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Paper de l’enzim PFK-2/FBPasa-2 en el metabolisme de les

2. El paper de la reprogramació metabòlica de les

3.1 Paper de l’enzim PFK-2/FBPasa-2 en el metabolisme de les

The Company has $625.0 million in outstanding Notes. See Note 5. The Notes are guaranteed by all of the Company's 100% owned domestic subsidiaries (the "Subsidiary Guarantors") and are collateralized by the assets of all of the Company's 100% owned subsidiaries. The Notes are fully and unconditionally guaranteed on a joint and several basis by each guarantor subsidiary and the Company. There are no contractual restrictions limiting cash transfers from guarantor subsidiaries by dividends, loans or advances to the Company. The Notes are not guaranteed by the Company's foreign subsidiaries (the “Non-Guarantor Subsidiaries”).

The following tables present condensed consolidating financial statements for the parent company, the Subsidiary Guarantors and the Non-Guarantor Subsidiaries, respectively, for 2011, 2012, and 2013. The consolidating financial information below follows the same accounting policies as described in the Consolidated Financial Statements, except for the use of the equity method of accounting to reflect ownership interests in wholly-owned subsidiaries, which are eliminated upon consolidation.

Subsequent to the issuance of the Company’s consolidated financial statements for the years ended December 25, 2011 and December 30, 2012, the Company reclassified Investment in affiliated companies to a separate line item in its Condensed Consolidating Statement of Cash Flows. These amounts were previously combined with financings from affiliated companies.

F- 46

Quarter First Quarter Second Quarter Third Quarter Fourth

Fiscal year 2013

Revenues $ 253.3 $ 235.2 $ 226.4 $ 235.7

Gross profit $ 65.8 $ 60.4 $ 52.3 $ 61.5 Operating income (loss) from continuing operations $ 11.4 $ 8.9 $ 6.1 $ 5.4 Provision (benefit) for income taxes $ 2.8 $ (0.1 ) $ 0.2 $ (2.9 )

Net loss $ (10.3 ) $ (9.6 ) $ (9.9 ) $ (7.4 )

Net loss per common share:

F- 47

Condensed Consolidating Balance Sheet December 30, 2012 (in millions) Parent Company Guarantors on a Combined Basis Non- Guarantors on a Combined

Basis Eliminations Consolidated

Assets

Current Assets:

Cash and cash equivalents $ 37.8 $ (4.0 ) $ 15.2 $ — $ 49.0 Accounts receivable, net — 253.5 18.4 — 271.9 Amounts due from affiliated companies 480.2 — — (480.2 ) — Inventoried costs — 75.4 18.9 — 94.3 Other current assets 9.1 28.0 3.1 — 40.2 Total current assets 527.1 352.9 55.6 (480.2 ) 455.4 Property, plant and equipment, net 1.3 74.7 9.6 — 85.6 Goodwill — 574.7 21.7 — 596.4 Intangible assets, net — 103.4 2.7 — 106.1 Investment in subsidiaries 439.8 28.8 — (468.6 ) — Amounts due from affiliated companies — 24.0 — (24.0 ) — Other assets 17.6 22.4 0.4 — 40.4 Total assets $ 985.8 $ 1,180.9 $ 90.0 $ (972.8 ) $ 1,283.9

Liabilities and Stockholders' Equity

Current liabilities:

Accounts payable $ 2.8 $ 75.2 $ 5.6 $ — $ 83.6 Accrued expenses 7.0 42.3 3.4 — 52.7 Accrued compensation 2.9 41.8 3.1 — 47.8 Billings in excess of costs and earnings on

uncompleted contracts — 40.5 3.2 — 43.7 Deferred tax liability — 28.9 — — 28.9 Amounts due to affiliated companies — 455.1 25.1 (480.2 ) — Other current liabilities 1.1 19.1 1.9 — 22.1 Total current liabilities 13.8 702.9 42.3 (480.2 ) 278.8 Long-term debt, net of current portion 643.6 — 4.8 — 648.4 Deferred tax liability — — — — — Amounts due to affiliated companies — — 24.0 (24.0 ) — Other long-term liabilities 4.3 26.2 2.1 — 32.6 Total liabilities 661.7 729.1 73.2 (504.2 ) 959.8 Total stockholders' equity 324.1 451.8 16.8 (468.6 ) 324.1 Total liabilities and stockholders' equity $ 985.8 $ 1,180.9 $ 90.0 $ (972.8 ) $ 1,283.9

F- 48

Condensed Consolidating Balance Sheet December 29, 2013 (in millions) Parent Company Guarantors on a Combined Basis Non- Guarantors on a Combined

Basis Eliminations Consolidated

Assets

Current Assets:

Cash and cash equivalents $ 42.7 $ (3.0 ) $ 16.0 $ — $ 55.7 Accounts receivable, net — 238.6 27.2 — 265.8 Amounts due from affiliated companies 410.2 — — (410.2 ) — Inventoried costs — 59.1 15.5 — 74.6 Other current assets 10.7 19.4 4.1 — 34.2 Total current assets 463.6 314.1 62.8 (410.2 ) 430.3 Amounts due from affiliated companies, long-term — 24.0 — (24.0 ) — Property, plant and equipment, net 2.1 71.9 10.8 — 84.8 Goodwill — 574.8 21.6 — 596.4 Intangible assets, net — 68.5 1.4 — 69.9 Investment in subsidiaries 474.2 36.7 — (510.9 ) — Other assets 12.9 23.0 (0.7 ) — 35.2 Total assets $ 952.8 $ 1,113.0 $ 95.9 $ (945.1 ) $ 1,216.6

Liabilities and Stockholders' Equity

Current liabilities:

Accounts payable $ 2.8 $ 54.1 $ 5.0 $ — $ 61.9 Accrued expenses 6.6 40.9 3.9 — 51.4 Accrued compensation 4.0 36.9 4.0 — 44.9 Billings in excess of costs and earnings on

uncompleted contracts — 45.4 7.1 — 52.5 Deferred income tax liability — 28.4 — — 28.4 Amounts due to affiliated companies — 390.2 20.0 (410.2 ) — Other current liabilities 1.3 9.5 1.1 — 11.9 Total current liabilities 14.7 605.4 41.1 (410.2 ) 251.0 Long-term debt, net of current portion 639.5 — 3.8 — 643.3 Amounts due to affiliated companies — — 24.0 (24.0 ) — Other long-term liabilities 2.8 21.4 2.3 — 26.5 Total liabilities 657.0 626.8 71.2 (434.2 ) 920.8 Total stockholders' equity 295.8 486.2 24.7 (510.9 ) 295.8 Total liabilities and stockholders' equity $ 952.8 $ 1,113.0 $ 95.9 $ (945.1 ) $ 1,216.6

F- 49

Condensed Consolidating Statement of Operations and Comprehensive Income (Loss) Year Ended December 25, 2011

(in millions) Parent Company Guarantors on a Combined Basis Non- Guarantors on a Combined

Basis Eliminations Consolidated

Service revenues $ — $ 349.3 $ 1.7 $ — $ 351.0

Product sales — 327.4 46.9 (11.4 ) 362.9

Total revenues — 676.7 48.6 (11.4 ) 713.9 Cost of service revenues 259.2 1.5 260.7 Cost of product sales — 242.5 30.9 (11.4 ) 262.0

Total costs — 501.7 32.4 (11.4 ) 522.7 Gross profit — 175.0 16.2 — 191.2 Selling, general and administrative expenses 15.9 122.3 14.9 153.1 Research and development expenses — 7.9 0.7 — 8.6

Operating income (loss) from continuing operations (15.9 ) 44.8 0.6 — 29.5 Other income (expense):

Interest expense, net (50.8 ) 0.1 (0.4 ) (51.1 )

Other income, net 0.3 0.4 (0.7 ) — —

Total other income and expense, net (50.5 ) 0.5 (1.1 ) — (51.1 ) Income (loss) from continuing operations before

income taxes (66.4 ) 45.3 (0.5 ) — (21.6 ) Provision (benefit) for income taxes from continuing

operations 3.0 (1.1 ) — 1.9

Income (loss) from continuing operations (66.4 ) 42.3 0.6 — (23.5 ) Income (loss) from discontinued operations (0.8 ) 0.1 (0.7 )

Equity in net income (loss) of subsidiaries 42.2 0.5 — (42.7 ) —

Net income (loss) $ (24.2 ) $ 42.0 $ 0.7 $ (42.7 ) $ (24.2 )

F- 50

Condensed Consolidating Statement of Operations and Comprehensive Income (Loss) Year Ended December 30, 2012

(in millions) Parent Company Guarantors on a Combined Basis Non- Guarantors on a Combined

Basis Eliminations Consolidated

Service revenues $ — $ 448.5 $ 1.5 $ — $ 450.0

Product sales — 470.0 64.5 (15.3 ) 519.2

Total revenues — 918.5 66.0 (15.3 ) 969.2 Cost of service revenues 350.0 0.8 350.8 Cost of product sales — 333.8 42.7 (15.3 ) 361.2

Total costs — 683.8 43.5 (15.3 ) 712.0 Gross profit — 234.7 22.5 — 257.2 Selling, general and administrative expenses 7.4 171.2 13.9 192.5 Impairment of goodwill and intangibles 96.6 96.6 Research and development expenses — 16.9 0.9 — 17.8

Operating income (loss) from continuing

operations (7.4 ) (50.0 ) 7.7 — (49.7 ) Other income (expense):

Interest expense, net (65.9 ) 0.3 (0.5 ) (66.1 )

Other income, net 0.3 0.1 0.9 — 1.3

Total other income and expense, net (65.6 ) 0.4 0.4 — (64.8 ) Income (loss) from continuing operations before

income taxes (73.0 ) (49.6 ) 8.1 — (114.5 ) Provision (benefit) for income taxes from

continuing operations 20.8 (22.8 ) 0.4 — (1.6 )

Income (loss) from continuing operations (93.8 ) (26.8 ) 7.7 — (112.9 ) Income (loss) from discontinued operations (0.1 ) (2.2 ) 0.8 (1.5 )

Equity in net income (loss) of subsidiaries (20.5 ) 8.3 — 12.2 —

Net income (loss) $ (114.4 ) $ (20.7 ) $ 8.5 $ 12.2 $ (114.4 )

F- 51

Condensed Consolidating Statement of Operations and Comprehensive Income (Loss) Year Ended December 29, 2013

(in millions) Parent Company Guarantors on a Combined Basis Non-Guarantors on

a Combined Basis Eliminations Consolidated

Service revenues — 438.2 5.4 — 443.6

Product sales — 448.6 75.3 (16.9 ) 507.0

Total revenues — 886.8 80.7 (16.9 ) 950.6 Cost of service revenues 331.3 3.9 335.2 Cost of product sales — 338.9 53.4 (16.9 ) 375.4

Total costs — 670.2 57.3 (16.9 ) 710.6 Gross profit — 216.6 23.4 — 240.0 Selling, general and

administrative expenses 5.5 167.2 14.1 186.8 Impairment of goodwill and

intangibles — — — — —

Research and development

expenses — 20.2 1.2 — 21.4

Operating income (loss) from

continuing operations (5.5 ) 29.2 8.1 — 31.8 Other income (expense):

Interest expense, net (65.6 ) 2.3 (0.4 ) (63.7 )

Other income, net (0.3 ) 0.3 — —

Total other income and

expense, net (65.6 ) 2.0 (0.1 ) — (63.7 ) Income (loss) from continuing

operations before income taxes (71.1 ) 31.2 8.0 — (31.9 ) Provision (benefit) for income

taxes from continuing

operations 0.6 (0.7 ) 0.1 — —

Income (loss) from continuing

operations (71.7 ) 31.9 7.9 — (31.9 ) Income (loss) from

discontinued operations 0.1 (5.4 ) (5.3 )

Equity in net income (loss) of

subsidiaries 34.4 7.9 — (42.3 ) —

Net income (loss) $ (37.2 ) $ 34.4 $ 7.9 $ (42.3 ) $ (37.2 )

F- 52

Condensed Consolidating Statement of Cash Flows Year Ended December 25, 2011

(in millions) Parent Company Guarantors on a Combined Basis Non- Guarantors on a Combined

Basis Eliminations Consolidated

Net cash provided by (used in) operating activities $ (55.1 ) $ 60.5 $ (0.2 ) $ — $ 5.2 Investing activities:

Cash paid for acquisitions, net of cash acquired (421.0 ) 18.0 11.9 — (391.1 ) Decrease in restricted cash 1.4 1.6 — — 3.0 Investment in affiliated companies — (68.6 ) 68.6 —

Capital expenditures (0.2 ) (6.3 ) (1.0 ) — (7.5 ) Net cash provided by (used in) investing activities from

continuing operations (419.8 ) (55.3 ) 10.9 68.6 (395.6 ) Financing activities:

Proceeds from the issuance of common stock 61.1 — — — 61.1 Proceeds from the issuance of long-term debt 425.7 — — — 425.7 Debt issuance costs paid (22.1 ) — — — (22.1 ) Purchase of treasury stock (10.9 ) — — — (10.9 ) Repayment of debt — (2.6 ) (0.8 ) — (3.4 ) Financing from affiliated companies 63.6 — 5.0 (68.6 ) — Other, net 2.0 — — — 2.0 Net cash provided by (used in) financing activities from

continuing operations 519.4 (2.6 ) 4.2 (68.6 ) 452.4 Net cash flows of continuing operations 44.5 2.6 14.9 — 62.0 Net operating cash flows from discontinued operations — (2.2 ) (0.5 ) — (2.7 ) Effect of exchange rate changes on cash and cash

equivalents — (0.3 ) (0.2 ) (0.5 ) Net increase in cash and cash equivalents $ 44.5 $ 0.1 $ 14.2 $ — $ 58.8

Condensed Consolidating Statement of Cash Flows Year Ended December 30, 2012

(in millions) Parent Company Guarantors on a Combined Basis Non-Guarantors on

a Combined Basis Eliminations Consolidated

Net cash provided by (used in)

operating activities $ (98.2 ) $ 144.5 $ 6.0 $ — $ 52.3 Investing activities: — —

Cash paid for acquisitions, net of

cash acquired 2.3 (151.7 ) — — (149.4 ) Decrease in restricted cash — 0.6 — — 0.6 Investment in affiliated

companies (10.8 ) — (2.0 ) 12.8 —

Capital expenditures (0.5 ) (14.2 ) (1.9 ) — (16.6 )

Other, net — 0.3 — — 0.3

Net cash provided by (used in) investing activities from

continuing operations (9.0 ) (165.0 ) (3.9 ) 12.8 (165.1 ) Financing activities:

Proceeds from the issuance of

common stock 97.0 — — — 97.0

Debt issuance costs paid (1.2 ) — — — (1.2 ) Repayment of debt — (0.5 ) (1.0 ) — (1.5 ) Financings from affiliated

companies — 12.8 — (12.8 ) —

Other, net (3.4 ) — — — (3.4 )

Net cash provided by (used in) financing activities from

continuing operations 92.4 12.3 (1.0 ) (12.8 ) 90.9 Net cash flows of continuing

operations (14.8 ) (8.2 ) 1.1 — (21.9 ) Net operating cash flows from

discontinued operations — 1.3 — — 1.3

Effect of exchange rate changes on

cash and cash equivalents — — — —

Net increase (decrease) in cash and

F- 54

Condensed Consolidating Statement of Cash Flows Year Ended December 29, 2013

(in millions) Parent Company Guarantors on a Combined Basis Non-Guarantors on

a Combined Basis Eliminations Consolidated

Net cash provided by (used in)

operating activities $ (65.9 ) $ 87.5 $ 1.0 $ — $ 22.6 Investing activities: — —

Cash paid for acquisitions, net of

cash acquired — 2.2 — — 2.2

Decrease in restricted cash — 0.4 — — 0.4 Proceeds from the sale of

discontinued operations — 1.3 — — 1.3

Investment in affiliated

companies — (74.8 ) — 74.8 —

Capital Expenditures (1.4 ) (12.3 ) (2.9 ) — (16.6 ) Net cash provided by (used in)

investing activities from

continuing operations (1.4 ) (83.2 ) (2.9 ) 74.8 (12.7 ) Financing activities:

Cash paid for contingent

acquisition consideration — (2.1 ) — — (2.1 ) Repayment of debt — — (1.0 ) — (1.0 ) Purchase of ESPP shares 1.1 — — — 1.1 Financings from affiliated

companies 71.1 — 3.7 (74.8 ) —

Other, net — — — — —

Net cash provided by (used in) financing activities from

continuing operations 72.2 (2.1 ) 2.7 (74.8 ) (2.0 ) Net cash flows of continuing

operations 4.9 2.2 0.8 — 7.9

Net operating cash flows from

discontinued operations (1.3 ) (1.3 )

Effect of exchange rate changes on

cash and cash equivalents — — 0.1 — 0.1

Net increase (decrease) in cash and

Exhibit 21.1 List of Subsidiaries

Ai Metrix, Inc.

Delaware

Airorlite Communications, Inc.

New Jersey

Avtec Systems, Inc.

Virginia

Charleston Marine Containers, Inc.

Delaware

Composite Engineering, Inc.

California

Kratos Systems and Solutions, Inc.

Virginia

Dallastown Realty I, LLC

Delaware

Dallastown Realty II, LLC

Delaware

Defense Systems, Incorporated

Virginia

DEI Services Corporation

Florida

Digital Fusion Solutions, Inc.

Florida

Digital Fusion, Inc.

Delaware

Diversified Security Solutions, Inc.

New York

DTI Associates, Inc.

Virginia

EW Simulation Technology Ltd.

United Kingdom

General Microwave Israel (1987) Ltd.

Israel

General Microwave Israel Corporation

Delaware

General Microwave Corporation

New York

Gichner Europe Limited

United Kingdom

Gichner Systems Group, Inc.

Delaware

Gichner Systems International, Inc.

Delaware

Haverstick Consulting, Inc.

Indiana

Haverstick Government Solutions, Inc.

Ohio

Henry Bros. Electronics, Inc.

California

Henry Bros. Electronics, Inc.

Colorado

Henry Bros. Electronics, Inc.

Delaware

Henry Bros. Electronics, Inc.

New Jersey

Henry Bros. Electronics, Inc.

Virginia

Henry Bros. Electronics, LLC

Arizona

Herley GMI Eyal Ltd.

Israel

Herley Industries, Inc.

Delaware

Herley-CTI, Inc.

Delaware

Herley-RSS, Inc.

Delaware

HGS Holdings, Inc.

Indiana

Integral Systems Europe Ltd.

United Kingdom

Integral Systems Europe S.A.S.

France

JMA Associates, Inc.

Delaware