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1. Which of the following descriptions fits the definition of a confirmed pertussis case? a. an acute cough illness lasting 4 days occurring in an individual with at
least one pertussis-associated sign
b. an acute cough illness lasting 14 days or longer occurring in an individual with at least one pertussis-associated sign
c. a cough illness of any duration in an individual from whom Bordetella
pertussis was isolated
d. a condition meeting the clinical case definition, but is not laboratory- confirmed, or epidemiological linked to a laboratory-confirmed case of the disease
e. a condition meeting the clinical case definition, but is not
epidemiological linked to a laboratory-confirmed case of the disease
2. Bordetella pertussis is transmitted person-to-person by which of the following means? a. ticks
b. aerosolized droplets from a cough or sneeze c. contaminated food
d. blood or blood products e. animal bites
3. Which of the following choices best describes the members of the genus Bordetella? a. Gram-positive sporeforming, capsule producing rods, occurring in pairs b. Gram-negative sporeforming rods occurring singly or in pairs
c. Gram-negative small, capsule-producing rods exhibiting bipolar staining at times, and appearing singly or in pairs
d. Gram-positive small, capsule forming rods exhibiting bipolar staining at times e. Gram-negative, aerobic sporeforming coccobacilli
PERTUSSIS AND LEGIONELLOSIS
4. Which of the following antibiotics is the drug of choice for the treatment of children and adults with pertussis?
a. penicillin G b. streptomycin c. rifampin d. erythromycin
e. choices a and b combined
5. Which of the following listings of signs and symptoms is typical of the catarrhal stage of pertussis?
a. occurs from week 0 to 4; the onset is insidious; infants have a high fever, a productive cough, and do not exhibit coryza
b. occurs from week 0 to 1; the onset is insidious; infants have a mild fever, a non-productive cough, and exhibit coryza
c. occurs from 1 to 6; episodes of paroxysmal coughing occur up to 10 times/day for 2 to 6 weeks; the characteristic whoop follows a series of coughs as air is drawn through a narrowed glottis; no other signs or symptoms typically occur d. occurs from week 2 to 6; episodes of paroxysmal coughing occur up to 50
times/day for 2 to 4 weeks; the characteristic whoop follows a series of coughs as air is drawn through a narrowed glottis; other signs and symptoms include vomiting following the whoop (post-tussive vomiting), production of large amounts of mucoid secretions, respiratory distress, and the laboratory finding of a significant increase in lymphocytes with counts up to
40,000/mm3; pneumonia is a common occurrence with infants
e. occurs from week 3 to 12; the frequency and severity of paroxysmal coughing and the other signs and symptoms gradually fade
6. Which of the following products or substances associated with Bordetella pertussis is known to inhibit the phagocytosis of the pathogen by the infected host?
a. adenylate cyclase
b. filamentous hemagglutinin c. pertussis toxin
d. tracheal cytotoxin e. dermonecrotic toxin
PERTUSSIS AND LEGIONELLOSIS
7. Which of the following conditions is not a possible complication in infant pertussis cases? a. pneumonia caused by Streptococcus pneumoniae
b. seizures
c. non-productive cough d. encephalopathy
e. hemorrhaging events caused by high blood pressure exerted during coughing episodes
8. Which of the following time schedules is recommended by the ACIP regarding DTaP vaccines as a five-consecutive-dose series for children?
a. begin at 5, 6, and 8 months of age, followed by a fourth dose at 12 to 18 months of age and a fifth dose at 4 to 6 years of age
b. begin at 2, 4, and 6 months of age, followed by a fourth dose at 12 to 18 months of age and a fifth dose at 4 to 6 years of age
c. begin at 2, 4, and 6 months of age, followed by a fourth dose at 16 to 18 months of age and a fifth dose at 6 to 8 years of age
d. begin at 3, 6, and 9 months of age, followed by a fourth dose at 16 to 18 months of age and a fifth dose at 4 to 6 years of age
e. begin at 5, 6, and 8 months of age, followed by a fourth dose at 18 to 30 months of age and a fifth dose at 4 to 6 years of age
9. Which of the choices best describes the components of a DTaP vaccine?
a. diphtheria toxin, tetanus toxoid, and whole-cell Bordetella pertussis b. diphtheria toxoid, tetanus toxoid, and one or more purified components of Streptococcus pneumoniae
c. diphtheria toxoid, tetanus toxoid, and one or more purified components of B. pertussis
d. diphtheria toxin, tetanus toxin, and one or more purified components of Bordetella pertussis
e. none of these
10. Which of the following clinical diseases are the two main conditions caused by Legionella and grouped under the designation legionellosis?
a. Legionnaires’ disease and pneumonia b. Legionnaires’ disease and pericarditis c. Pontiac fever and pneumonia
d. Pontiac fever and Legionnaires’ disease
PERTUSSIS AND LEGIONELLOSIS
11. Which of the following descriptions is correct for members of the genus Legionella? a. Gram-negative, small, motile capsule forming rods
b. Gram-positive, small, non-motile capsule forming rods
c. Gram-negative, small, motile, non-capsule forming, non-sporeforming rods d. Gram-positive, small, motile, non-capsule forming, non-sporeforming rods e. Gram-negative, small, motile, capsule forming, sporeforming cocci
12. Which of the following is not considered to be risk factors for legionellosis? a. chronic lung disease
b. immunocompetence c. cigarette smoking d. immunosuppression e. surgery
13. The transmission of L. pneumophila largely occurs by individuals being exposed to which of the following?
a. aerosols created by the various human-made habitats b. ingestion of contaminated food
c. infected flies d. infected mosquitoes
e. contaminated blood or blood products
14. Which of the following pathogenic Legionella species is known as the Pittsburgh pneumonia agent? a. L. pneumophila b. L. bozemanii c. L. longbeachae d. L. wadsworthii e. L. micadadei
15. Which of the following descriptions best describes the typical signs and symptoms found with case of Legionnaires’ disease?
a. fever, stupor, and constipation
b. respiratory failure, headache, productive cough, and bloody stool
c. headache, muscle pain, non-productive cough, appetite loss, temperature 38o C., non-productive cough, and diarrhea accompanied by watery stools
d. fever, muscle pain, slightly productive cough, temperature 40o C. or above, chest pain, and diarrhea accompanied by bloody stools
e. fever, headache, muscle pain, chest pain, non-productive cough, loss of appetite and watery stools