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Acknowledgements

We wish to thank Brian Normanly for his English language editing.

References

American Psychiatric Association, 2013. Diagnostic and Statistical Manual of Mental

Disorders, fifth ed. Washington DC.

Abizaid, A., Mineur, Y.S., Roth, R.H., Elsworth, J.D., Sleeman, M.W., Picciotto, M.R., Horvath, T.L., 2011. Reduced locomotor responses to cocaine in ghrelin-deficient mice. Neuroscience 192, 500e506. http://dx.doi.org/10.1016/

j.neuroscience.2011.06.001.

Arteaga, I., Chen, C.C., Reynolds, A.J., 2010. Childhood predictors of adult substance abuse. Child. Youth Serv. Rev. 32 (8), 1108e1120.http://dx.doi.org/10.1016/

j.childyouth.2010.04.025.

Avena, N.M., Rada, P., Hoebel, B.G., 2008. Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake. Neurosci. Biobehav. Rev. 32, 20e39.http://dx.doi.org/10.1016/j.neubiorev.2007.04.019. Bake, T., Morgan, D.G.A., Mercer, J.G., 2014. Feeding and metabolic consequences of

scheduled consumption of large, binge-type meals of high fat diet in the SpragueeDawley rat. Physiol. Behav. 128, 70e79.http://dx.doi.org/10.1016/

j.physbeh.2014.01.018.

Baladi, M.G., Daws, L.C., France, C.P., 2012. You are what you eat: influence of type and amount of food consumed on central dopamine systems and the behavioral effects of direct-and indirect-acting dopamine receptor agonists. Neurophar- macology 63 (1), 76e86.http://dx.doi.org/10.1016/j.neuropharm.2012.02.005. Baladi, M.G., Horton, R.E., Owens, W.A., Daws, L.C., France, C.P., 2015. Eating high fat

chow decreases dopamine clearance in adolescent and adult male rats but selectively enhances the locomotor stimulating effects of cocaine in adoles- cents. Int. J. Neuropsychopharmacol. 18 (7), pyv024.http://dx.doi.org/10.1093/

ijnp/pyv024.

Beck, B., Musse, N., Stricker-Krongrad, A., 2002. Ghrelin, macronutrient intake and dietary preferences in LongeEvans rats. Biochem. Biophys. Res. Commun. 292 (4), 1031e1035.http://dx.doi.org/10.1006/bbrc.2002.6737.

Bello, N.T., Hajnal, A., 2010. Dopamine and binge eating behaviors. Pharmacol. Biochem. Behav. 97 (1), 25e33.http://dx.doi.org/10.1016/j.pbb.2010.04.016. Bello, N.T., Guarda, A.S., Terrillion, C.E., Redgrave, G.W., Coughlin, J.W., Moran, T.H.,

2009. Repeated binge access to a palatable food alters feeding behavior, hor- mone profile, and hindbrain c-Fos responses to a test meal in adult male rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 297 (3), 622e631.http://dx.doi.org/

10.1152/ajpregu.00087.2009.

Bencherif, B., Guarda, A.S., Colantuoni, C., Ravert, H.T., Dannals, R.F., Frost, J.J., 2005.

Regionalm-opioid receptor binding in insular cortex is decreased in bulimia

nervosa and correlates inversely with fasting behavior. J. Nucl. Med. 46 (8),

1349e1351.

Blendy, J.A., Strasser, A., Walters, C.L., Perkins, K.A., Patterson, F., Berkowitz, R., Lerman, C., 2005. Reduced nicotine reward in obesity: cross-comparison in human and mouse. Psychopharmacology 180 (2), 306e315.http://dx.doi.org/

10.1007/s00213-005-2167-9.

Bocarsly, M.E., Berner, L.A., Hoebel, B.G., Avena, N.M., 2011. Rats that binge eat fat- rich food do not show somatic signs or anxiety associated with opiate-like withdrawal: implications for nutrient-specific food addiction behaviors. Phys- iol. Behav. 104 (5), 865e872.http://dx.doi.org/10.1016/j.physbeh.2011.05.018. Brownley, K.A., Berkman, N.D., Sedway, J.A., Lohr, K.N., Bulik, C.M., 2007. Binge

eating disorder treatment: a systematic review of randomized controlled trials. Int. J. Eat. Disord. 40 (4), 337e348.http://dx.doi.org/10.1002/eat.20370. Chefer, V.I., Denoroy, L., Zapata, A., Shippenberg, T.S., 2009. Mu opioid receptor

modulation of somatodendritic dopamine overflow: GABAergic and gluta- matergic mechanisms. Eur. J. Neurosci. 30 (2), 272e278.http://dx.doi.org/

10.1111/j.1460-9568.2009.06827.x.

Collins, G.T., Chen, Y., Tschumi, C., Rush, E.L., Mensah, A., Koek, W., France, C.P., 2015. Effects of consuming a diet high in fat and/or sugar on the locomotor effects of acute and repeated cocaine in male and female C57BL/6J mice. Exp. Clin. Psy- chopharmacol. 23 (4), 228.http://dx.doi.org/10.1037/pha0000019. Corwin, R.L., 2004. Binge-type eating induced by limited access in rats does not

require energy restriction on the previous day. Appetite 42 (2), 139e142.http://

dx.doi.org/10.1016/j.appet.2003.08.010.

Corwin, R.L., Avena, N.M., Boggiano, M.M., 2011. Feeding and reward: perspectives from three rat models of binge eating. Physiol. Behav. 104 (1), 87e97.http://

dx.doi.org/10.1016/j.physbeh.2011.04.041.

Corwin, R.L., Babbs, R.K., 2012. Rodent models of binge eating: are they models of addiction? ILAR J. 53 (1), 23e34.http://dx.doi.org/10.1093/ilar.53.1.23. Corwin, R.L., Buda-Levin, A., 2004. Behavioral models of binge-type eating. Physiol.

Behav. 82 (1), 123e130.http://dx.doi.org/10.1016/j.physbeh.2004.04.036. Corwin, R.L., Wojnicki, F.H.E., Fisher, J.O., Dimitriou, S.G., Rice, H.B., Young, M.A.,

1998. Limited access to a dietary fat option affects ingestive behavior but not body composition in male rats. Physiol. Behav. 65, 545e553.http://dx.doi.org/

10.1016/S0031-9384(98)00201-7.

Cota, D., Tsch€op, M.H., Horvath, T.L., Levine, A.S., 2006. Cannabinoids, opioids and eating behavior: the molecular face of hedonism? Brain Res. Rev. 51 (1), 85e107.

http://dx.doi.org/10.1016/j.brainresrev.2005.10.004.

Cottone, P., Sabino, V., Roberto, M., Bajo, M., Pockros, L., Frihauf, J.B., Conti, B., 2009.

CRF system recruitment mediates dark side of compulsive eating. Proc. Natl. Acad. Sci. 106 (47), 20016e20020.http://dx.doi.org/10.1073/pnas.0908789106. Crews, F.T., Braun, C.J., Hoplight, B., Switzer, R.C., Knapp, D.J., 2000. Binge ethanol consumption causes differential brain damage in young adolescent rats compared with adult rats. Alcohol. Clin. Exp. Res. 24 (11), 1712e1723.http://

dx.doi.org/10.1111/j.1530-0277.2000.tb01973.x.

Cristino, L., Becker, T., Marzo, V., 2014. Endocannabinoids and energy homeostasis: an update. Biofactors 40 (4), 389e397.http://dx.doi.org/10.1002/biof.1168. Davis, C., Carter, J.C., 2009. Compulsive overeating as an addiction disorder. A re-

view of theory and evidence. Appetite 53 (1), 1e8.http://dx.doi.org/10.1016/

j.appet.2009.05.018.

Davis, C., Patte, K., Levitan, R., Reid, C., Tweed, S., Curtis, C., 2007. From motivation to behaviour: a model of reward sensitivity, overeating, and food preferences in the risk profile for obesity. Appetite 48 (1), 12e19.http://dx.doi.org/10.1016/

j.appet.2006.05.016.

Daws, L.C., Avison, M.J., Robertson, S.D., Niswender, K.D., Galli, A., Saunders, C., 2011. Insulin signaling and addiction. Neuropharmacology 61 (7), 1123e1128.http://

dx.doi.org/10.1016/j.neuropharm.2011.02.028.

de Macedo, I.C., de Freitas, J.S., da Silva Torres, I.L., 2016. The influence of palatable diets in reward system activation: a mini review. Adv. Pharmacol. Sci. 2016

http://dx.doi.org/10.1155/2016/7238679.

de Weijer, B.A., van de Giessen, E., van Amelsvoort, T.A., Boot, E., Braak, B., Janssen, I.M., Booij, J., 2011. Lower striatal dopamine D 2/3 receptor availability in obese compared with non-obese subjects. EJNMMI Res. 1 (1), 1.http://

dx.doi.org/10.1186/2191-219X-1-37.

Deshmukh, R., Sharma, P.L., 2012. Activation of central cannabinoid CB1 receptors by WIN 55, 212-2 induces hyperphagia and facilitates preferential increase in palatable diet consumption in Wistar rats. Int. J. Recent Adv. Pharm. Res. 2,

62e69.

Drewnowski, A., Krahn, D.D., Demitrack, M.A., Nairn, K., Gosnell, B.A., 1995. Naloxone, an opiate blocker, reduces the consumption of sweet high-fat foods

in obese and lean female binge eaters. Am. J. Clin. Nutr. 61 (6), 1206e1212.

Esch, T., Stefano, G.B., 2004. The neurobiology of pleasure, reward processes,

addiction and their health implications. Neuroendocrinol. Lett. 25 (4), 235e251.

Figlewicz, D.P., Benoit, S.C., 2009. Insulin, leptin, and food reward: update 2008. Am. J. Physiol. Regul. Integr. Comp. Physiol. 296 (1), R9eR19.http://dx.doi.org/

10.1152/ajpregu.90725.2008.

Figlewicz, D.P., Sipols, A.J., 2010. Energy regulatory signals and food reward. Phar- macol. Biochem. Behav. 97 (1), 15e24. http://dx.doi.org/10.1016/

j.pbb.2010.03.002.

Fulton, S., Pissios, P., Manchon, R.P., Stiles, L., Frank, L., Pothos, E., Maratos-Flier, E., Flier, J.S., 2006. Leptin regulation of the mesoaccumbens dopamine pathway. Neuron 51, 811e822.http://dx.doi.org/10.1016/j.neuron.2006.09.006. Goeders, J.E., Murnane, K.S., Banks, M.L., Fantegrossi, W.E., 2009. Escalation of food-

maintained responding and sensitivity to the locomotor stimulant effects of cocaine in mice. Pharmacol. Biochem. Behav. 93 (1), 67e74.http://dx.doi.org/

10.1016/j.pbb.2009.04.008.

Guertin, T.L., Conger, A.J., 1999. Mood and forbidden foods' influence on perceptions of binge eating. Addict. Behav. 24 (2), 175e193.http://dx.doi.org/10.1016/S0306-

4603(98)00049-5.

Hadigan, C.M., Kissileff, H.R., Walsh, B.T., 1989. Patterns of food selection during

meals in women with bulimia. Am. J. Clin. Nutr. 50 (4), 759e766.

Hajnal, A., Norgren, R., 2002. Repeated access to sucrose augments dopamine turnover in the nucleus accumbens. Neuroreport 13 (17), 2213e2216.http://

dx.doi.org/10.1097/01.wnr.0000044213.09266.38.

Herpertz-Dahlmann, B., 2015. Adolescent eating disorders: update on definitions, symptomatology, epidemiology, and comorbidity. Child Adolesc. Psychiatr. Clin. N. Am. 24 (1), 177e196.http://dx.doi.org/10.1016/j.chc.2008.07.005. Higuchi, S., Irie, K., Yamaguchi, R., Katsuki, M., Araki, M., Ohji, M., Hayakawa, K.,

Mishima, S., Akitake, Y., Matsuyama, K., Mishima, K., Iwasaki, K., Fujiwara, M., 2012. Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences. PLoS One 7, e38609.http://dx.doi.org/10.1371/

journal.pone.0038609.

Higuchi, S., Ohji, M., Araki, M., Furuta, R., Katsuki, M., Yamaguchi, R., Akitake, Y., Matsuyama, K., Irie, K., Mishima, K., 2011. Increment of hypothalamic 2- arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors. Behav. Brain Res. 216 (1), 477e480.http://

dx.doi.org/10.1016/j.bbr.2010.08.042.

Hudson, J.I., Hiripi, E., Pope, H.G., Kessler, R.C., 2007. The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication. Biol. Psy- chiatry 61 (3), 348e358.http://dx.doi.org/10.1016/j.biopsych.2006.03.040. Jean, A., Conductier, G., Manrique, C., Bouras, C., Berta, P., Hen, R., Compan, V., 2007.

Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proc. Natl. Acad. Sci. 104 (41), 16335e16340.http://dx.doi.org/10.1073/pnas.0701471104.

Jean, A., Laurent, L., Bockaert, J., Charnay, Y., Dusticier, N., Nieoullon, A., Compan, V., 2012. The nucleus accumbens 5-HTR4-CART pathway ties anorexia to hyper- activity. Transl. Psychiatry 2 (12), e203.http://dx.doi.org/10.1038/tp.2012.131. Jerlhag, E., Egecioglu, E., Dickson, S.L., Engel, J.A., 2010. Ghrelin receptor antagonism

attenuates cocaine-and amphetamine-induced locomotor stimulation, accum- bal dopamine release, and conditioned place preference. Psychopharmacology 211 (4), 415e422.http://dx.doi.org/10.1007/s00213-010-1907-7. Johnson, P.M., Kenny, P.J., 2010. Dopamine D2 receptors in addiction-like reward

dysfunction and compulsive eating in obese rats. Nat. Neurosci. 13 (5), 635e641.

http://dx.doi.org/10.1038/nn.2519.

M.C. Blanco-Gandía et al. / Neuropharmacology 113 (2017) 31e44 42

Johnson, S.W., North, R.A., 1992. Opioids excite dopamine neurons by hyperpolar-

ization of local interneurons. J. Neurosci. 12 (2), 483e488.

Kales, E.F., 1990. Macronutrient analysis of binge eating in bulimia. Physiol. Behav. 48 (6), 837e840.http://dx.doi.org/10.1016/0031-9384(90)90236-W. Kawahara, Y., Kawahara, H., Kaneko, F., Yamada, M., Nishi, Y., Tanaka, E., Nishi, A.,

2009. Peripherally administered ghrelin induces bimodal effects on the meso- limbic dopamine system depending on food-consumptive states. Neuroscience 161 (3), 855e864.http://dx.doi.org/10.1016/j.neuroscience.2009.03.086. Kawahara, Y., Kaneko, F., Yamada, M., Kishikawa, Y., Kawahara, H., Nishi, A., 2013.

Food reward-sensitive interaction of ghrelin and opioid receptor pathways in mesolimbic dopamine system. Neuropharmacology 67, 395e402.http://

dx.doi.org/10.1016/j.neuropharm.2012.11.022.

Kelley, A.E., Schiltz, C.A., Landry, C.F., 2005. Neural systems recruited by drug-and food-related cues: studies of gene activation in corticolimbic regions. Physiol. Behav. 86 (1), 11e14.http://dx.doi.org/10.1016/j.physbeh.2005.06.018. Kelley, A.E., Will, M.J., Steininger, T.L., Zhang, M., Haber, S.N., 2003. Restricted daily

consumption of a highly palatable food (chocolate Ensure®) alters striatal enkephalin gene expression. Eur. J. Neurosci. 18 (9), 2592e2598.http://

dx.doi.org/10.1046/j.1460-9568.2003.02991.x.

King, S.J., Isaacs, A.M., O’farrell, E., Abizaid, A., 2011. Motivation to obtain preferred foods is enhanced by ghrelin in the ventral tegmental area. Horm. Behav. 60 (5), 572e580.http://dx.doi.org/10.1016/j.yhbeh.2011.08.006.

King, S.J., Rodrigues, T., Watts, A., Murray, E., Wilson, A., Abizaid, A., 2016. Investi- gation of a role for ghrelin signaling in binge-like feeding in mice under limited access to high-fat diet. Neuroscience 319, 233e245.http://dx.doi.org/10.1016/

j.neuroscience.2016.01.004.

Koob, G.F., Zorrilla, E.P., 2010. Neurobiological mechanisms of addiction: focus on corticotropin-releasing factor. Curr. Opin. Investig. Drugs (London, Engl. 2000)

11 (1), 63.

Kurose, Y., Iqbal, J., Rao, A., Murata, Y., Hasegawa, Y., Terashima, Y., Clarke, I.J., 2005. Changes in expression of the genes for the leptin receptor and the growth hormone-releasing peptide/ghrelin receptor in the hypothalamic arcuate nu- cleus with long-term manipulation of adiposity by dietary means. J. Neuroendocrinol. 17 (6), 331e340. http://dx.doi.org/10.1111/j.1365-

2826.2005.01318.x.

Li, Y., South, T., Han, M., Chen, J., Wang, R., Huang, X.F., 2009. High-fat diet decreases tyrosine hydroxylase mRNA expression irrespective of obesity susceptibility in mice. Brain Res. 1268, 181e189. http://dx.doi.org/10.1016/

j.brainres.2009.02.075.

Liang, N.C., Hajnal, A., Norgren, R., 2006. Sham feeding corn oil increases accumbens dopamine in the rat. American Journal of Physiology-Regulatory. Integr. Comp. Physiol. 291 (5), R1236eR1239.http://dx.doi.org/10.1152/ajpregu.00226.2006. Lindqvist, A., de la Cour, C.D., Stegmark, A., Håkanson, R., Erlanson-Albertsson, C., 2005. Overeating of palatable food is associated with blunted leptin and ghrelin responses. Regul. Pept. 130 (3), 123e132. http://dx.doi.org/10.1016/

j.regpep.2005.05.002.

Lindqvist, A., Baelemans, A., Erlanson-Albertsson, C., 2008. Effects of sucrose, glucose and fructose on peripheral and central appetite signals. Regul. Pept. 150 (1), 26e32.http://dx.doi.org/10.1016/j.regpep.2008.06.008.

Livak, K.J., Schmittgen, T.D., 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25

(4), 402e408.

Maldonado, C., Rodríguez-Arias, M., Castillo, A., Aguilar, M.A., Mi~narro, J., 2006. Gamma-hydroxybutyric acid affects the acquisition and reinstatement of cocaine-induced conditioned place preference in mice. Behav. Pharmacol. 17, 119e131.http://dx.doi.org/10.1097/01.fbp.0000190685.84984.ec. Martire, S.I., Maniam, J., South, T., Holmes, N., Westbrook, R.F., Morris, M.J., 2014.

Extended exposure to a palatable cafeteria diet alters gene expression in brain regions implicated in reward, and withdrawal from this diet alters gene expression in brain regions associated with stress. Behav. Brain Res. 265, 132e141.http://dx.doi.org/10.1016/j.bbr.2014.02.027.

Massa, F., Mancini, G., Schmidt, H., Steindel, F., Mackie, K., Angioni, C., Oliet, S.H., Geisslinger, G., Lutz, B., 2010. Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. J. Neurosci. 30, 6273e6281.http://

dx.doi.org/10.1523/JNEUROSCI.2648-09.2010.

Mellis, T., Succu, S., Sanna, F., Boi, A., Argiolas, A., Melis, M.R., 2007. The cannabinoid antagonist SR 141716A (Rimonabant) reduces the increase of extra-cellular dopamine release in the rat nucleus accumbens induced by a novel high palatable food. Neurosci. Lett. 419, 231e235. http://dx.doi.org/10.1016/

j.neulet.2007.04.012.

Merline, A.C., O'malley, P.M., Schulenberg, J.E., Bachman, J.G., Johnston, L.D., 2004. Substance use among adults 35 years of age: prevalence, adulthood predictors, and impact of adolescent substance use. Am. J. Public Health 94 (1), 96e102.

http://dx.doi.org/10.2105/AJPH.94.1.96.

Morales, L., Del Olmo, N., Valladolid-Acebes, I., Fole, A., Cano, V., Merino, B., Stucchi, P., Ruggieri, D., L�opez, L., Alguacil, L.F., Ruiz-Gayo, M., 2012. Shift of circadian feeding pattern by high-fat diets is coincident with reward deficits in obese mice. PloS One 7 (5).http://dx.doi.org/10.1371/journal.pone.0036139. Murray, S., Tulloch, A., Gold, M.S., Avena, N.M., 2014. Hormonal and neural mech-

anisms of food reward, eating behaviour and obesity. Nat. Rev. Endocrinol. 10 (9), 540e552.http://dx.doi.org/10.1038/nrendo.2014.91.

Naef, L., Pitman, K.A., Borgland, S.L., 2015. Mesolimbic dopamine and its neuro- modulators in obesity and binge eating. CNS Spectr. 20 (06), 574e583.http://

dx.doi.org/10.1017/S1092852915000693.

Naleid, A.M., Grace, M.K., Cummings, D.E., Levine, A.S., 2005. Ghrelin induces

feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens. Peptides 26 (11), 2274e2279.http://dx.doi.org/

10.1016/j.peptides.2005.04.025.

Narayanaswami, V., Thompson, A.C., Cassis, L.A., Bardo, M.T., Dwoskin, L.P., 2013. Diet-induced obesity: dopamine transporter function, impulsivity and moti- vation. Int. J. Obes. 37 (8), 1095e1103.http://dx.doi.org/10.1038/ijo.2012.178. Ong, Z.Y., Wanasuria, A.F., Lin, M.Z., Hiscock, J., Muhlhausler, B.S., 2013. Chronic

intake of a cafeteria diet and subsequent abstinence. Sex-specific effects on gene expression in the mesolimbic reward system. Appetite 65, 189e199.

http://dx.doi.org/10.1016/j.appet.2013.01.014.

Palkovits, M., 1983. Punch sampling biopsy technique. Methods Enzymol. 103, 368e376.http://dx.doi.org/10.1016/S0076-6879(83)03025-6.

Parylak, S.L., Cottone, P., Sabino, V., Rice, K.C., Zorrilla, E.P., 2012. Effects of CB1 and CRF1 receptor antagonists on binge-like eating in rats with limited access to a sweet fat diet: lack of withdrawal-like responses. Physiol. Behav. 107 (2), 231e242.http://dx.doi.org/10.1016/j.physbeh.2012.06.017.

Pascual, M., Boix, J., Felipo, V., Guerri, C., 2009. Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glu- tamatergic systems and promotes alcohol intake in the adult rat. J. Neurochem. 108 (4), 920e931.http://dx.doi.org/10.1111/j.1471-4159.2008.05835.x. Pascual, M., Do Couto, B.R., Alfonso-Loeches, S., Aguilar, M.A., Rodriguez-Arias, M.,

Guerri, C., 2012. Changes in histone acetylation in the prefrontal cortex of ethanol-exposed adolescent rats are associated with ethanol-induced place conditioning. Neuropharmacology 62 (7), 2309e2319. http://dx.doi.org/

10.1016/j.neuropharm.2012.01.011.

Paxinos, G., Franklin, K.B.J., 2001. The Mouse Brain in Stereotaxic Coordinates. Ac-

ademic Press. Harcourt Science and Technology Company, New York.

Pellow, S., File, S.E., 1986. Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat. Pharmacol. Biochem. Behav. 24 (3), 525e529.http://dx.doi.org/10.1016/0091-3057(86)

90552-6.

Puhl, M.D., Cason, A.M., Wojnicki, F.H., Corwin, R.L., Grigson, P.S., 2011. A history of bingeing on fat enhances cocaine seeking and taking. Behav. Neurosci. 125 (6),

930.http://dx.doi.org/10.1037/a0025759.

Rada, P., Avena, N.M., Hoebel, B.G., 2005. Daily bingeing on sugar repeatedly re- leases dopamine in the accumbens shell. Neuroscience 134 (3), 737e744.http://

dx.doi.org/10.1016/j.neuroscience.2005.04.043.

Ravinet-Trillou, C., Delgorge, C., Menet, C., Arnone, M., Soubrie, P., 2004. CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet- induced obesity and enhanced leptin sensitivity. Int. J. Obes. 28 (4), 640e648.

http://dx.doi.org/10.1038/sj.ijo.0802583.

Rkieh, N., Cloke, J.M., Gallagher, N., Winters, B.D., Leri, F., 2014. Drugs of abuse as memory modulators: a study of cocaine in rats. Psychopharmacology 231 (11), 2339e2348.http://dx.doi.org/10.1007/s00213-013-3390-4.

Robinson, T.E., Berridge, K.C., 2008. Review. The incentive sensitization theory of addiction: some current issues. Philos. Trans. R. Soc. Lond. Ser. B, Biol. Sci. 363 (1507), 3137e3146.http://dx.doi.org/10.1098/rstb.2008.0093.

Rodgers, R.J., Cao, B.J., Dalvi, A., Holmes, A., 1997. Animal models of anxiety: an ethological perspective. Braz. J. Med. Biol. Res. 30, 289e304.http://dx.doi.org/

10.1590/S0100-879X1997000300002.

Rodríguez-Arias, M., Montagud-Romero, S., Rubio-Araiz, A., Aguilar, M.A., Martín- García, E., Cabrera, R., Maldonado, R., Porcu, F., Colado, M.I., Mi~narro, J., 2016. Effects of repeated social defeat on adolescent mice on cocaine-induced CPP and self-administration in adulthood: integrity of the blood-brain barrier. Addict. Biol.http://dx.doi.org/10.1111/adb.12301.

Schellekens, H., Finger, B.C., Dinan, T.G., Cryan, J.F., 2012. Ghrelin signalling and obesity: at the interface of stress, mood and food reward. Pharmacol. Ther. 135 (3), 316e326.http://dx.doi.org/10.1016/j.pharmthera.2012.06.004. Serafine, K.M., Bentley, T.A., Koek, W., France, C.P., 2015. Eating high fat chow, but

not drinking sucrose or saccharin, enhances the development of sensitization to the locomotor effects of cocaine in adolescent female rats. Behav. Pharmacol. 26 (3), 321e325.http://dx.doi.org/10.1097/FBP.0000000000000114. Sharma, S., Fernandes, M.F., Fulton, S., 2013. Adaptations in brain reward circuitry

underlie palatable food cravings and anxiety induced by high-fat diet with- drawal. Int. J. Obes. 37 (9), 1183e1191.http://dx.doi.org/10.1038/ijo.2012.197. Sharma, S., Fulton, S., 2013. Diet-induced obesity promotes depressive-like behav-

iour that is associated with neural adaptations in brain reward circuitry. Int. J. Obes. 37 (3), 382e389.http://dx.doi.org/10.1038/ijo.2012.48.

Skibicka, K.P., Shirazi, R.H., Hansson, C., Dickson, S.L., 2011. Ghrelin interacts with neuropeptide Y Y1 and opioid receptors to increase food reward. Endocrinology 153 (3), 1194e1205. http://dx.doi.org/10.1210/en.2011-

1606#sthash.s97lXNTS.dpuf.

Skibicka, K.P., Hansson, C., Egecioglu, E., Dickson, S.L., 2012. Role of ghrelin in food reward: impact of ghrelin on sucrose self-administration and mesolimbic dopamine and acetylcholine receptor gene expression. Addict. Biol. 17 (1), 95e107.http://dx.doi.org/10.1111/j.1369-1600.2010.00294.x.

Smith, S.L., Harrold, J.A., Williams, G., 2002. Diet-induced obesity increasesmopioid receptor binding in specific regions of the rat brain. Brain Res. 953 (1), 215e222.

http://dx.doi.org/10.1016/S0006-8993(02)03291-2.

Soria, G., Mendizabal, V., Tourino, C., Robledo, P., Ledent, C., Parmentier, M., Maldonado, R., Valverde, O., 2005. Lack of CB1 cannabinoid receptor impairs cocaine self-administration. Neuropsychopharmacology 30, 1670e1680.http://

dx.doi.org/10.1038/sj.npp.1300707.

South, T., Huang, X.F., 2008. High-fat diet exposure increases dopamine D2 receptor and decreases dopamine transporter receptor binding density in the nucleus M.C. Blanco-Gandía et al. / Neuropharmacology 113 (2017) 31e44 43

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