Struct. unknown. Alkaloid from Sophora microphylla (Fabaceae). Mp 168-1718.
Briggs, L.H. et al., J.C.S., 1937, 1795 (isol)
A-506
Voacanga thouarsii Alkaloid
E
[50924-06-6]
C43H50N4O7 734.891
Bisindole alkaloid. Struct. unknown.
Alkaloid from the leaves of Voacanga thouarsii (Apocynaceae). Cryst. (MeOH).
Mp 235-2388. [a]D-140. Intense blue col.
with HNO3. lmax225 (log e 4.66); 265 (log e 4.08); 283 (sh) (log e 3.96); 291 (sh) (log e 3.9) (EtOH).
Rolland, Y. et al., Phytochemistry, 1973, 12, 2039-2042 (isol, uv, ir, pmr)
A-507
Buxus Alkaloid F
Struct. unknown. Alkaloid from Buxus wallichiana (Buxaceae).
Mp 1908. [a]28D +26.6 (c, 0.76 in EtOH).
MW 442.
Vassova´, A. et al., Pharmazie, 1970, 25, 363;
CA, 73, 127748n
A-508
Dendrobates Alkaloid 223F
C14H25NO 223.358
Struct. unknown. Trace alkaloid from skin extracts of an undescribed Dendro-bates sp. from Panama (Dendrobatidae).
Mol. formula tentative; m/e 223 (1), 138 (100). H2-deriv, m/e 225, 182.
Daly, J.W. et al., Prog. Chem. Org. Nat. Prod., 1982, 41, 205 (ms, rev)
A-509
Dendrobates Alkaloid 251F
Dodecahydro-3,7,10-trimethylcyclopen-ta[b]quinolizine-2-methanol, 9CI. Indoli-zidine 251F
Major alkaloid from the skin extracts of the Colombian dendrobatid frog Minyo-bates bombetes. Pale yellow oil. [a]D-11.1 (c, 0.96 in MeOH).
Aldehyde: Dodecahydro-3,7,10-trimethyl- cyclopenta[b]quinolizine-2-carboxalde-hyde, 9CI. Dendrobates Alkaloid 249B.
Indolizidine 249B [142543-05-3]
C16H27NO 249.395
Alkaloid from Minyobates bombetes.
Tentative struct.
2,3,6,7-Tetradehydro: Dendrobates Alka-loid 247
[142543-06-4]
C16H25NO 247.38
Alkaloid from Minyobates bombetes.
Tentative struct.
2,3,6,7-Tetradehydro, aldehyde: Dendro-bates Alkaloid 245
[142543-07-5]
C16H23NO 245.364
Alkaloid from Minyobates bombetes.
Tentative struct.
Deoxy: Dodecahydro-2,3,7,10-tetra-methylcyclopenta[b]quinolizine, 9CI.
Dendrobates Alkaloid 235H. Indolizi-dine 235H
[142543-02-0]
C16H29N 235.412
Alkaloid from Minyobates bombetes.
Tentative struct.
Deoxy, 2j-hydroxy: Dodecahydro- 2,3,7,10-tetramethylcyclopenta[b]qui-nolizin-2-ol, 9CI. Dendrobates Alkaloid 251J. Indolizidine 251J
[142543-08-6]
C16H29NO 251.411
Alkaloid from Minyobates bombetes.
Tentative struct.
2-Epimer: Dendrobates Alkaloid 251F?.
Indolizidine 251F?
[142631-46-7]
C16H29NO 251.411
Alkaloid from Minyobates bombetes.
Tentative struct.
Homologue (R = CH3): Dodecahydro- 3,4,7,10-tetramethylcyclopenta[b]qui-nolizine-2-methanol, 9CI. Dendrobates Alkaloid 265B. Indolizidine 265B [142543-03-1]
C17H31NO 265.438
Alkaloid from Minyobates bombetes.
Tentative struct.
Homologue (R = CH2CH3): 4-Ethyldo- decahydro-3,7,10-trimethylcyclopen-ta[b]quinolizine-2-methanol, 9CI.
Dendrobates Alkaloid 279B. Indolizi-dine 279B
[142543-04-2]
C18H33NO 279.465
Alkaloid from Minyobates bombetes.
Tentative struct.
Homologue (R = CH2CH3), deoxy, 2j-hydroxy: 4-Ethyldodecahydro-2,3,7,10- tetramethylcyclopenta[b]quinolizin-2-ol, 9CI. Dendrobates Alkaloid 279C.
Indolizidine 279C [142543-09-7]
C18H33NO 279.465
Alkaloid from Minyobates bombetes.
Tentative struct.
Spande, T.F. et al., J. Nat. Prod., 1992, 55, 707-722 (isol, pmr, ms)
Taber, D.F. et al., J.A.C.S., 1995, 117, 5757-5762 (synth, pmr, cmr)
Wrobleski, A. et al., J.A.C.S., 2004, 126, 5475-5481 (synth)
A-510
Mantella Alkaloid 221F
N
OH H
C14H23NO 221.342
Structure tentatively reassigned in 2005. Trace alkaloid from skin extracts of the Madagascan frog Mantella aurantiaca.
Garraffo, H.M. et al., J. Nat. Prod., 1993, 56, 1016-1038 (isol, ms)
Adriamaharavo, N.R. et al., J. Nat. Prod., 2005, 68, 1743-1748 (struct)
A-511
Mantella Alkaloid 241F
8-(3-Butynyl)octahydro-5-(2-penten-4-ynyl)indolizine, 9CI. Indolizidine 241F [151805-25-3]
Provisional struct. Minor alkaloid from skin extracts of 2 populations of the Madagascan frog Mantella madagascar-iensis.
2?,3?-Dihydro: 8-(3-Butynyl)octahydro-5-(4-pentynyl)indolizine, 9CI. Mantella Alkaloid 243B. Indolizidine 243B [151805-26-4]
C17H25N 243.391
Trace alkaloid in one population of Mantella madagascariensis. Provisional struct.
3??,4??-Dihydro: 8-(3-Butenyl)octahydro-5-(2-penten-4-ynyl)indolizine, 9CI.
Mantella Alkaloid 243C. Indolizidine 243C
[151805-27-5]
C17H25N 243.391
Minor or trace alkaloid in 2 popula-tions of Mantella madagascariensis.
Provisional struct.
2?,3?,3??,4??-Tetrahydro: 8-(3-Butenyl)oc-tahydro-5-(4-pentynyl)indolizine, 9CI.
Mantella Alkaloid 245B. Indolizidine 245B
[151805-28-6]
C17H27N 245.407
Skytanthus acutus Alkaloid E Mantella Alkaloid 241F A-504 A-511
Trace alkaloid in 1 population of Mantella madagascariensis. Provisional struct.
Garraffo, H.M. et al., J. Nat. Prod., 1993, 56, 1016 (isol, ir, ms)
A-512
Mantella Alkaloid 249F
Homopumiliotoxin 249F
Struct. and MF unknown. Trace alkaloid from skin extracts of one population of the Madagascan frog Mantella madagas-cariensis.
Garraffo, H.M. et al., J. Nat. Prod., 1993, 56, 1016-1038 (isol, ir, ms)
A-513
Mantella Alkaloid 265F
C16H27NO2 265.395
Struct. unknown. May be related to alkaloids of the 235C class. Trace alka-loid from skin extracts of the Madagas-can frog Mantella aurantiaca.
Garraffo, H.M. et al., J. Nat. Prod., 1993, 56, 1016-1038 (isol, ms)
A-514
Mantella Alkaloid 281F
Struct. unknown. Probably belongs to the pumiliotoxin A class of alkaloid (see Pumiliotoxin A, P-791). Alkaloid from skin extracts of two populations of the Madagascan frog Mantella madagascar-iensis.
Garraffo, H.M. et al., J. Nat. Prod., 1993, 56, 1016-1038 (isol, ir, ms)
A-515
Pandaca caducifolia
Alkaloid F
C40H46N4O4 646.828
Struct. unknown. Bisindole alkaloid.
Alkaloid from Pandaca caducifolia (Apocynaceae). Noncryst. [a]D+56 (MeOH).
Zeches, M. et al., Phytochemistry, 1975, 14, 1122-1124 (isol, uv, ir, pmr)
A-516
Lycopodium Alkaloid G
Lycopodium Base G C18H27NO3 305.416
Struct. unknown. Alkaloid from Lyco-podium fawcettii (Lycopodiaceae). Mp 198-2008 (as perchlorate).
Burnell, R.H. et al., J.C.S., 1959, 3091 (isol, ir)
A-517
Mantella Alkaloid 207G
Homopumiliotoxin 207G
Struct. and MF unknown. Trace alkaloid from skin extracts of the Madagascan frog Mantella viridis.
Garraffo, H.M. et al., J. Nat. Prod., 1993, 56, 1016-1038 (isol, ms)
A-518
Pandaca caducifolia Alkaloid
G
C40H46N2O4 618.814
Struct. unknown. Bisindole alkaloid.
Alkaloid from Pandaca caducifolia (Apocynaceae). Noncryst. [a]D+35 (MeOH).
Zeches, M. et al., Phytochemistry, 1975, 14, 1122-1124 (isol, uv, ir, pmr)
A-519
Voacanga thouarsii
Alkaloid G
[50923-99-4]C42H50N4O5 690.881
Bisindole alkaloid. Struct. unknown.
Alkaloid from the leaves of Voacanga thouarsii (Apocynaceae). Cryst.
(Et2O). Mp 280-2858 dec. [a]D+46.
Pink col. with HNO3. lmax221 (log e 4.63); 260 (log e 4.29); 298 (log e 3.7) (EtOH).
Rolland, Y. et al., Phytochemistry, 1973, 12, 2039-2042 (isol, uv, ir, pmr)
A-520
Alkaloid 251G
[97380-38-6]
C15H25NO2 251.368
Struct. unknown. Alkaloid from skin extracts of the Madagascan frog Mantella aurantiaca (family Ranidae, subfamily Mantellinae). m/e 251 (26), 250 (45), 162 (100). Forms H2-deriv.
Two exchangeable hydrogens. Hydroxy congener of Alkaloid 235C. Has not been detected in dendrobatid frogs.
Daly, J.W. et al., Toxicon, 1984, 22, 905-919 (isol, ms)
A-521
Alkaloid GB14
C24H33NO5 415.528
Struct. unknown. Alkaloid from the bark of Himantandra belgraveana (Galbulimi-ma belgraveana) (Hi(Galbulimi-mantandraceae).
Prisms + 1H2O (Me2CO/heptane). Mp
Struct. unknown. Alkaloid from the bark of Himantandra (Galbulimima) belgra-veana (Himantandraceae). Needles (C6H6). Mp 2308. [a]D+58 (c, ca. 1 in
Struct. unknown. Alkaloid from the bark of Himantandra (Galbulimima) belgra-veana (Himantandraceae). Prisms (EtOAc). Mp 2038. [a]D+550 (c, ca. 1 in
Struct. unknown. Alkaloid from the bark of Himantandra (Galbulimima) baccata (Himantandraceae). Needles + 1H2O (MeOH aq.). Mp 1158. [a]D-21 (c, ca. 1
Struct. unknown. Alkaloid from the bark of Himantandra baccata (preferred genus name Galbulimima) (Himantandraceae).
Prisms (heptane). Mp 1208. [a]D+37 (c, ca. 1 in CHCl3).
Binns, S.V. et al., Aust. J. Chem., 1965, 18, 569-573 (isol)
A-526
Gentiana Alkaloid II
Struct. unknown. Monoterpene alkaloid.
Alkaloid from Gentiana asclepiadea, Gentiana bulgarica, Gentiana cruciata, Gentiana lutea and Gentiana punctata (Gentianaceae).
Mollov, N.M. et al., Dokl. Bulg. Akad. Nauk, 1965, 18, 947; CA, 64, 10084h (isol, ir) Cordell, G.A. et al., Alkaloids (Academic
Press), 1977, 16, 431 (rev)
A-527
Sternbergia Alkaloid III
Sternbergia Base III
Amaryllidaceae alkaloid. Struct. un-known. Isol. from Sternbergia fischeriana (Amaryllidaceae). Mp 212-2138. Opt.
inactive, mol. formula not recorded.
Hydrobromide: Mp 174-1758.
Picrate: Mp 217-2198.
Proskurnina, N.F. et al., Chem. Zentralbl., 1954, 125, 8353 (isol)
A-528
Solanum Alkaloid IV
Struct. unknown. A glycoalkaloid cont.
NH, OH and conjugated C .O. Isol.
from epigeal parts of Solanum nigrum (Solanaceae). Cryst. (MeOH). Mp 320-3258. Cooccurs with Solasonine, Sola-margine and b-SolaSola-margine (see Spiro-sol-5-en-3-ol, S-456).
Aslanov, S.M. et al., Khim. Prir. Soedin., 1971, 7, 674; Chem. Nat. Compd. (Engl. Transl.), 1971, 7, 658
A-529
Ungernia Alkaloid IV
Ungernia Base IV
Amaryllidaceae alkaloid. Struct. un-known. Isol. from the leaves of Ungernia minor (Amaryllidaceae). Cryst. (MeOH).
Mp 193-1948.
Normatov, M. et al., Uzb. Khim. Zh., 1965, 9, 25-30; CA, 63, 7061f (isol)
A-530
Gentiana cruciata Alkaloid
IVb
C10H16N2O7 276.246
Struct. unknown. Monoterpene alkaloid.
Alkaloid from Gentiana cruciata (Gen-tianaceae). Mp 138-1408.
Marekov, N. et al., Dokl. Bulg. Akad. Nauk, 1965, 18, 999-1002; CA, 64, 11270a (isol, ir) Cordell, G.A. et al., Alkaloids (Academic
Press), 1977, 16, 431-510 (rev)
A-531
Lycopodium annotinum
Al-kaloid IX
Lycopodium Base IX C17H25NO2 275.39
Struct. unknown. Alkaloid from Lyco-podium annotinum (Lycopodiaceae).
Mantella Alkaloid 249F Lycopodium annotinum Alkaloid IX A-512 A-531
Methiodide: Mp 3248. [a]20D -49.8.
Methochloride: Mp 2748.
Methoperchlorate: Mp 3168.
Methopicrate: Mp 78-808.
Achmatowicz, O. et al., Pol. J. Chem. (Rocz.
Chem.), 1958, 32, 485 (isol, uv)
A-532
C-Alkaloid J
C19H21N2 277.388
Struct. unknown. Alkaloid from calabash curare (Strychnos spp.) (Loganiaceae).
Mp 2608 dec. (as picrate). Red-orange col. with Ce(SO4)2.
Kebrle, J. et al., Helv. Chim. Acta, 1953, 36, 102-121 (isol, uv)
A-533
Mantella Alkaloid 207J
Struct. and MF unknown. Possibly a homologue of Precoccinelline in D-886.
Trace alkaloid from skin extracts of one population of the Madagascan frog Mantella madagascariensis.
Garraffo, H.M. et al., J. Nat. Prod., 1993, 56, 1016-1038 (isol, ir, ms)
A-534
Mantella Alkaloid 235J
Homopumiliotoxin 235J
Struct. and MF unknown. Trace alkaloid from skin extracts of one population of the Madagascan frog Mantella madagas-cariensis.
Garraffo, H.M. et al., J. Nat. Prod., 1993, 56, 1016-1038 (isol, ir, ms)
A-535
Mantella Alkaloid 235K
Struct. and MF unknown. Considered to be a tricyclic alkaloid. Trace alkaloid from skin extracts of the Madagascan frog Mantella betsileo.
Garraffo, H.M. et al., J. Nat. Prod., 1993, 56, 1016-1038 (isol, ms)
A-536
Alkaloid K2
C21H27NO6 389.447
Struct. unknown. Alkaloid from the above-ground parts of Colchicum kessel-ringii (Liliaceae). Mp 226-2288.
Methiodide: Mp 247-2498.
Yusupov, M.K. et al., J. Gen. Chem. USSR (Engl. Transl.), 1964, 34, 1682 (isol)
A-537
Alkaloid from the above-ground parts of Colchicum kesselringii (Liliaceae). Mp 238-2408 (natural) Mp 259-2608 (semi-synthetic). [a]20D -152 (c, 0.92 in MeOH) (semisynthetic).
Ac:
Cryst. (Et2O/CHCl3). Mp 230-2328.
[a]22D -150 (c, 1.0 in MeOH).
Me ether: Allocolchicine. Suhailamine.
Alkaloid K3 [641-28-1]
C22H25NO6 399.443
Alkaloid from the flowers of Colchi-cum autumnale, from ColchiColchi-cum dec-aisnei and above ground parts of Colchicum kesselringii (Liliaceae).
Cryst. (Et2O/CHCl3) or amorph. solid.
Mp 257-2588. [a]22D-150 (c, 1.2 in MeOH) (semisynthetic). First descr. as Alkaloid K3 without abs. config. or opt. rotn. Suhailamine (1991) assigned (S)-config. However, spectroscopic and phys. props. of authentic Allocolchi-cine differ from those of Suhailamine and therefore the true struct. of the latter remains unclear.
-HO7884000
Yusupov, M.K. et al., Zh. Obshch. Khim., 1964, 34, 1677-1680; J. Gen. Chem. USSR (Engl. Transl.), 1964, 34, 1686-1688 (isol struct)
Yusupov, M.K. et al., Khim. Prir. Soedin., 1973, 9, 194-196; Chem. Nat. Compd. (Engl.
Transl.), 1973, 9, 188-189
Mackay, M.F. et al., Acta Cryst. C, 1989, 45, 795-799 (Allocolchicine, cryst struct) Abu Zarga, M.H. et al., J. Nat. Prod., 1991,
54, 936-940 (Suhailamine)
Banwell, M.G. et al., Chem. Comm., 1994, 2647-2649 (Suhailamine)
Leblanc, M. et al., Org. Lett., 2005, 7, 2849-2852 (synth)
A-538
Alkaloid K5
C19H25NO4 331.411
Struct. unknown. Alkaloid from the above-ground parts of Colchicum kessel-ringii (Liliaceae). Mp 224-2268.
Hydrochloride: Mp 239-2418.
Methiodide: Mp 278-2808.
Yusupov, M.K. et al., J. Gen. Chem. USSR (Engl. Transl.), 1964, 34, 1682 (isol)
A-539
Alkaloid K6
Struct. unknown. Alkaloid from the above-ground parts of Colchicum kessel-ringii (Liliaceae).
Methiodide: Mp 253-2548.
Yusupov, M.K. et al., J. Gen. Chem. USSR (Engl. Transl.), 1964, 34, 1682 (isol)
A-540
Alkaloid K7
C21H29NO4 359.464
Struct. unknown. Alkaloid from the above-ground parts of Colchicum kessel-ringii (Liliaceae). Mp 144-1468.
Hydrochloride: Mp 232-2348.
Methiodide: Mp 247-2488.
Yusupov, M.K. et al., J. Gen. Chem. USSR (Engl. Transl.), 1964, 34, 1682 (isol)
A-541
Alkaloid K9
Struct. unknown. Alkaloid from the above-ground parts of Colchicum kessel-ringii (Liliaceae).
Methiodide: Mp 245-2478.
Yusupov, M.K. et al., J. Gen. Chem. USSR (Engl. Transl.), 1964, 34, 1682 (isol)
A-542
Alkaloid K10
C18H23NO4 317.384
Struct. unknown. Alkaloid from the above-ground parts of Colchicum kessel-ringii (Liliaceae). Cryst. (Me2CO/
MeOH). Mp 232-2348.
Hydrochloride: Mp 261-2638.
Methiodide: Mp 249-2518.
Yusupov, M.K. et al., J. Gen. Chem. USSR (Engl. Transl.), 1964, 34, 1682 (isol)
A-543
Alkaloid K11
Struct. unknown. Alkaloid from the above-ground parts of Colchicum kessel-ringii (Liliaceae). Mp 274-2768.
Yusupov, M.K. et al., J. Gen. Chem. USSR (Engl. Transl.), 1964, 34, 1682 (isol)
A-544
C-Alkaloid L
Struct. unknown. Alkaloid from calabash curare (Strychnos spp.) (Loganiaceae).
Prisms (Me2CO aq.) (as picrate). Mp 1718 (picrate). Red col. with Ce(SO4)2. Kebrle, J. et al., Helv. Chim. Acta, 1953, 36,
102-121 (isol, uv)
A-545
Colubrina Alkaloid L
C37H40N2O6 608.733
Bisbenzylisoquinoline alkaloid. Struct.
unknown. Alkaloid from the stem bark of Colubrina faralaotra ssp. faralaotra (Rhamnaceae).
Guinaudeau, H. et al., Planta Med., 1975, 27, 304-318 (isol, uv, pmr, ms)
A-546
Mantella Alkaloid 251L
Homopumiliotoxin 251L
Struct. and MF unknown. Occurs mainly as the O-Ac deriv. Trace alkaloid from skin extracts of one population of the Madagascan frog Mantella madagascar-iensis.
Garraffo, H.M. et al., J. Nat. Prod., 1993, 56, 1016-1038 (isol, ir, ms)
A-547
Alkaloid L10
C16H27NO 249.395
Struct. unknown. Alkaloid from Lyco-podium annotinum (Lycopodiaceae). Mp 2238 (as perchlorate).
Manske, R.H.F. et al., Can. J. Res., Sect. B, 1943, 21, 92-96 (isol)
A-548
Alkaloid LA 4
[116097-93-9]
Alkaloid artifact generated by NH3and secoiridoid glucoside from ripe fruits of the common privet Ligustrum vulgare (Oleaceae). Semi-solid. [a]20D -0.23 (c, 1.0 in EtOH).
Willems, M. et al., Arch. Pharm. (Weinheim, Ger.), 1988, 321, 229 (isol, uv, ir, pmr, cmr, ms, struct)
C-Alkaloid J Alkaloid LA 4 A-532 A-548
A-549
Alkaloid LA 5
[115531-75-4]
As Alkaloid LA 4, A-548 with R = CH3
C20H24N2O4 356.421
Alkaloid artifact generated by NH3and secoiridoid glucosides from ripe fruit of the common privet Ligustrum vulgare (Oleaceae). Semi-solid. [a]20D -0.39 (c, 1.0 in EtOH).
Willems, M. et al., Arch. Pharm. (Weinheim, Ger.), 1988, 321, 229 (isol, uv, ir, pmr, cmr, ms, struct)
A-550
Alkaloid LA 6
[113145-61-2]
CH COOCH CH2 2 2 OH H CH C3 2 COOMe
N C19H21NO5 343.379
Alkaloid artifact generated by NH3and secoiridoid glucosides from ripe fruits of the common privet Ligustrum vulgare (Oleaceae). Needles (EtOAc/MeOH). Mp 115-1168.
Willems, M. et al., Arch. Pharm. (Weinheim, Ger.), 1987, 320, 1245 (isol, uv, ir, pmr, cmr, ms, struct)
A-551
Alkaloid LA 9
[116057-84-2]
Alkaloid artifact generated by NH3and secoiridoid glucosides from ripe fruits of the common privet Ligustrum vulgare (Oleaceae). Cryst. (EtOAc/MeOH). Mp 64-668. [a]20D -0.1 (c, 1.0 in EtOH).
Willems, M. et al., Arch. Pharm. (Weinheim, Ger.), 1988, 321, 357 (isol, uv, ir, pmr, cmr, struct)
A-552
Alkaloid LB1
Prob. a spermidine related alkaloid.
Struct. unknown. Minor alkaloid from the seeds of Lunaria biennis (Brassica-ceae). Mp 2208 dec.
Hairs, E. et al., Bull. Acad. R. Med. Belg., 1909, 1042-1048; CA, 1892, 4, 1042 (isol)
A-553
CAS numbering shown. Minor alkaloid from the seeds of Lunaria biennis (Bras-sicaceae). Amorph.
22-Ketone: Alkaloid LBX [38143-10-1]
C26H31N3O4 449.549
Minor alkaloid from the seeds of Lunaria biennis (Brassicaceae). Cryst.
(MeOH/Me2CO or MeOH/Et2O). Mp 2508 dec. [a]20D +201 (c, 0.6 in CHCl3).
Doskotch, R.W. et al., Experientia, 1972, 28, 382 (struct)
Poupat, C. et al., Tetrahedron, 1972, 28, 3087 (uv, ir, pmr, struct)
A-554
Alkaloid LC2
3-(3-Butenyl)-1,2,3,4,5,6,11,11a-octahy- dro-1,5-methano-10H-pyrido[1,2-a][1,5]diazocin-10-one, 9CI. 1,13-Dide-hydro-10,11-secomultiflorine.
Struct. revised in 1988. Some isolates were prev. reported erroneously as N-methy-lalbine (see Albine, A-243). Alkaloid from the leaves and seeds of Lupinus cosentinii, Lupinus albus and Lupinus formosus (Fabaceae). Cryst. (cyclohexane). Mp 608. [a]25D -520 (c, 1.0 in MeOH).
[97906-66-6 , 6822-63-5 ]
Beck, A.B. et al., J. Nat. Prod., 1979, 42, 385 (isol, uv, ir, pmr, ms, struct)
Wysocka, W. et al., Planta Med., 1988, 54, 522 (cmr, ms, struct)
Brukwicki, T. et al., J. Mol. Struct., 1989, 196, 343 (cmr, conform, bibl)
Wyrzykiewicz, E. et al., Org. Mass Spectrom., 1990, 25, 453 (ms)
Dutkiewicz, G. et al., Acta Cryst. C, 1995, 51, 1182 (cryst struct)
A-555
Truxillate-type dimer of Epilupinyl trans-ferulate in E-95. Alkaloid from leaves of
Lupinus cosentinii (Fabaceae). Cryst.
(MeOH/CHCl3). Mp 2288. [a]25D+23 (c, 1 in CHCl3/MeOH 1:1).
Beck, A.B. et al., J. Nat. Prod., 1979, 42, 385 (isol, struct, uv, ir, pmr, ms)
A-556
Alkaloid LE1
C28H47N3O 441.699
Struct. unknown. Alkaloid from Lyco-podium erythraeum (Lycopodiaceae).
MacLean, D.B. et al., Alkaloids (Academic Press), 1985, 26, 241
A-557
Alkaloid LO1
C31H39N3O2 485.668
Struct. unknown. Alkaloid from Lyco-podium obtusifolium (Lycopodiaceae).
MacLean, D.B. et al., Alkaloids (Academic Press), 1985, 26, 241
A-558
Alkaloid LO2
C30H49N3O 467.737
Struct. unknown. Alkaloid from Lyco-podium obtusifolium (Lycopodiaceae).
MacLean, D.B. et al., Alkaloids (Academic Press), 1985, 26, 241
A-559
Alkaloid LO3
C29H49N3 439.726
Struct. unknown. Alkaloid from Lyco-podium obtusifolium (Lycopodiaceae).
MacLean, D.B. et al., Alkaloids (Academic Press), 1985, 26, 241
A-560
Alkaloid LS14
C30H49N3O 467.737
Struct. unknown. Alkaloid from Lyco-podium saururus (Lycopodiaceae).
MacLean, D.B. et al., Alkaloids (Academic Press), 1985, 26, 241
A-561
Alkaloid LV1$
C15H22N2O 246.352
Not the same as Alkaloid LV1, A-562.
Struct. unknown. Alkaloid from Lupinus digitatus (Fabaceae). Needles (Me2CO/
petrol). Mp 108-1098. [a]D-314 (MeOH).
Deep-red col. with FeCl3. Perchlorate:
Cream needles +1=2H2O (EtOH). Mp 160-1628 dec. Cryst. with difficulty.
Methiodide:
Cream nodules (EtOH). Mp 246-2488 dec.
Crow, W.D. et al., Aust. J. Chem., 1955, 8, 136-139; 1957, 10, 177-181
Gladstones, J.S. et al., J. R. Soc. West. Aust., 1958, 41, 29
A-562
Alkaloid LV1$
C29H45N3 435.695
Not the same as Alkaloid LV1, A-561. Struct. unknown. Alkaloid from Lycopodium verticillatum (Lycopodia-ceae).
MacLean, D.B. et al., Alkaloids (Academic Press), 1985, 26, 241
A-563
Alkaloid LV2
C15H24N2O2 264.367
Alkaloid LA 5 Alkaloid LV2 A-549 A-563
Struct. unknown. Tentative mol. formu-la. Trace alkaloid from seeds of Lupinus varius (Fabaceae).
Struct. unknown. Alkaloid from Lupinus digitatus (Fabaceae). Needles (MeOH).
Mp 232-2338 dec. Conts. one OMe group. lmax235 nm. Possibly the mono-mer of Alkaloid LC7, A-555.
Picrate:
Yellow needles (Me2CO aq.). Mp 1868.
Dec. sharply at 2318.
Crow, W.D. et al., Aust. J. Chem., 1957, 10, 177-181
Gladstones, J.S. et al., J. R. Soc. West. Aust., 1958, 41, 29
A-565
Alkaloid LV4
C17H23NO5 321.372
Provisional mol. formula. Struct. un-known. Alkaloid from Lupinus digitatus (Fabaceae). Needles (CHCl3/petrol). Mp 235-2378 dec.
Crow, W.D. et al., Aust. J. Chem., 1957, 10, 177-181
Gladstones, J.S. et al., J. R. Soc. West. Aust., 1958, 41, 29
A-566
Buxus Alkaloid M$
See also Buxus Alkaloid M, A-567.
Struct unknown. Alkaloid from Buxus wallichiana (Buxaceae). Mp 2618. [a]23D
+27 (c, 0.33 in CHCl3).
Vassova´, A. et al., Pharmazie, 1970, 25, 363-365; CA, 73, 127748n
A-567
Buxus Alkaloid M$
C27H46N2O 414.673
Struct. unknown. Alkaloid from Buxus sempervirens (Buxaceae). Mp 203-2058.
[a]D-80 (CHCl3).
Friedrich, W. et al., Helv. Chim. Acta, 1950, 33, 873-878 (isol)
A-568
C-Alkaloid M
C20H23N2O2 323.414
Struct. unknown. Minimum formula.
Alkaloid from calabash curare (Strychnos spp.) (Loganiaceae). Slowly developing yellow col. with Ce(SO4)2.
Asmis, H. et al., Helv. Chim. Acta, 1954, 37, 1968-1973 (isol, uv)
A-569
Alkaloid MB 10
C23H30N2O5 414.5
Struct. unknown. Alkaloid from roots of Rauwolfia mombasiana (Apocynaceae).
Off-white amorph. powder. Conts. 2 OMe groups.
Iwu, M.M. et al., Planta Med., 1980, 38, 260-263 (isol, uv, ir, ms)
A-570
Buxus Alkaloid N
C22H35NO2 345.524
Struct. unknown. Poss. identical with Buxtauine M, B-482. Alkaloid from
Buxus sempervirens (Buxaceae). Mp 178-1798. [a]D+150 (CHCl3). Props. corresp.
to Buxtauine M, B-482.
Friedrich, W. et al., Helv. Chim. Acta, 1950, 33, 873-878 (isol)
A-571
Alkaloid ND 370
[37304-95-3]
Alkaloid from the bark of Nauclea diderrichii (Rubiaceae). Cryst. by subl.
Mp 209-2118.
MacLean, S. et al., Can. J. Chem., 1972, 50, 1496; 1976, 54, 1262 (uv, ir, pmr, ms, struct)
A-572
Quaternary alkaloid from calabash cur-are and Strychnos guianensis (Logania-ceae). Mp 288-2898 dec. (as chloride).
[a]22D -150 (c, 0.283 in 5%Py aq.) (as chloride). lmax227 (log e 4.1); 266 (log e 3.88); 282 (log e 3.77); 291 (log e 3.73) (MeOH).
Giesbrecht, E. et al., Helv. Chim. Acta, 1954, 37, 1974-1982 (isol)
Borris, R.P. et al., Helv. Chim. Acta, 1983, 66, 405 (struct, spectra)
Penelle, J. et al., Phytochemistry, 2000, 53, 1057-1066; 2001, 58, 619-626 (isol, uv, ir, cd, pmr, cmr, activity)
A-573
Alkaloid Or
2Struct. unknown
Alkaloid from Papaver orientale and Papaver pseudo-orientale (Papaveraceae).
Cryst. (petrol). Mp 124-1278 (120-1218).
Unstable, not obt. completely pure. m/e 333.
De´lenk-Heydenreich, K. et al., Pharmazie, 1969, 24, 635-645 (isol, uv, ms) Shafiee, A. et al., J. Pharm. Sci., 1975, 64,
1570-1572 (isol, uv, pmr)
A-574
Baptisia Alkaloid P
2C11H18N2O 194.276
Struct. unknown. Isol. from Baptisia
australis and Baptisia perfoliata. Cryst.
(MeOH/Et2O). Mp 3008.
Perchlorate:
Needles (MeOH). Mp 1988.
Marion, L. et al., J.A.C.S., 1948, 70, 691-692;
3253-3254 (isol)
Oung-Boran, et al., Planta Med., 1969, 17, 301-318 (isol)
A-575
Baptisia Alkaloid P
4Struct. unknown. Isol. from Baptisia minor. Oil. Bp0.05175-2008.
Perchlorate:
Needles. Mp 2868.
Marion, L. et al., J.A.C.S., 1948, 70, 3472-3474 (isol)
A-576
C-Alkaloid P
C20H23N2O 307.414
Struct. unknown. Quaternary alkaloid from calabash curare (Strychnos spp.) (Loganiaceae). Mp 224-2328 (as picrate).
Blue col. with Ce(SO4)2.
Giesbrecht, E. et al., Helv. Chim. Acta, 1954, 37, 1974-1982 (isol, uv)
A-577
Lupinus Alkaloid P1
C15H22N2O 246.352
Tentative mol. form. Struct. unknown.
Alkaloid from Lupinus macounii (Fa-baceae). Small plates (EtOH/petrol).
Mp 1268 (sinters at 1238). Salts could not be obt. crystalline. Cooccurs with Anagyrine, A-970 and Lupanine, L-302.
Marion, L. et al., J.A.C.S., 1946, 68, 759-760
A-578
Lupinus Alkaloid P2
C11H18N2O 194.276
Tentative mol. formula. Lupine alkaloid.
Struct. unknown. Alkaloid from Baptisia australis and Baptisia perfoliata (Faba-ceae). Cryst. (MeOH/Et2O). Mp 3008.
Perchlorate:
Needles (MeOH). Mp 1988.
Picrate(?): Mp 2418 (sinters at 1858).
Marion, L. et al., J.A.C.S., 1948, 70, 691-692;
3253-3254 (isol)
A-579
Mucuna pruriens Alkaloid P
Mucuna pruriens Base P C17H26NO6 340.395
Struct. unknown. Alkaloid from Mucuna pruriens (Fabaceae). Bp 118-1198.
Picrate: Mp 100-1018.
Rakhit, S. et al., Indian J. Pharm., 1956, 18, 285; CA, 52, 5748e (isol)
A-580
Alkaloid PAR 1
Struct. unknown. Mol. formula not recorded. Minor alkaloid from Papaver argemone (Papaveraceae). Prisms (MeOH). Mp 193-1958.
Ta´borska´, E. et al., Coll. Czech. Chem. Comm., 1988, 53, 1845 (isol, uv)
A-581
Alkaloid PAR 2
Struct. unknown. Mol. formula not
Alkaloid LV3$ Alkaloid PAR 2 A-564 A-581
recorded. Minor alkaloid from Papaver argemone (Papaveraceae). Prisms (MeOH). Mp 252-2568.
Ta´borska´, E. et al., Coll. Czech. Chem. Comm., 1988, 53, 1845 (isol, uv)
A-582
Alkaloid PAR 3
Struct. unknown. Quaternary alkaloid.
Mol. formula and counterion not speci-fied. Minor alkaloid from Papaver arge-mone (Papaveraceae). Amorph.
Ta´borska´, E. et al., Coll. Czech. Chem. Comm., 1988, 53, 1845 (isol, uv)
A-583
Alkaloid PO3
1-Hydroxy-2,11-dimethoxy-6-methyl-7H-dibenzo[de,g]quinolinium hydroxide inner salt, 9CI
Alkaloid from Papaver orientale (Papa-veraceae). Amorph.
Perchlorate: Mp 253-2558.
Preininger, V. et al., CA, 1967, 67, 54290w (isol)
Preininger, V. et al., Arch. Pharm. (Weinheim, Ger.), 1969, 302, 808 (uv, ir, pmr) Saa´, C. et al., Tet. Lett., 1985, 26, 4559
(synth)
Atanes, N. et al., J.O.C., 1991, 56, 2984 (synth)
Alkaloid from Papaver orientale, Papaver oreophilum, Papaver nudicaule var. leio-carpum, Papaver pyrenaicum ssp. rhoea-ticum and Papaver alboroseum (Papaveraceae).
Preininger, V. et al., Coll. Czech. Chem.
Comm., 1970, 35, 124 (uv, pmr, struct, bibl)
A-585
Alkaloid PP1$
C19H15NO5 337.331
Struct. unknown. Quaternary phenolic protoberberine. Minor alkaloid from
Papaver pavoninum (Papaveraceae). Or-ange needles (MeOH) (as iodide). Mp 2508 dec. (iodide). lmax222 ; 239 ; 251 ; 272 ; 352 (sh) ; 360 ; 468 (MeOH).
Ta´borska´, E. et al., Coll. Czech. Chem. Comm., 1988, 53, 1845 (isol, uv, ir, ms)
A-586
Alkaloid PP1$, 9CI
[158827-53-3]
C17H19NO3 285.342
Struct. unknown, prob. a normorphi-nane. Alkaloid from Papaver pinnatifi-dium (Papaveraceae). Mp 1798.
Laevorotatory.
Slavi´k, J. et al., Coll. Czech. Chem. Comm., 1994, 59, 1879-1883 (isol)
A-587
C-Alkaloid Q
C22H27N3O3 381.474
Minimum formula. Struct. unknown.
Alkaloid from calabash curare (Strychnos spp.) (Loganiaceae). Mp 276-2838 dec.
No col. with Ce(SO4)2.
Meyer, H. et al., Helv. Chim. Acta, 1956, 39, 1208-1213 (isol, uv)
A-588
Mucuna pruriens Alkaloid Q
Mucuna pruriens Base Q
Struct. unknown. Alkaloid from Mucuna pruriens (Fabaceae). Bp 220-2218.
Picrate: Mp 152-1548.
Rakhit, S. et al., Indian J. Pharm., 1956, 18, 285; CA, 52, 5748e (isol)
A-589
Veratrum Alkaloid Q
C32H53NO4 515.775
Steroidal alkaloid. Struct. unknown.
Alkaloid from Veratrum californicum (Liliaceae). Mp 209-2108. [a]25D -95 (CHCl3).
Keeler, R.F. et al., Phytochemistry, 1968, 303 (isol)
A-590
C-Alkaloid R
C21H27N2O2
339.456
Minimum formula. Struct. unknown.
Quaternary alkaloid from calabash cur-are (Strychnos spp.) (Loganiaceae). Violet col. with Ce(SO4)2. UV suggests indoline chromophore resembling C-Alkaloid B, A-400, Alkaloid C, A-436 and C-Alkaloid D, A-476.
Chloride: Mp 3128 dec.
Perchlorate: Mp 3178 dec.
Meyer, H. et al., Helv. Chim. Acta, 1956, 39, 1208-1213 (isol, uv)
A-591
Fritillaria imperialis
Alkaloid R
Fritillaria Base RProb. a steroidal alkaloid. Struct. un-known. Alkaloid from Fritillaria imper-ialis var. lutea (Liliaceae). Mp 134-1368 Mp 213-2158 (double Mp). Co-occurs with Imperonine, I-53.
Hydroiodide: Mp 205-2078.
Perchlorate: Mp 193-1968.
Methiodide: Mp 2698 dec.
Paul, L. et al., Chem. Ber., 1958, 91, 1968
A-592
Lycopodium fawcwttii
Alkaloid R
Lycopodium Base R [53938-16-2]Alkaloid from Lycopodium fawcettii (Ly-copodiaceae). Mp 129-1308. [a]D+104.
Perchlorate: Mp 198-1998.
Burnell, R.H. et al., Can. J. Chem., 1963, 41, 3091 (isol, ir)
Burnell, R.H. et al., Chem. Comm., 1974, 391 (cryst struct)
A-593
Mucuna pruriens Alkaloid R
Mucuna pruriens Base R C23H35NO4 389.534
Struct. unknown. Alkaloid from Mucuna pruriens (Fabaceae). Bp 3208.
Oxalate: Mp 130-1318 dec.
Picrate: Mp 172-1738.
Methiodide: Mp 95-968.
Rakhit, S. et al., Indian J. Pharm., 1956, 18, 285; CA, 52, 5748e (isol)
A-594
Alkaloid RMB 10
[71635-30-8]
N N H H
HOH C
2CH OH
2 C20H26N2O2 326.438Alkaloid from the stem bark of Rauwol-fia mombasiana (Apocynaceae). Yellow amorph. powder.
Iwu, M.M. et al., Planta Med., 1979, 36, 208 (isol, uv, ir, ms, struct)
A-595
Voacanga schweinfurthii
Alkaloid S
2Struct. unknown. Bisindole alkaloid (Aspidosperma-Aspidosperma type).
Alkaloid from the leaves of Voacanga schweinfurthii (Apocynaceae). Mol. for-mula not reported.
Newcombe, F. et al., Planta Med., 1969, 17, 276-280 (isol, uv)
Cordell, G.A. et al., Alkaloids (Academic Press), 1981, 20, 1; 266 (rev)
A-596
Voacanga schweinfurthii
Alkaloid S
3Struct. unknown. Bisindole alkaloid (Aspidosperma-Aspidosperma type).
Alkaloid from the leaves of Voacanga schweinfurthii (Apocynaceae). Mol. for-mula not reported.