70. Agranoff, D., and S. Krishna. 2004. Metal ion transport and regulation in Mycobacterium tuberculosis.
Frontiers in bioscience : a journal and virtual library 9:2996-3006.
71. Papp-Wallace, K. M., and M. E. Maguire. 2006. Manganese transport and the role of manganese in
virulence. Annual review of microbiology 60:187-209.
72. Armstrong, S. K., and R. Gross. 2007. Primary Metabolism and Physiology of Bordetella Species, p.
165-190. In C. Locht (ed.), Bordetella Molecular Microbiology, vol. First. Horizon Bioscience, Norfolk UK. 73. Renauld-Mongenie, G., J. Cornette, N. Mielcarek, F. D. Menozzi, and C. Locht. 1996. Distinct roles of
the N-terminal and C-terminal precursor domains in the biogenesis of the Bordetella pertussis filamentous hemagglutinin. Journal of bacteriology 178:1053-1060.
74. Coutte, L., R. Antoine, H. Drobecq, C. Locht, and F. Jacob-Dubuisson. 2001. Subtilisin-like
autotransporter serves as maturation protease in a bacterial secretion pathway. The EMBO journal
20:5040-5048.
75. Siezen, R. J., and J. A. Leunissen. 1997. Subtilases: the superfamily of subtilisin-like serine proteases.
Protein science : a publication of the Protein Society 6:501-523.
76. Mazar, J., and P. A. Cotter. 2006. Topology and maturation of filamentous haemagglutinin suggest a new
model for two-partner secretion. Molecular microbiology 62:641-654.
77. Coutte, L., S. Alonso, N. Reveneau, E. Willery, B. Quatannens, C. Locht, and F. Jacob-Dubuisson.
2003. Role of adhesin release for mucosal colonization by a bacterial pathogen. The Journal of experimental medicine 197:735-742.
78. Blom, J., G. A. Hansen, and F. M. Poulsen. 1983. Morphology of cells and hemagglutinogens of Bordetella
species: resolution of substructural units in fimbriae of Bordetella pertussis. Infection and immunity 42:308-
317.
79. Geuijen, C. A., R. J. Willems, M. Bongaerts, J. Top, H. Gielen, and F. R. Mooi. 1997. Role of the
Bordetella pertussis minor fimbrial subunit, FimD, in colonization of the mouse respiratory tract. Infection and immunity 65:4222-4228.
80. Locht, C., M. C. Geoffroy, and G. Renauld. 1992. Common accessory genes for the Bordetella pertussis
filamentous hemagglutinin and fimbriae share sequence similarities with the papC and papD gene families. The EMBO journal 11:3175-3183.
81. Willems, R. J., C. Geuijen, H. G. van der Heide, M. Matheson, A. Robinson, L. F. Versluis, R. Ebberink, J. Theelen, and F. R. Mooi. 1993. Isolation of a putative fimbrial adhesin from Bordetella pertussis and the
identification of its gene. Molecular microbiology 9:623-634.
82. Willems, R. J., H. G. van der Heide, and F. R. Mooi. 1992. Characterization of a Bordetella pertussis
fimbrial gene cluster which is located directly downstream of the filamentous haemagglutinin gene. Molecular microbiology 6:2661-2671.
83. Willems, R. J., C. Geuijen, H. G. van der Heide, G. Renauld, P. Bertin, W. M. van den Akker, C. Locht, and F. R. Mooi. 1994. Mutational analysis of the Bordetella pertussis fim/fha gene cluster: identification
of a gene with sequence similarities to haemolysin accessory genes involved in export of FHA. Molecular microbiology 11:337-347.
84. Geuijen, C. A., R. J. Willems, P. Hoogerhout, W. C. Puijk, R. H. Meloen, and F. R. Mooi. 1998.
Identification and characterization of heparin binding regions of the Fim2 subunit of Bordetella pertussis. Infection and immunity 66:2256-2263.
85. Henderson, I. R., and J. P. Nataro. 2001. Virulence functions of autotransporter proteins. Infection and
immunity 69:1231-1243.
86. Leininger, E., M. Roberts, J. G. Kenimer, I. G. Charles, N. Fairweather, P. Novotny, and M. J. Brennan.
1991. Pertactin, an Arg-Gly-Asp-containing Bordetella pertussis surface protein that promotes adherence of mammalian cells. Proceedings of the National Academy of Sciences of the United States of America
88:345-349.
87. Charles, I. G., G. Dougan, D. Pickard, S. Charfield, M. Smith, P. Novotny, and N. Fairweather. 1988.
Molecular cloning and analysis of P. 69, a vir-controlled protein from Bordetella pertussis. The Tokai journal of experimental and clinical medicine 13 Suppl:227-234.
88. Makoff, A. J., M. D. Oxer, S. P. Ballantine, N. F. Fairweather, and I. G. Charles. 1990. Protective surface
antigen P69 of Bordetella pertussis: its characterization and very high level expression in Escherichia coli. Bio/technology 8:1030-1033.
89. Emsley, P., I. G. Charles, N. F. Fairweather, and N. W. Isaacs. 1996. Structure of Bordetella pertussis
virulence factor P.69 pertactin. Nature 381:90-92.
90. Carbonetti, N. H. 2010. Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella
pertussis and cell biology tools. Future microbiology 5:455-469.
91. Locht, C., L. Coutte, and N. Mielcarek. 2011. The ins and outs of pertussis toxin. The FEBS journal 278:4668-4682.
92. Verma, A., and D. L. Burns. 2007. Requirements for assembly of PtlH with the pertussis toxin transporter
apparatus of Bordetella pertussis. Infection and immunity 75:2297-2306.
by the C terminus of PtlD. Journal of bacteriology 190:7285-7290.
94. Heerze, L. D., P. C. Chong, and G. D. Armstrong. 1992. Investigation of the lectin-like binding domains
in pertussis toxin using synthetic peptide sequences. Identification of a sialic acid binding site in the S2 subunit of the toxin. The Journal of biological chemistry 267:25810-25815.
95. Saukkonen, K., W. N. Burnette, V. L. Mar, H. R. Masure, and E. I. Tuomanen. 1992. Pertussis toxin has
eukaryotic-like carbohydrate recognition domains. Proceedings of the National Academy of Sciences of the United States of America 89:118-122.
96. Vojtova, J., J. Kamanova, and P. Sebo. 2006. Bordetella adenylate cyclase toxin: a swift saboteur of host
defense. Current opinion in microbiology 9:69-75.
97. Hackett, M., C. B. Walker, L. Guo, M. C. Gray, S. Van Cuyk, A. Ullmann, J. Shabanowitz, D. F. Hunt, E. L. Hewlett, and P. Sebo. 1995. Hemolytic, but not cell-invasive activity, of adenylate cyclase toxin is
selectively affected by differential fatty-acylation in Escherichia coli. The Journal of biological chemistry
270:20250-20253.
98. Boyd, A. P., P. J. Ross, H. Conroy, N. Mahon, E. C. Lavelle, and K. H. Mills. 2005. Bordetella pertussis
adenylate cyclase toxin modulates innate and adaptive immune responses: distinct roles for acylation and enzymatic activity in immunomodulation and cell death. Journal of immunology 175:730-738.
99. Gray, M. C., G. M. Donato, F. R. Jones, T. Kim, and E. L. Hewlett. 2004. Newly secreted adenylate
cyclase toxin is responsible for intoxication of target cells by Bordetella pertussis. Molecular microbiology
53:1709-1719.
100. Zaretzky, F. R., M. C. Gray, and E. L. Hewlett. 2002. Mechanism of association of adenylate cyclase toxin
with the surface of Bordetella pertussis: a role for toxin-filamentous haemagglutinin interaction. Molecular microbiology 45:1589-1598.
101. Cossart, P., and P. J. Sansonetti. 2004. Bacterial invasion: the paradigms of enteroinvasive pathogens.
Science 304:242-248.
102. Hueck, C. J. 1998. Type III protein secretion systems in bacterial pathogens of animals and plants.
Microbiology and molecular biology reviews : MMBR 62:379-433.
103. Yuk, M. H., E. T. Harvill, P. A. Cotter, and J. F. Miller. 2000. Modulation of host immune responses,
induction of apoptosis and inhibition of NF-kappaB activation by the Bordetella type III secretion system. Molecular microbiology 35:991-1004.
104. Yuk, M. H., E. T. Harvill, and J. F. Miller. 1998. The BvgAS virulence control system regulates type III
secretion in Bordetella bronchiseptica. Molecular microbiology 28:945-959.
105. Fennelly, N. K., F. Sisti, S. C. Higgins, P. J. Ross, H. van der Heide, F. R. Mooi, A. Boyd, and K. H. Mills. 2008. Bordetella pertussis expresses a functional type III secretion system that subverts protective
innate and adaptive immune responses. Infection and immunity 76:1257-1266.
106. French, C. T., E. M. Panina, S. H. Yeh, N. Griffith, D. G. Arambula, and J. F. Miller. 2009. The Bordetella
type III secretion system effector BteA contains a conserved N-terminal motif that guides bacterial virulence factors to lipid rafts. Cellular microbiology 11:1735-1749.
107. Kuwae, A., T. Matsuzawa, N. Ishikawa, H. Abe, T. Nonaka, H. Fukuda, S. Imajoh-Ohmi, and A. Abe.
2006. BopC is a novel type III effector secreted by Bordetella bronchiseptica and has a critical role in type III-dependent necrotic cell death. The Journal of biological chemistry 281:6589-6600.
108. Goldman, W. E., D. G. Klapper, and J. B. Baseman. 1982. Detection, isolation, and analysis of a released
Bordetella pertussis product toxic to cultured tracheal cells. Infection and immunity 36:782-794.
109. Goldman, W. E., and L. A. Herwaldt. 1985. Bordetella pertussis tracheal cytotoxin. Developments in
biological standardization 61:103-111.
110. Rosenthal, R. S., W. Nogami, B. T. Cookson, W. E. Goldman, and W. J. Folkening. 1987. Major
fragment of soluble peptidoglycan released from growing Bordetella pertussis is tracheal cytotoxin. Infection and immunity 55:2117-2120.
111. Relman, D. A., M. Domenighini, E. Tuomanen, R. Rappuoli, and S. Falkow. 1989. Filamentous
hemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence. Proceedings of the National Academy of Sciences of the United States of America 86:2637-2641.
112. Rodriguez, M. E., S. M. Hellwig, M. L. Perez Vidakovics, G. A. Berbers, and J. G. van de Winkel.
2006. Bordetella pertussis attachment to respiratory epithelial cells can be impaired by fimbriae-specific antibodies. FEMS immunology and medical microbiology 46:39-47.
113. van den Berg, B. M., H. Beekhuizen, R. J. Willems, F. R. Mooi, and R. van Furth. 1999. Role of Bordetella
pertussis virulence factors in adherence to epithelial cell lines derived from the human respiratory tract. Infection and immunity 67:1056-1062.
114. Tuomanen, E., A. Weiss, R. Rich, F. Zak, and O. Zak. 1985. Filamentous hemagglutinin and pertussis
toxin promote adherence of Bordetella pertussis to cilia. Developments in biological standardization
61:197-204.
115. Tuomanen, E., H. Towbin, G. Rosenfelder, D. Braun, G. Larson, G. C. Hansson, and R. Hill. 1988.
Receptor analogs and monoclonal antibodies that inhibit adherence of Bordetella pertussis to human ciliated respiratory epithelial cells. The Journal of experimental medicine 168:267-277.
1