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Desarrollo sostenible y entorno natural e Rnesto R uiz

Valorisation & Spin-off Activities

In June 2014, on the occasion of the CERN60 event in Amsterdam, an agreement was signed between CERN director Rolf Heuer and Nikhef director Frank Linde, on the establishment of a CERN Business Incubation Center at Nikhef. This Nikhef-CERN BIC, aimed at helping entrepreneurs to develop and bring to the market technologies emerging from subatomic physics, is located adjacent to Nikhef. In the Nikhef-CERN BIC, these entrepreneurs can make use of CERN and Nikhef facilities and of the services of the Nikhef- CERN BIC partners: P2IP B.V., Amsterdam Venture Lab and the Innovation Exchange Amsterdam (the collaboration of Technology Transfer Offices of the two universities in Amsterdam and their two academic medical centers). Nikhef’s detector R&D activities around the Medipix and Timepix family of chips (with our emphasis on ASIC develop- ment and readout expertise) continue to be a fruitful basis for valorisation and cooperation with industry; we point to the longtime collaboration with Panalytical and the establishment of spin-off company Amsterdam Scientific Instruments (ASI, further described below). Another example is the EC sponsored Initial Training Network ‘INFIERI’, in which Nikhef, together with Philips, investigates new architectures for front-end cir- cuitry used in edge-on illumination. A second goal is to develop high-speed optical data links for fast electronics in radiation en- vironments. The focus is on data serialisation and transmission, aimed not only at high-energy physics detectors but also with an application perspective towards medical imaging, such as this edge-on illumination.

The Medipix activities are also central in the ERC Proof of Concept project, acquired by André Mischke, but then focused on its application in mammography in which edge-on illumina- tion is also applied. Within this project we are also collaborating with Philips and ASI.

Finally, in 2014 a PhD thesis was finished by Enrico Schioppa fo- cusing on spectral X-ray computed tomography. The focus of the thesis was the incorporation of the energy information in the it- erative reconstruction algorithm. This work will continue in both the edge-on illumination project and the mammography project. Also the gravitational waves (GW) detection programme has an impressive valorisation potential. The ‘Tremornet’-project, a col- laboration between Shell and Nikhef/VU on the development of (wireless) seismic sensor nodes, with Nikhef’s spin-off company Innoseis as subcontracted party, was completed successfully in early 2014, with all deliverables accepted by Shell. This pro- ject generated a modest ‘TKI-allowance’ (TKI = Top consortia

for Knowledge and Innovation, an instrument in the industrial topsector policy of the Dutch government), which will be used in a follow-up project with Shell and Innoseis, entailing the pilot deployment of seismic nodes at a large industrial scale.

In the context of the GW activity a (European) patent application titled “MEMS sensor structure comprising mechanically loaded sus- pension springs” was filed in 2014, jointly with VU University. With regard to Nikhef’s cooling expertise, in 2014, Nikhef car- ried out a small engineering project for ASML. Other work for ASML, acquired in 2012, was completed in early 2014. Finally, Nikhef’s datacenter activities (in particular for custom- ers of the Amsterdam Internet Exchange, AMS-IX) have further increased. Likewise, our position as provider in the national e- infrastructure, coordinated by SURF, has been consolidated. Start-ups

As with most start-ups every year brings its challenges and op- portunities, 2014 has been a turbulent, yet exciting, year for ASI and Omics2image. There have been many changes and new in- sights that drive a clearer focus on the company’s vision, path and value to customers. The company is convinced that its technol- ogy platform for the next generation radiation cameras will yield the biggest impact in the field of Life Sciences. The implementa- tion in the area of Mass Spectrometry and Electron Microscopy has shown some great results that have triggered interest from around the globe. The holding company ASIH has secured fund- ing with a group of informal investors. Other local and interna- tional opportunities for funding with institutional investors are

Figure 1. CERN Director General Rolf Heuer and Nikhef director Frank Linde sign the contract for the CERN Business Incubation Center at Nikhef.

being explored. The goal is to complete this funding early 2015. In the last six months, the focus has been on expanding sales channels and opportunities beyond the scientific market. ASI has agreements in place with a number of resellers in China, Japan, Russia and India. The company is also looking at establishing OEM (Original Equipment Manufacturer) relationships with multinational scientific equipment companies. Also in 2014, the company has entered into several collaborative projects: a Eureka/Eurostars project has been granted to a consortium with a Spanish partner and in the NWO funding scheme ‘New Chemical Innovations /Technology Area’ a project was awarded to a consortium together with Leiden University and the new research institute M4I at Maastricht University.

Finally, the team is growing again! The company was joined by four new team members, who will seek to employ its cutting-edge detection technology in further innovative applications.

Sensiflex, Nikhef’s startup aimed at selling the Rasnik align- ment system in non-scientific domains had another quiet year with a moderate turnover. Attempts to attract a new CEO have not yet succeeded.

Innoseis, established mid 2013, aims to commercialise technolo- gies arising from Nikhef’s gravitational waves program. In the previous year Innoseis has focussed on further developing its ultra-low power wireless seismic sensing system for applications in the Oil & Gas industry. This technology allows companies to make more efficient use of their existing hydrocarbon resources. Innoseis was present at two major conferences during 2014 and received a lot of interest from potential users around the globe.

1&12 IP Nikhef/AMOLF FOM P2IP BV Sensiflex BV Omics2Image BV ASI Holding ASI BV ‘Stichting Administratiekantoor’ Sensiflex ‘Stichting Administratiekantoor’ ASI Holding

Certificate holders Certificate holders

Holding BVs – other shareholders

Figure 2. The current legal structure around Nikhef’s start-ups.

A large-scale industrial pilot conducted together with Shell is planned for the second half of 2015. Innoseis has also received orders for its vibration isolation systems, including a project to reduce vibrations in a high-precision cryogenic experiment in the Netherlands. Like the previous year, 2015 will be a very exciting and challenging year for Innoseis and will see its team and client base grow.

At the end of 2014, NoZAP, the startup aimed at developing live streaming television on demand, has decided to stop its activi- ties, after one and a half years of operations, due to the unclear business perspective.

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Annual Report 2014 Nikhef