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Patrycja Nowak‑Sliwinska1,2 · Kari Alitalo3 · Elizabeth Allen4 · Andrey Anisimov3 · Alfred C. Aplin5 ·

Robert Auerbach6 · Hellmut G. Augustin7,8,9 · David O. Bates10 · Judy R. van Beijnum11 · R. Hugh F. Bender12 ·

Gabriele Bergers13,4 · Andreas Bikfalvi14 · Joyce Bischoff15 · Barbara C. Böck7,8,9 · Peter C. Brooks16 ·

Federico Bussolino17,18 · Bertan Cakir19 · Peter Carmeliet20,21 · Daniel Castranova22 · Anca M. Cimpean23 ·

Ondine Cleaver24 · George Coukos25 · George E. Davis26 · Michele De Palma27 · Anna Dimberg28 ·

Ruud P. M. Dings29 · Valentin Djonov30 · Andrew C. Dudley31,32 · Neil P. Dufton33 · Sarah‑Maria Fendt34,35 ·

Napoleone Ferrara36 · Marcus Fruttiger37 · Dai Fukumura38 · Bart Ghesquière39,40 · Yan Gong19 ·

Robert J. Griffin29 · Adrian L. Harris41 · Christopher C. W. Hughes12 · Nan W. Hultgren12 · M. Luisa Iruela‑Arispe42 ·

Melita Irving25 · Rakesh K. Jain38 · Raghu Kalluri43 · Joanna Kalucka20,21 · Robert S. Kerbel44 · Jan Kitajewski45 ·

Ingeborg Klaassen46 · Hynda K. Kleinmann47 · Pieter Koolwijk48 · Elisabeth Kuczynski44 · Brenda R. Kwak49 ·

Koen Marien50 · Juan M. Melero‑Martin51 · Lance L. Munn38 · Roberto F. Nicosia5,52 · Agnes Noel53 · Jussi Nurro54 ·

Anna‑Karin Olsson55 · Tatiana V. Petrova56 · Kristian Pietras57 · Roberto Pili58 · Jeffrey W. Pollard59 · Mark J. Post60 ·

Paul H. A. Quax61 · Gabriel A. Rabinovich62 · Marius Raica23 · Anna M. Randi33 · Domenico Ribatti63,64 ·

Curzio Ruegg65 · Reinier O. Schlingemann46,48 · Stefan Schulte‑Merker66 · Lois E. H. Smith19 · Jonathan W. Song67,68 ·

Steven A. Stacker69 · Jimmy Stalin66 · Amber N. Stratman22 · Maureen Van de Velde53 · Victor W. M. van Hinsbergh48 ·

Peter B. Vermeulen50,72 · Johannes Waltenberger70 · Brant M. Weinstein22 · Hong Xin36 · Bahar Yetkin‑Arik46 ·

Seppo Yla‑Herttuala54 · Mervin C. Yoder71 · Arjan W. Griffioen11 1 Molecular Pharmacology Group, School of Pharmaceutical

Sciences, Faculty of Sciences, University of Geneva, University of Lausanne, Rue Michel-Servet 1, CMU, 1211 Geneva 4, Switzerland

2 Translational Research Center in Oncohaematology,

University of Geneva, Geneva, Switzerland

3 Wihuri Research Institute and Translational Cancer Biology

Program, University of Helsinki, Helsinki, Finland

4 Laboratory of Tumor Microenvironment and Therapeutic

Resistance, Department of Oncology, VIB-Center for Cancer Biology, KU Leuven, Louvain, Belgium

5 Department of Pathology, University of Washington, Seattle,

WA, USA

6 University of Wisconsin, Madison, WI, USA 7 European Center for Angioscience, Medical Faculty

Mannheim, Heidelberg University, Heidelberg, Germany

8 Division of Vascular Oncology and Metastasis Research,

German Cancer Research Center, Heidelberg, Germany

9 German Cancer Consortium, Heidelberg, Germany 10 Division of Cancer and Stem Cells, School of Medicine,

University of Nottingham, Nottingham, UK

11 Angiogenesis Laboratory, Department of Medical Oncology,

VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands

12 Department of Molecular Biology and Biochemistry,

University of California, Irvine, CA, USA

13 Department of Neurological Surgery, Brain Tumor Research

Center, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA

14 Angiogenesis and Tumor Microenvironment Laboratory

15 Vascular Biology Program and Department of Surgery,

Harvard Medical School, Boston Children’s Hospital, Boston, MA, USA

16 Center for Molecular Medicine, Maine Medical Center

Research Institute, Scarborough, ME, USA

17 Department of Oncology, University of Torino, Turin, Italy 18 Candiolo Cancer Institute-FPO-IRCCS, 10060 Candiolo,

Italy

19 Department of Ophthalmology, Harvard Medical School,

Boston Children’s Hospital, Boston, MA, USA

20 Laboratory of Angiogenesis and Vascular Metabolism,

Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium

21 Laboratory of Angiogenesis and Vascular Metabolism,

Center for Cancer Biology, VIB, Leuven, Belgium

22 Division of Developmental Biology, Eunice Kennedy Shriver

National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA

23 Department of Microscopic Morphology/Histology,

Angiogenesis Research Center, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania

24 Department of Molecular Biology, Center for Regenerative

Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA

25 Ludwig Institute for Cancer Research, Department

of Oncology, University of Lausanne, Lausanne, Switzerland

26 Department of Medical Pharmacology and Physiology,

University of Missouri, School of Medicine and Dalton Cardiovascular Center, Columbia, MO, USA

27 School of Life Sciences, Swiss Federal Institute

of Technology, Lausanne, Switzerland

28 Department of Immunology, Genetics and Pathology,

Uppsala University, Uppsala, Sweden

29 Department of Radiation Oncology, University of Arkansas

for Medical Sciences, Little Rock, AR, USA

30 Institute of Anatomy, University of Bern, Bern, Switzerland 31 Department of Microbiology, Immunology, and Cancer

Biology, University of Virginia, Charlottesville, VA, USA

32 Emily Couric Cancer Center, The University of Virginia,

Charlottesville, VA, USA

33 Vascular Sciences, Imperial Centre for Translational

and Experimental Medicine, National Heart and Lung Institute, Imperial College London, London, UK

34 Laboratory of Cellular Metabolism and Metabolic

Regulation, VIB Center for Cancer Biology, Leuven, Belgium

35 Laboratory of Cellular Metabolism and Metabolic

Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute, Leuven, Belgium

36 University of California, San Diego, La Jolla, CA, USA 37 Institute of Ophthalmology, University College London,

London, UK

38 Edwin L. Steele Laboratories, Department of Radiation

Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

39 Metabolomics Expertise Center, VIB Center for Cancer

Biology, VIB, Leuven, Belgium

40 Department of Oncology, Metabolomics Expertise Center,

KU Leuven, Leuven, Belgium

41 Molecular Oncology Laboratories, Oxford University

Department of Oncology, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK

42 MCDB, University of California, Los Angeles, CA, USA 43 Department of Cancer Biology, Metastasis Research Center,

The University of Texas MD Anderson Cancer Center, Houston, TX, USA

44 Department of Medical Biophysics, Biological Sciences

Platform, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada

45 Department of Physiology and Biophysics, University

of Illinois, Chicago, IL, USA

46 Ocular Angiogenesis Group, Departments of Ophthalmology

and Medical Biology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

47 The George Washington University School of Medicine,

Washington, DC, USA

48 Department of Ophthalmology, University of Lausanne,

Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland

49 Department of Pathology and Immunology, University

of Geneva, Geneva, Switzerland

50 HistoGeneX, Antwerp, Belgium

51 Department of Cardiac Surgery, Harvard Medical School,

Boston Children’s Hospital, Boston, MA, USA

52 Pathology and Laboratory Medicine Service, VA Puget

Sound Health Care System, Seattle, WA, USA

53 Laboratory of Tumor and Developmental Biology,

GIGA-Cancer, University of Liège, Liège, Belgium

54 Department of Biotechnology and Molecular Medicine,

University of Eastern Finland, Kuopio, Finland

55 Department of Medical Biochemistry and Microbiology,

Science for Life Laboratory, Uppsala Biomedical Center, Uppsala University, Uppsala, Sweden

56 Department of oncology UNIL-CHUV, Ludwig Institute

for Cancer Research Lausanne, Lausanne, Switzerland

57 Division of Translational Cancer Research, Department

of Laboratory Medicine, Lund, Sweden

58 Genitourinary Program, Indiana University-Simon Cancer

Center, Indianapolis, IN, USA

59 Medical Research Council Centre for Reproductive Health,

College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK

60 Department of Physiology, Maastricht University, Maastricht,

The Netherlands

61 Einthoven Laboratory for Experimental Vascular Medicine,

62 Laboratory of Immunopathology, Institute of Biology

and Experimental Medicine, National Council of Scientific and Technical Investigations (CONICET), Buenos Aires, Argentina

63 Department of Basic Medical Sciences, Neurosciences

and Sensory Organs, University of Bari Medical School, Bari, Italy

64 National Cancer Institute “Giovanni Paolo II”, Bari, Italy 65 Department of Oncology, Microbiology and Immunology,

Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland

66 Institute of Cardiovascular Organogenesis and Regeneration,

Faculty of Medicine, WWU , Münster, Germany

67 Department of Mechanical and Aerospace Engineering, The

Ohio State University, Columbus, OH, USA

68 Comprehensive Cancer Center, The Ohio State University,

Columbus, OH, USA

69 Tumour Angiogenesis and Microenvironment Program, Peter

MacCallum Cancer Centre and The Sir Peter MacCallum, Department of Oncology, University of Melbourne, Melbourne, VIC, Australia

70 Medical Faculty, University of Münster,

Albert-Schweitzer-Campus 1, Münster, Germany

71 Department of Pediatrics, Indiana University School

of Medicine, Indianapolis, IN, USA

72 Translational Cancer Research Unit, GZA Hospitals,

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