Perform a careful physical examination, if possible with anthropometric and body composition testing as described below (Table 1). Compare current findings with past assessments and review at least every 6 months.
The physical examination should include the following:
• Vital signs, with orthostatic vital signs if dehydration is suspected
• Weight (compare with previous values) and body mass index (BMI)
• General appearance and gross nutritional status (e.g., obesity, cachexia, wasting) • Body habitus: loss of subcutaneous fat in face, buttocks, arms and legs and/or
increased fat in abdomen, breasts, neck, and upper back (“buffalo hump”)
• Muscle mass
• Mouth: breakdown in oral mucosa, cheilosis, angular stomatitis, glossitis, papillar atrophy • Abdomen: hepatomegaly (may be caused by
fatty infiltration)
• Skin: dryness, peeling, breakdown, pallor, hypopigmentation or hyperpigmentation • Nails: pale nail beds, fissures or ridges • Neurologic system, including strength,
sensation, coordination, gait, deep tendon reflexes
Anthropometric and body composition tests are usually performed by registered dietitians.
They can provide important information about patients’ nutritional status.
Sec tion 3: Health M aint enance and Disease P re vention
Table 1. Anthropometric Measurements for Adults and Children
Height Weight Assessment for Changes over Time
Adults Measure at
baseline (self- report is not accurate).
• Measure at least quarterly and consider intervention when small changes are observed. Do not wait until major amounts of weight have been lost or gained.
• Record sequentially at the front of the patient’s chart and monitor for trends.
Use healthy, premorbid weight to assess change, not the first clinic weight or the ideal weight. (Use the patient’s weight at a time when the patient is healthy, feels well, and can easily maintain that weight.)*
Children Measure at least quarterly using length board (0-2 years) or wall-mounted stadiometer (≥2 years).
• Measure at least quarterly and consider intervention when small changes are observed. Do not wait until the patient has dropped significantly on the growth chart.
• Calculate age and plot the measurements on growth charts specific for age, sex, and country.#
Assessment of optimal growth is based on the observed pattern over time. General goals include a weight relatively “matched” for length or height (about the same percentile) and relative stability of percentile tracking over time.* #
* BMI (body mass index) is useful as an evaluative index. See chapter Initial Physical Examination, and the U.S. Centers for Disease Control and Prevention (CDC) online calculator at www.cdc.gov/healthyweight/assessing/bmi. Accessed December 1, 2013. # Growth charts for children in the United States are available online from the CDC at www.cdc.gov/growthcharts. A variety of growth
charts are available for children from specific ethnic groups (e.g., Chinese, Vietnamese, Thai), children with selected conditions affecting growth (e.g., Down syndrome), or those who are born prematurely. Percentiles for both height and weight should be recorded sequentially.
Body Composition Testing
Body composition commonly is tested by bioelectrical impedance analysis (BIA) (Table 2) or skinfold thickness and circumference (Table 3).
Table 2. Bioelectrical Impedance Analysis
BIA testing is the standard of care for adults but has not been well validated for children:
• BIA is useful for assessing disease progression or health maintenance, documenting response to treatment, and justifying the cost of nutritional supplements and AIDS-wasting medications.
• The test is simple, noninvasive, and quick (<5 minutes). However, staff training and specialized software are required to interpret the results.
• Perform BIA at baseline, if possible. Update every 6-12 months or more frequently if the patient is ill, has a decline in immune status, or has a weight change of 5-10%.
• The BIA test reports the following:
• Body cell mass (BCM): the target component, reflecting cells in muscles, organs, and the circulation; losses may indicate AIDS wasting. BCM is recorded in pounds. Monitor for trends.
• Fat: an index of energy stores; recorded in pounds and percentage.
• Phase angle: a measure of cellular integrity, an independent indicator of morbidity and mortality in HIV-infected patients.
Sec tion 3: Health M aint enance and Disease P re vention
Table 3. Skinfold Thickness and Circumference Measures
Skinfold thickness and circumference measures can be used for adults and children in resource-limited settings, and for situations in which bioelectrical impedance analysis is not available. Circumference measures also can be used to monitor changes over time associated with lipodystrophy in adults.
• Skinfold thickness is measured with calipers.
• Circumference measures are taken at specific anatomical landmarks with nonstretchable tape. • Techniques and protocols for taking anthropometric measurements can be found at the CDC website
(www.cdc.gov/nchs/data/nhanes/nhanes_03_04/BM.pdf). Laboratory Testing
Perform basic laboratory (blood) tests, including the following:
• Hemoglobin and/or hematocrit • Total protein, albumin
• Fasting blood glucose
• Fasting lipids (triglycerides, total cholesterol, low-density lipoprotein cholesterol [LDL], high-density lipoprotein cholesterol [HDL]) • CD4 cell count and HIV viral load, if no
recent values are available
• Specific vitamin and nutrient tests as indicated by symptoms (e.g., iron studies in case of anemia, vitamin B12 in case of peripheral neuropathy)
• Others tests, such as testosterone and thyroid hormone levels as appropriate, to rule out other causes of symptoms
A: Assessment
Assess subjective information and objective
findings to evaluate nutritional status. Identify Nutrition Concerns Several factors may influence nutrition, including the following:
• Barriers to good nutrition (e.g., lack of knowledge or motivation for self-care, poor appetite, lack of money for food, lack of facilities for food storage and preparation) • Lifestyle factors (e.g., smoking, substance
abuse, frequent eating out, erratic eating patterns, hectic schedule, high stress)
• Physical problems affecting food and nutrient intake (e.g., poor appetite, nausea, fatigue, pain, weakness, mouth or throat pain, acid reflux, missing or decayed teeth, poorly fitting dentures, poor eyesight, constipation)
• Nutrient losses (e.g., owing to diarrhea, vomiting)
• Potential confounding factors (e.g., use of multiple overlapping or questionable supplements, eating disorders)
Evaluate Dietary Intake
Assess the following diet-related issues: • Expected excesses or deficiencies from
dietary history or interview
• Rating of food security, including access to cooking and refrigeration
• Food intolerances, aversions, or allergies likely to affect adequacy of intake • Special needs related to other conditions
(e.g., documented cardiovascular disease, diabetes, hypertension)
Evaluate Weight, Body Composition, and Weight Distribution
Assess physical findings of malnutrition and confirm with nutrition history, laboratory tests, and anthropometric evidence. Normal and abnormal findings of anthropometric tests and recommendations for monitoring changes over time are presented in Table 4.
Sec tion 3: Health M aint enance and Disease P re vention
Table 4. Evaluating the Findings of Anthropometric Tests
Monitoring Trends and Recommendations Adults
• Chart trends over time relative to previous measurements and the following population norms:
• BMI (healthy range: 19-25) • BIA:
• BCM (percentage of weight): women 30-35%; men 40-45% • Fat (percentage of weight): women 20-30%; men 15-25% • Phase angle: women >5; men >6
• Skinfold thicknesses and circumferences: Chart changes in absolute measures and percentiles
• Changes in body contours: Evaluate lipodystrophy (excess accumulation of fat in abdomen, breasts, dorsocervical area) and lipoatrophy (loss of subcutaneous fat in face, extremities, buttocks)
Children
• Plot measurements on growth charts and track percentiles over time (the consistency of percentiles rather than the absolute percentile is important) • Skinfold thicknesses and circumferences: Chart changes in absolute measures and percentiles Abbreviations: BCM = body cell mass; BIA = bioelectrical impedance analysis; BMI = body mass indexx