[PDF] Top 20 Wnt 5a/JNK Signaling Promotes the Clustering of PSD 95 in Hippocampal Neurons
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Wnt 5a/JNK Signaling Promotes the Clustering of PSD 95 in Hippocampal Neurons
... During the formation of synapses, specific regions of pre- and postsynaptic cells associate to form a single functional transmis- sion ...unit. In this process, synaptogenic factors are ... See full document
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Wnt signaling in the regulation of adult hippocampal neurogenesis
... non-canonical Wnt pathways have relevant roles in the adult ...hippocampus. In cultured hip- pocampal neurons, the Wnt-5a ligand able to activate non- canonical ... See full document
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Wnt 5a occludes A beta oligomer induced depression of glutamatergic transmission in hippocampal neurons
... washing the Ab oligomers and did not affect the presynaptic machinery of neurotransmitter ...affect the postsynaptic region ...including the PSD-95, by a mechanism that ... See full document
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Wnt signalling in neuronal differentiation and development
... to the participation in neuronal polarization and morphogenesis, it is known that Wnt signalling regulates syn- apse formation and ...recordings in rat hippocampal slices showed that a ... See full document
10
Involvement of WNT signaling pathway in the adult hippocampal synapses :role in neuroprotection
... At the cellular level, Wnt signaling plays an important role in controlling neuronal connectivity through the regulation of neuronal polarity, axonal remodeling, dendritic ... See full document
137
Modulation of the NMDA Receptor Through Secreted Soluble Factors
... context, Wnt-5a also exhibits a protective role against the reduced expression of NMDAR and PSD-95 through A β oligomers ...Indeed, Wnt-5a occludes the ... See full document
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Wnt 5a Modulates Recycling of Functional GABA(A) Receptors on Hippocampal Neurons
... The Wnt signaling pathway has been involved in various cel- lular processes, including functions in the neuronal development and maintenance of the nervous system ... See full document
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Wnt/β catenin signaling stimulates the expression and synaptic clustering of the autism associated Neuroligin 3 gene
... described in individuals with autism spectrum disorders (ASD). The cell-adhesion molecule Neuroligin-3 (Nlgn3) has an essential role in the function and maturation of synapses and NLGN3 ... See full document
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Wnt related synGAP1 is a neuroprotective factor of glutamatergic synapses against Aß oligomers
... The signaling pathways mediated through Wnt have been implicated in various cellular processes, including cell proliferation, migration, establishment of polarity, cell fate ... See full document
11
Wnt 7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons
... pendent of GSK-3  activity and  -catenin ...blot of hippocampal neurons stimulated with Wnt-5a, Wnt-7a, or pcDNA (control) for 1 h show that only Wnt-7a ligand ... See full document
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PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B NMDA receptors
... that the NMDA receptor (NMDAR) subunits NR2A and NR2B are critical mediators of synaptic plasticity and dendritogenesis; however, how they differentially regulate these processes is ...investigate ... See full document
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WNT signaling in neuronal maturation and synaptogenesis
... increase the number of presynaptic puncta suggesting a role for these ligands in presynaptic assembly (Ahmad-Annuar et ...increases the clustering of presynaptic proteins such as ... See full document
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Role of the Wnt receptor Frizzled 1 in presynaptic differentiation and function
... activation of the canonical and non-canonical pathways differentially modulates pre- and postsynaptic ...events. The non-canoni- cal ligand Wnt-5a induces the clustering ... See full document
15
The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease
... plethora of cofactors and regulators are known. Different mechanisms of Wnt sign- aling have also been ...identified. The best understood of these is the "canonical" ... See full document
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In vivo activation of Wnt signaling pathway enhances cognitive function of adult mice and reverses cognitive deficits in an Alzheimer's disease model
... activation of Wnt/-catenin signaling can modulate amygdala-dependent fear memory for- mation (Maguschak and Ressler, 2008, ...activation of Wnt signaling could also participate ... See full document
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Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20 APP transgenic and wild type mice
... increase the levels of the Wnt7a/b and Wnt5a ligands in the rat hippocampus (Tabatadze et ...canonical Wnt signaling is necessary for hippocampal memory ... See full document
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A novel function for Wnt signaling modulating neuronal firing activity and the temporal structure of spontaneous oscillation in the entorhinal hippocampal circuit
... study the effect of Wnt analogues we fi rst developed an in vitro slice preparation where we can record the spontaneous oscillations in three regions of a well-preserved ... See full document
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Wnt 7a induces presynaptic colocalization of alpha 7 nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons
... roles of APC in short- and longer-term effects of Wnt-7a on cluster- ing of APC and ␣7-nAChR in presynaptic terminals, we examined effects of siRNA knockdown of ... See full document
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Efecto de HOTAIR sobre TET1 y la vía WNT en la línea celular HeLa.
... vía WNT, la cual induce la expresión de genes involucrados en migración, proliferación e invasión ...vía WNT. Hasta el momento se desconoce si HOTAIR regula la vía WNT a traves de TET1, por lo que el ... See full document
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Physiological Control of Nitric Oxide in Neuronal BACE1 Translation by Heme Regulated eIF2 alpha Kinase HRI Induces Synaptogenesis
... is the brain center for memory formation, a process that requires ...compromised in Alzheimer’s disease due to the accumulation of amyloid b-peptide, whose production is initiated by b-site ... See full document
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