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APROXIMACIÓN DEL PROBLEMA

1. PLANTEAMIENTO DEL PROBLEMA

1.1. APROXIMACIÓN DEL PROBLEMA

Optical imaging modalities designed for imaging of epithelial cancer, specifically oral and colorectal, have been widely studied due to their wide range of applications. Contrast agents are a crucial component of optical imaging design, whether exogenous or endogenous. We analyzed the morphology of oral and colorectal epithelium in order to test alternative contrast agents and the viability of computer-aided quantification in various optical imaging modalities aimed at cancer detection. Cancer diagnosis, surveillance, and treatment can benefit from systems

designed to reduce invasiveness, turn-around time, and interobserver variability, as well as increase detection at early stages and therefore increase survival rates.

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Chapter VII: Appendix