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2. RELACIÓN ESTRUCTURA-FUNCIÓN DE LA

2.1. Importancia de la secuencia aminoacídica de la región C-

2.1.2. Papel de los aminoácidos del motivo “CAAX” en la

For notational convenience we omit dependency on time and write x(t) simply as x.

tional to adopt Technology i, given the current adoption levels, x. To determine the

fraction of adopters of each technology, we introduce the notion ofindifference points,

which identify thresholds in users technology valuation (θ)corresponding to changes

in technology preference. Specifically, θ0i(x),i∈ {1,2}identify theθvalue separating

users with a negative utility for Technologyifrom those with a positive utility. In other words, for technology penetration levelsx,θ0i(x)is such thatUi(θ0i,x) =0, andUi(θ,x)

is positive (negative) forθvalues larger (smaller) thanθ0i.

From eqs. (3.1) and (3.2),Ui(θ0i,x) =0 gives

θ01(x) = p1−(x1+α1βx2)

q1

(3.5)

θ02(x) = p2−(βx2+α2x1)

q2 (3.6)

Similarly, θ12(x) corresponds to the θ value separating users preferring Technology 1

from those preferring Technology 2,i.e., U1(θ12,x) =U2(θ12,x)and users withθ>θ12(x)

derive greater utility from Technology 2 than Technology 1 (recall that q2>q1). Set- ting,U1(θ12,x) =U2(θ12,x)gives

θ12(x) = (1−α2)x1−β(1−α1)x2+p2−p1

q2q1 (3.7)

Combining eqs. (3.5)-(3.7) gives

θ12(x)−θ01(x) = q2 q2−q1 (θ02(x)−θ01(x)), (3.8) θ12(x)−θ02(x) = q1 q2q1(θ 0 2(x)−θ01(x)), (3.9)

Proposition 4

Ifθ01(x)<θ02(x), thenθ12(x)>θ02(x)>θ01(x).

Ifθ01(x)≥θ02(x), thenθ12(x)≤θ02(x)≤θ01(x).

Proposition 4 constrains the possible orderings of the indifference points given by eqs. (3.5)-(3.7), so thatHi(x),i∈ {1,2}can be characterized in a compact manner.

H1(x) =        [θ12(x)][0,1]−[θ01(x)][0,1] ifθ01(x)<θ 0 2(x) 0 otherwise (3.10) H2(x) =        1[θ12(x)][0,1] ifθ01(x)<θ02(x) 1[θ02(x)][0,1] otherwise

wherey[a,b]is the ‘projection15’ ofyinto[a,b].

The expressions forH1(x)andH2(x)determine the trajectory as well as the equilib- rium outcome of the adoption process as per eqs. (3.3) and (3.4) respectively. Eq. (3.10) characterizes Hi(x), i={1,2} through multiple possible expressions that depend on the relative ordering ofθ01(x),θ02(x)andθ12(x), and the outcome of their projections on

[0,1]. Identifying the different combinations that eq. (3.10) gives rise to calls for par- titioning the (x1,x2)-plane intoregions, each corresponding to unique expressions for

the(H1(x),H2(x))pair. A method for constructing such a partition is described next. First, consider all values of x which satisfy θ01(x)θ02(x). In the corresponding half-plane of the(x1,x2)-plane, H1(x) is always 0, but the value ofH2(x)depends on the projection of θ02(x)on[0,1](i.e.,whetherθ02(x)≤0,0<θ02(x)<1,or 1≤θ02(x)).

This creates three regions in the(x1,x2)-plane, each with a different expression for the 15i.e.,its value isyfory[a,b],afory<a, andbfory>b.

(H1(x),H2(x))pair. These three regions, labeledR1,R2andR3, and the corresponding conditions onθ02(x)appear in the left side of Table 3.1. The expressions forHi(x), i=

{1,2}in each region are provided in Table 3.2.

Conversely, for values of x which satisfy θ01(x) < θ02(x) (the other half-plane),

eq. (3.10) indicates that expressions for H1(x) and H2(x) depend on the positions of both θ12(x) and θ01(x) relative to 0 and 1 (i.e., whether θ12(x) ≤0, 0<θ12(x) <1 or

1θ12(x), and similarly forθ01(x)). This yields nine possible combinations. The num-

ber of feasible combinations can, however, be reduced to six using Proposition 4, which constrains θ01(x)<θ02(x)<θ12(x). For example, when θ01(x)<θ02(x), θ12(x)0 and 1θ01(x) is infeasible per Proposition 4. Thus in the half-plane θ01(x)<θ02(x), there

are six possible expressions for Hi(x), i={1,2}. These expressions are reported on the right side of Table 3.1, with the corresponding regions labeledR4toR9. Combining

the two half-planes gives a total of nine regions, R1 to R9, where in each region the

(H1(x),H2(x))pair has a unique expression as specified in Table 3.2.

This partitioning in nine regions has a graphical representation, as shown in Fig- ure 3.1. The lineθ01(x) =θ02(x)splits the(x1,x2)-plane in the two previously mentioned

half-planes. The two lines corresponding to θ02(x) =0 andθ02(x) =1 are parallel, and

define the three regions R1, R2 and R3 in the half-planeθ10(x)≥θ02(x). Similarly, the

linesθ01(x) =0,θ01(x) =1,θ12(x) =0 andθ12=1, divide the second half-plane into the

six regions,R4toR9. Figure 3.1 also illustrates that the lines θ02(x) =0,θ01(x) =0 and θ12(x) =0 always intersect at a point denoted asP, and the linesθ02(x) =1,θ01(x) =1

and θ12(x) =1 always intersect at a point denoted asQ, with bothP andQ16 lying on

the line θ01 =θ02. The points P and Q can be shown to act as “anchors” that ensure

that the(x1,x2)-plane is always partitioned into exactly nine regions with fixed relative

positions.

It should also be noted that all nine regions need not always be feasible. Whether or not they are feasible depends on their relative position in the solution space,

S={(x1,x2)s.t.0≤x1≤1,0≤x2≤1,x1+x2 ≤1}. The number of regions that lie

insideS(and hence are relevant to the analysis) is a function of the system parameters

(qi,pi,β,αi;i={1,2}). Last but not least, as shown in Appendix B.1, the partitioning

of the solution space into nine regions actually holds for more generic (monotonic) ex- ternality functions,i.e.,it is not an artifact of the simplified linear externality function.

Finally, we pause to briefly interpret the conditions that define each region, and their

implications for solutions. We do so by way of an example, focusing on Region R8.

Region R8 is defined as the set of adoption levels, x= (x1,x2), for which 1≤θ12(x)

and 0θ01(x)<1. The condition 1≤θ12(x) implies that in Region 8 all users prefer

Technology 1 over 2. Hence any existing Technology 2 adopter will disadopt. Thus, in

R8, users can either be non-adopters of both technologies (0<θ<θ01(x)) or adopters

of Technology 1 (ifθ>θ01(x)). Similar interpretations are possible for other regions. 16The coordinates of the points PandQcan be readily found by solving simple systems of linear equations given by eqs.(3.5)-(3.7).

Figure 3.1: Region Partitions

Table 3.1: Partitions characterizingHi(x) θ01(x)≥θ02(x) θ01(x)<θ02(x)

Region condition Region condition

R1 θ02(x)0 R4 θ12(x)0, 0θ01(x) R2 0<θ02(x)<1 R5 0<θ12(x)<1, θ01(x)≤0 R3 1≤θ02(x) R6 0<θ21(x)<1, 0<θ01(x)<1 R7 1θ12(x), θ01(x)0 R8 1θ12(x), 0<θ01(x)<1 R9 1θ12(x), 1θ01(x)

Table 3.2: Expressions forHi(x) R1 H1(x) =0 H2(x) =1 R2 H2(x) =1−p2−(βxq22+α2x1) R3 H2(x) =0 R4 H1(x) =0 H2(x) =1 R5 H1(x) =(1−α2)x1−β(1−α1)x2+p2−p1 q2−q1 H2(x) =1− (1−α2)x1−β(1−α1)x2+p2−p1 q2−q1 R6 H1(x) =(1−α2)x1−βq(12−−qα11)x2+p2−p1 H2(x) =1− (1−α2)x1−β(1−α1)x2+p2−p1 q2−q1 −p1−(x1+βα1x2) q1 R7 H1(x) =1 H2(x) =0 R8 H1(x) =1−p1−(x1+βα1x2) q1 R9 H1(x) =0