivatives, were incubated for 48 hours at 37°C for 48 ...µL of ... See full document
9
Synthesis and cytotoxic activity of geranylmethoxyhydroquinone derivatives
... inhibitory activity, ranged in the 80 µM level for breast cancer cell line MDA-MB-231, these values may be due to the presence of a quinone ...moiety. In the case of the ... See full document
5
SYNTHESIS OF GERANYLHYDROQUINONE DERIVATIVES WITH POTENCIAL CYTOTOXIC ACTIVITY
... 1 and geranyl-p-methoxyphenol 2 were prepared by Electrophilic Aromatic Substitution (EAS) reactions between geraniol and 1,4-hydroquinone or p-methoxyphenol respectively, using BF 3 ∙Et 2 O as a ...4 ... See full document
10
Synthesis and cytotoxic activity of per acetylated and halogenated derivatives of nucleosides in breast cancer cells
... NCS and NBS allowed the selective substitution on the 5-position of uracil and cyto- sine ring of each nucleoside with quantitative ...reagent and solvent does not require heating or ... See full document
10
Hemi Synthesis and Anti Oomycete Activity of Analogues of Isocordoin
... efficient synthesis of a series of 4 0 -oxyalkyl-isocordoin analogues (2–8) is reported for the first ...C-NMR, and HRMS. Their anti-oomycete activity was evaluated by mycelium ... See full document
9
Enhanced antitumor activity of doxorubicin in breast cancer through the use of poly(butylcyanoacrylate) nanoparticles.
... use of doxorubicin (DOX), one of the most effective antitumor molecules in the treatment of metastatic breast cancer, is limited by its low tumor selectivity and its ... See full document
16
Sobrediagnóstico de cáncer de mama en el cribado con mamografía. Salud pública, clínica y ética
... Public knowledge of benefits of breast and prostate cancer screening in Europe. A survey study of women’s responses to information[r] ... See full document
12
Capacidad atrapadora de radicales libres, efectos citotxicos y antiproliferativos de Vaccinium meridionale Sw en lneas celulares de cncer de colon
... used in all work, HPLC - grade acetonitrile, phosphoric and formic acid (Merck , Darmstadt, Germany) were used after filtration through a ...Methanol and other HPLC solvents were from were purchased ... See full document
13
Bioenergetics mechanism and autophagy in breast cancer stem cells
... growth in soft agar and tumor formation in nude mice, partially establishing a causal role of autophagy induction in malignant transformation (Soung, Lee et ...proliferation and ... See full document
305
Design and Synthesis of Pironetin Analogue/Colchicine Hybrids and Study of Their Cytotoxic Activity and Mechanisms of Interaction with Tubulin
... Total synthesis of (−)-PA-48153C, a novel immunosuppressive 2- pyranone ...Total synthesis of a potent immunosuppressant ...Total synthesis of (−)-PA-48153C (pironetin) utilising ... See full document
14
La metformina como una alternativa en la prevencin y tratamiento del cncer
... 45. Giovannucci E, Harlan DM, Archer MC, Bergenstal RM, Gapstur SM, Habel LA, et al. Diabetes and Cancer: A Consensus Report. CA Cancer J Clin. 2010;60:207-21. 46. Yun J, Rago C, Cheong I, Pagliarini ... See full document
11
Actividad antiparasitaria in vitro citotxica de cariofileno y eugenol contra Trypanosoma cruzi y Leishmania brasiliensis
... Resazurina sal de sódio foi obtido de Sigma-Aldrich (St. Louis, MO), e armazenadas a 4 °C protegidos da luz. Uma solução de resazurina foi preparada em tampão de fosfato a 1 %, pH 7, e esterilizado por filtração antes da ... See full document
7
CELULAS DENDRITICAS EPIDERMICAS Thy-1 POSITIVAS UN NUEVO GRUPO CELULAR ASOCIADO CON INMUNOVIGILANCIA CUTANEA
... experimentos in vitro han demostrado que estas celulas presentan citotoxicidad frente a grupos de células ...pruebas in vivo demuestran que las CDE Thy-1 ejercen una función derreguladora en las respuestas ... See full document
6
Consumo de alcohol y riesgo de cncer de mama
... alcohol and estrogen replacement therapy on risk of breast cancer differs by estrogen/progesterone receptor status in the Iowa Women’s Health ...Study. Cancer Epidemiol ... See full document
8
Implicaciones de la inestabilidad cromosómica y heterogeneidad clonal en la respuesta a la terapia en cáncer de seno
... that in KPL4 cells an CIN greater than 69% was related to sensitivity or response to therapy, it could be suggested that an increase in the dose of the treatments (applied in ... See full document
95
Prevention and treatment of osteoporosis in multiple myeloma, early stages of breast cancer and prostate cancer
... aim of this review is to discuss recent findings in the physiopathology and treatment of osteoporotic le- sions present in almost all patients with ...efficacy of bisphosphonates ... See full document
7
In vitro trypanocidal activity of nitroimidazole derivatives
... million of people in Latin America and it is an important cause of heart ...nitroimidazole derivatives [4(5)-bromo-1-phenacyl-5(4)-nitroimidazoles] were developed and their ... See full document
1
Drug delivery systems based on poly(e caprolactone) for cancer treatment
... over cancer cells, resulting in low therapeutic concentrations at the tumor site (a consequence of a broad systemic distribution), and severe side ...aim of avoiding ... See full document
14
Design and Synthesis of Pironetin Analogue/Combretastatin A 4 Hybrids and Evaluation of Their Cytotoxic Activity
... structures and the observed cytotoxicity deserve comment. In the case of two subsets of hybrid molecules [27] where there are differences between in the carbon chain length ...1-4 ... See full document
18
Sam68 Mediates the Activation of Insulin and Leptin Signalling in Breast Cancer Cells.
... for breast cancer development in postmenopausal ...insulin and leptin levels seem to have a role modulating the growth of these ...overexpressed in breast ...insulin ... See full document
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