2. Propuesta de diseño arquitectónico para el GDA eXcriba 29
2.1.2. Aspectos generales de la arquitectura
Figure 4-50. 1H NMR (400 MHz, CDCl3, 25 °C) spectrum of 6 subjected to increasing amounts of TFA. Each plot represents the addition of 20 µL of a 10% TFA solution in CDCl3 to 500 µL of
a 0.023 M solution of 6
155
Figure 4-51. 1H NMR (400 MHz, CDCl3, 25 °C) spectrum of 6 subjected to increasing amounts of TFA. Each plot represents the amount of a 10% TFA solution in CDCl3 to 500 µL of a 0.023 M
solution of 6
156 4.3.6 Additional details to the ALIE Computations
Figure 4-52. ALIEs of the mono and diprotonated 15: while for the monoprotonated form 15·H+ a clear preference for a chlorination at the 10-position is to be expected, diprotonated 15 H2+
does not show any preference for the 10 or 15 position. Here an increased energy range of 0.8 eV is shown to emphasize the differences in the meso-positions of the compounds
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