El Concepto De Justicia

The results of this study showed the importance of investigating brain damage and cortical disconnection in motor network in chronic stroke. Cortical disconnection is a complementary factor to brain lesion that contributes to the severity of motor impairments and impacts the recovery after stroke. Understanding the mechanisms of brain reorganization and structural alteration after stroke can provide more insight into post-stroke recovery and plasticity. The next step is to develop a prognostic method that can examine and predict post-

stroke recovery. This will assist with the identification of patients with greater potential for recovery and with selecting the best appropriate interventions for individual patient based on their structural brain connectome and damage. Future research should also include the application of innovative treatments such as transcranial magnetic stimulation to examine the training-induced neural plasticity and potential changes in functional and structural connectivity for better target therapeutic interventions to increase post stroke motor recovery.

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APPENDIXA-TABLESOFLESIONSYMPTOMMAPPINGRESULTS

Significant results of correlational analysis of cortical damage and behavioral measurements are showed in these two tables. Numbers in the tables represent the Fisher z-scores. Threshold z-score of 2.144 was considered as significant.

Table A.1 Lesion symptom mapping results of behavioral measurements

Behavioral Measurements ROI 15 ROI 17 ROI 25 ROI 27 ROI 53 ROI 57 ROI 61 ROI 65 ROI 67 ROI 73 ROI 75 ROI 79 ROI 81 ROI 83 ROI 85 Target Hits 0.00 0.59 0.00 0.00 1.13 1.75 0.00 2.281* 2.745* 2.463* 2.328* 1.62 1.61 2.277* 2.11 Hand Bias Speed 0.00 0.45 0.10 0.23 1.22 0.34 0.00 1.80 1.89 1.66 1.71 0.06 0.59 0.57 0.28 Miss Bias 0.00 0.00 0.87 0.31 0.00 0.00 0.00 0.13 0.62 0.86 0.72 1.53 1.22 1.15 1.12 Behavioral Measurements ROI 109 ROI 111 ROI 113 ROI 115 ROI 223 ROI 225 ROI 273 ROI 275 ROI 277 ROI 279 ROI 287 ROI 291 ROI 293 ROI 295 ROI 297 Target Hits 1.57 1.48 2.07 1.26 0.00 0.00 2.205 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 Hand Bias Speed 1.09 0.77 1.10 1.10 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 Miss Bias 1.53 2.29* 2.09 2.503* 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00

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APPENDIXB-TABLESOFCONNECTOME-BASEDLESIONSYMPTOMMAPPINGRESULTS

Significant results of correlational analysis of cortical disconnection and task performance are showed in the table. (Threshold z-score =2.14)

Table B.1 Connectome-Based Lesion symptom mapping results of task performance

ROIs Connectivity Z- score ROIs Connectivity Z- score ROIs Connectivity Z- score ROIs Connectivity Z- score ROIs Connectivity Z- score 15-57 2.53 27-75 2.41 81-83 1.8623 111-81 2.4576 225-27 1.813 15-65 2.18 53-73 2.33 75-85 2.1031 113-53 1.7554 225-57 2.239 15-67 2.22 53-75 2.27 109-53 2.123 113-61 2.1005 225-65 1.69 15-73 2.83 57-65 2.63 109-61 2.4713 113-75 1.8904 225-67 2.815 15-75 2.26 57-67 2.27 109-75 2.6912 113-79 1.7821 225-73 2.733 15-81 2.38 57-73 2.69 109-81 1.6552 113-81 2.0049 225-79 1.658 17-53 2.19 57-75 2.92 111-53 2.9567 115-79 1.874 225-83 1.845 17-61 2.20 61-67 2.59 111-61 3.7746 223-27 2.2196 225-111 1.771 17-75 2.18 61-73 3.64 111-65 2.4817 223-67 1.8644 225-115 1.876 17-79 2.43 61-75 3.27 111-67 2.3148 223-79 1.8785 273-57 2.512 25-73 2.32 65-75 3.09 111-73 2.8542 223-81 2.5865 273-83 2.052 27-61 2.49 67-75 3.14 111-75 3.5645 223-113 1.8979 273-111 2.011 27-65 2.15 57-81 1.714 111-79 2.5568 223-115 2.1885 273-287 2.17

Significant results of correlational analysis of cortical disconnection and motor impairment are showed in this table. (Threshold z-score =2.144)

Table B.2 Connectome-Based Lesion symptom mapping results of motor impairment

ROIs Connectivity Z-score ROIs Connectivity Z-score ROIs Connectivity Z-score 27-25 2.44 75-27 2.35 109-75 2.55 65-15 2.59 75-53 2.56 111-53 2.30 65-17 2.16 75-57 2.37 111-75 2.37 65-25 2.45 75-61 2.45 111-81 2.33 65-57 2.84 75-67 2.69 223-75 2.29 67-57 2.26 75-85 2.23 223-115 2.31 73-15 2.93 109-53 2.67 225-67 2.37 73-25 2.18 109-61 2.72 225-73 2.50 73-57 2.76 109-67 2.28 277-75 3.15 75-15 2.74 109-73 2.59 295-115 2.51 75-17 2.18

Significant results of correlational analysis of cortical disconnection and visuospatial impairment are showed in this table. (Threshold z-score =2.144)

Table B.3 Connectome-Based Lesion symptom mapping results of visuospatial impairment

ROIs Connectivity Z-score ROIs Connectivity Z-score 79-27 2.22 279-81 2.61 81-17 2.32 279-113 2.40 81-53 2.15 287-81 2.46 81-61 2.25 287-111 2.33 81-67 2.24 287-113 3.40 83-75 2.78 293-83 2.19 115-111 3.38 293-111 2.78 223-81 2.21 293-113 3.46 223-83 2.31 293-115 2.26