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[PDF] Top 20 WNT signaling in neuronal maturation and synaptogenesis

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WNT signaling in neuronal maturation and synaptogenesis

WNT signaling in neuronal maturation and synaptogenesis

... involved in dendrite formation, maintenance, and functioning during the last decade is Wnt ...that Wnt factors modulate axon morphology and branching prob- ably because they affect the ... See full document

11

A novel function for Wnt signaling modulating neuronal firing activity and the temporal structure of spontaneous oscillation in the entorhinal hippocampal circuit

A novel function for Wnt signaling modulating neuronal firing activity and the temporal structure of spontaneous oscillation in the entorhinal hippocampal circuit

... early and late postnatal developments, the establishment of functional neuronal connectivity depends on molecules like Wnt that help the recently formed synapses to establish and consolidate ... See full document

13

Wnt signaling in skeletal muscle dynamics: Myogenesis, neuromuscular synapse and fibrosis

Wnt signaling in skeletal muscle dynamics: Myogenesis, neuromuscular synapse and fibrosis

... identity and function of proteins regulating the presyn- aptic differentiation of motor neurons have not been extensive- ly described; however, genetic in vivo studies have identified important regulators ... See full document

16

Canonical Wnt signaling protects hippocampal neurons from A beta oligomers: role of non canonical Wnt 5a/Ca2+ in mitochondrial dynamics

Canonical Wnt signaling protects hippocampal neurons from A beta oligomers: role of non canonical Wnt 5a/Ca2+ in mitochondrial dynamics

... loss and mitochondrial dysfunction. The Wnt signaling pathway participates in the development of the central nervous system and growing evidence indicates that Wnts also regulate the ... See full document

12

Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20 APP transgenic and wild type mice

Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20 APP transgenic and wild type mice

... non-canonical Wnt signal- ing depends on the cellular context and ligand-receptor binding and is not dependent on the ligand itself (Mikels and Nusse 2006; Grumolato et ...However, Wnt ... See full document

23

Wnt signaling in the regulation of adult hippocampal neurogenesis

Wnt signaling in the regulation of adult hippocampal neurogenesis

... non-canonical Wnt pathways have relevant roles in the adult hippocampus. In cultured hip- pocampal neurons, the Wnt-5a ligand able to activate non- canonical Wnts cascades (Farias et ...roles ... See full document

11

Signaling pathway cross talk in Alzheimer's disease

Signaling pathway cross talk in Alzheimer's disease

... failure and accumulative intracellular waste play a causal role in the pathogenesis of several neurodegenerative disorders and Alzheimer ’ s disease (AD) in ...inflammation and ... See full document

12

Wnt 5a/JNK Signaling Promotes the Clustering of PSD 95 in Hippocampal Neurons

Wnt 5a/JNK Signaling Promotes the Clustering of PSD 95 in Hippocampal Neurons

... increase in the clustering of PSD-95 induced by the Wnt-5a ligand is correlated with the increase in mature den- dritic spines with PSD-95 positive in their heads, suggesting that the ... See full document

11

Involvement of WNT signaling pathway in the adult hippocampal synapses :role in neuroprotection

Involvement of WNT signaling pathway in the adult hippocampal synapses :role in neuroprotection

... level, Wnt signaling plays an important role in controlling neuronal connectivity through the regulation of neuronal polarity, axonal remodeling, dendritic morphogenesis and ... See full document

137

Regulation of NMDA Receptor Synaptic Transmission by Wnt Signaling

Regulation of NMDA Receptor Synaptic Transmission by Wnt Signaling

... CaMKII and PKC, two enzymes involved in controlling synaptic function and plasticity (Veeman et ...Kohn and Moon, 2005; Gordon and Nusse, 2006). Wnt proteins participate ... See full document

6

Wnts in adult brain: from synaptic plasticity to cognitive deficiencies

Wnts in adult brain: from synaptic plasticity to cognitive deficiencies

... changes in the synaptic connectivity such as the imbalance between excitation/inhibition may result into a cascade of multiple effects at the neural network level which in many cases precedes cell ... See full document

16

WASP 1, a canonical Wnt signaling potentiator, rescues hippocampal synaptic impairments induced by A beta oligomers

WASP 1, a canonical Wnt signaling potentiator, rescues hippocampal synaptic impairments induced by A beta oligomers

... of Wnt/ β -catenin signaling and an increase in A β -related neurotoxicity (De Ferrari et ...Inestrosa and Arenas, 2010). Speci fi cally, loss of Wnt/ β -catenin signaling ... See full document

12

Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum

Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum

... Mayeux and Stern, ...processing and is characterized by the presence of extracellular aggregates of amyloid- b peptide (A b ) called senile plaques and by intracellular clusters of ... See full document

22

Wnt signaling: Role in LTP, neural networks and memory

Wnt signaling: Role in LTP, neural networks and memory

... that Wnt molecules are involved in gene expression and structural plasticity, almost rules out the possibility of an immediate and dynamic ...feature in neu- ronal physiology, such as ... See full document

15

Wnt Signaling: Role in Alzheimer Disease and Schizophrenia

Wnt Signaling: Role in Alzheimer Disease and Schizophrenia

... of Wnt signaling cannot only be attributed to a loss of function. In fact, the reduction in the Wnt signal- ing can be due to a gain of function of inhibitors of the Wnt ... See full document

20

Wnt signalling in neuronal differentiation and development

Wnt signalling in neuronal differentiation and development

... system, Wnt signalling cascades are impor- tant for the formation of neuronal ...ment, Wnt signalling regulates self-renewal, maintenance and differentiation of neural progenitor cells ... See full document

10

The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease

The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease

... between Wnt signaling and ...AD in populations with inheritance of the apo-lipoprotein E-ε4 (APOE-ε4) allele, including both sporadic and late-onset familial forms of the disease ... See full document

13

Wnt signaling in the nervous system and in Alzheimer's disease

Wnt signaling in the nervous system and in Alzheimer's disease

... a signaling cascade that regulates several aspects of develop- ment including organogenesis, midbrain development as well as stem cell ...proliferation. Wnt signaling pathway plays different roles ... See full document

11

What Do We Really Know About 5 HT1A Receptor Signaling in Neuronal Cells?

What Do We Really Know About 5 HT1A Receptor Signaling in Neuronal Cells?

... (Albert and Tiberi, ...or in combination with other ...development and are dynamically regulated postnatally, suggesting a pivotal role during brain development (Gaspar et ...2003). In the ... See full document

8

Molecular Markers in Thyroid Cancer 

Molecular Markers in Thyroid Cancer 

... discovered in thyroid cancer in the last years, emphasizing by example BRAF and RAS genes (KRAS, HRAS, NRAS) as well as RET- PTC and receptor tyrosine kinases (TRK) rear- rangements, all of ... See full document

15

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